ID A0A0D6AEN4_9CHRO Unreviewed; 476 AA.
AC A0A0D6AEN4;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=NAD-reducing hydrogenase subunit HoxH {ECO:0000313|EMBL:BAQ61247.1};
GN ORFNames=GM3708_1653 {ECO:0000313|EMBL:BAQ61247.1};
OS Geminocystis sp. NIES-3708.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Oscillatoriophycideae;
OC Chroococcales; Geminocystaceae; Geminocystis.
OX NCBI_TaxID=1615909 {ECO:0000313|EMBL:BAQ61247.1, ECO:0000313|Proteomes:UP000060542};
RN [1] {ECO:0000313|EMBL:BAQ61247.1, ECO:0000313|Proteomes:UP000060542}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-3708 {ECO:0000313|EMBL:BAQ61247.1,
RC ECO:0000313|Proteomes:UP000060542};
RA Hirose Y.;
RT "Geminocystis sp. NIES-3708 complete genome sequence.";
RL Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Fe cation; Xref=ChEBI:CHEBI:24875;
CC Evidence={ECO:0000256|PIRSR:PIRSR601501-1};
CC -!- COFACTOR:
CC Name=Ni(2+); Xref=ChEBI:CHEBI:49786;
CC Evidence={ECO:0000256|PIRSR:PIRSR601501-1};
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DR EMBL; AP014815; BAQ61247.1; -; Genomic_DNA.
DR RefSeq; WP_066345442.1; NZ_AP014815.1.
DR AlphaFoldDB; A0A0D6AEN4; -.
DR STRING; 1615909.GM3708_1653; -.
DR KEGG; gee:GM3708_1653; -.
DR PATRIC; fig|1615909.3.peg.1683; -.
DR OrthoDB; 9761717at2; -.
DR Proteomes; UP000060542; Chromosome.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0008901; F:ferredoxin hydrogenase activity; IEA:InterPro.
DR GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR GO; GO:0048038; F:quinone binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.645.10; Cytochrome-c3 Hydrogenase, chain B; 1.
DR InterPro; IPR001501; Ni-dep_hyd_lsu.
DR InterPro; IPR018194; Ni-dep_hyd_lsu_Ni_BS.
DR InterPro; IPR029014; NiFe-Hase_large.
DR PANTHER; PTHR43600; COENZYME F420 HYDROGENASE, SUBUNIT ALPHA; 1.
DR PANTHER; PTHR43600:SF2; CYTOSOLIC NIFE-HYDROGENASE, ALPHA SUBUNIT; 1.
DR Pfam; PF00374; NiFeSe_Hases; 2.
DR SUPFAM; SSF56762; HydB/Nqo4-like; 1.
DR PROSITE; PS00508; NI_HGENASE_L_2; 1.
PE 4: Predicted;
KW Homeobox {ECO:0000313|EMBL:BAQ61247.1};
KW Iron {ECO:0000256|PIRSR:PIRSR601501-1};
KW Magnesium {ECO:0000256|PIRSR:PIRSR601501-1};
KW Metal-binding {ECO:0000256|PIRSR:PIRSR601501-1};
KW Nickel {ECO:0000256|PIRSR:PIRSR601501-1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Quinone {ECO:0000256|ARBA:ARBA00022719};
KW Reference proteome {ECO:0000313|Proteomes:UP000060542}.
FT BINDING 43
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR601501-1"
FT BINDING 62
FT /ligand="Ni(2+)"
FT /ligand_id="ChEBI:CHEBI:49786"
FT /evidence="ECO:0000256|PIRSR:PIRSR601501-1"
FT BINDING 65
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000256|PIRSR:PIRSR601501-1"
FT BINDING 65
FT /ligand="Ni(2+)"
FT /ligand_id="ChEBI:CHEBI:49786"
FT /evidence="ECO:0000256|PIRSR:PIRSR601501-1"
FT BINDING 399
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR601501-1"
FT BINDING 445
FT /ligand="Ni(2+)"
FT /ligand_id="ChEBI:CHEBI:49786"
FT /evidence="ECO:0000256|PIRSR:PIRSR601501-1"
FT BINDING 448
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /evidence="ECO:0000256|PIRSR:PIRSR601501-1"
FT BINDING 451
FT /ligand="Mg(2+)"
FT /ligand_id="ChEBI:CHEBI:18420"
FT /evidence="ECO:0000256|PIRSR:PIRSR601501-1"
SQ SEQUENCE 476 AA; 53145 MW; 056B315D342EBEC3 CRC64;
MTKTVIIDPV TRIEGHAKIS IYLDDNGEVN DARFHVVEFR GFEKFCEGRP MFEMAGITAR
ICGICPVSHL LASAKTGDKI LGVKIPPTGE KLRRMMNLAQ ITQSHALSFF HLSSPDFLLG
WESNPSTRNV FGLMAADPDL ARAGIRLRAF GQNIIEILGA RKIHAAWAVP GGVRSPLSTE
NRQWIEDNLP EAKQTTELAL NLFKKLLDSE LKTEIDVFGK FESLFMGLVA PDGTWEHYGG
HLRFINSQGN IIADGLSEDN YQDFLGEAVE NWSYLKFPYY KPLGYPDGIY RVGPLARLNL
CDRIGTPQAD RELQEFRHRA GSRVATSSFF YHYARLIEIV ACLEAIENLI HDPDILSTRV
RAEAGINYLE GIGVSEAPRG TLFHHYNVDD NGLIKKVNLI IATGQNNLAM NKTVTQIAKH
YIHGEDIPEA MLNRVEAGIR AFDPCLSCST HAIGQMPLHI ELVDSKGKII TEKYKN
//
