ID A0A0D6DWT2_9LACT Unreviewed; 425 AA.
AC A0A0D6DWT2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE SubName: Full=Uracil permease PyrP {ECO:0000313|EMBL:CEN28219.1};
GN Name=pyrP {ECO:0000313|EMBL:CEN28219.1};
GN ORFNames=LACPI_1019 {ECO:0000313|EMBL:CEN28219.1};
OS Lactococcus piscium MKFS47.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=297352 {ECO:0000313|EMBL:CEN28219.1, ECO:0000313|Proteomes:UP000033166};
RN [1] {ECO:0000313|Proteomes:UP000033166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MKFS47 {ECO:0000313|Proteomes:UP000033166};
RA Andreevskaya M.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; LN774769; CEN28219.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D6DWT2; -.
DR STRING; 1364.LP2241_30003; -.
DR KEGG; lpk:LACPI_1019; -.
DR HOGENOM; CLU_017959_1_2_9; -.
DR Proteomes; UP000033166; Chromosome I.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR InterPro; IPR006042; Xan_ur_permease.
DR NCBIfam; TIGR00801; ncs2; 1.
DR PANTHER; PTHR42810; PURINE PERMEASE C1399.01C-RELATED; 1.
DR PANTHER; PTHR42810:SF2; PURINE PERMEASE C1399.01C-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
DR PROSITE; PS01116; XANTH_URACIL_PERMASE; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 127..145
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 157..176
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 182..200
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 316..340
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..367
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 379..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 401..419
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 425 AA; 45285 MW; 4DE7487B5CA10437 CRC64;
MTKNNDVIYD VHDKPPVGMW FGLSFQHLFA MFGSTVLVPI LVGIDPSIAL FSSGLGTLAH
LTVTKYKIPA YMGSSFAYIL AMQSLMKSDG IAAVAQGAVV GGLVYLIVAL IVKFIGKDWI
DKVLPPIVVG PIVMVIGLSL AGTAVNDAMN RDGVYNLTFL LIALVTLFSV LAFNMFGKGL
TSLIPILLGI VVGYIFTLII QKLTGMTIIS FDEIAKSSWL GLPKFDIMFI DYHFKLYPSA
ILTMAPIAFV TMTEHFGHIM VLNSLTKRDY FKDPGLERTL TGDGIAQIIA GFFGAPPVTS
YGENIGVMAI TKIHSVYVIS GAAIFAVVLS FIGKVSALIH SIPTPVIGGV SIALFGVIAA
SGLKILVENK VNFDDKRNLL IASVILVSGI GGLTLNVAGI SISGIAFSTI LGILMHLILP
KTVEN
//
