ID A0A0D6DY85_9LACT Unreviewed; 332 AA.
AC A0A0D6DY85;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=Catabolite control protein A {ECO:0000256|ARBA:ARBA00019435, ECO:0000256|RuleBase:RU368079};
GN Name=ccpA {ECO:0000313|EMBL:CEN28732.1};
GN ORFNames=LACPI_1532 {ECO:0000313|EMBL:CEN28732.1};
OS Lactococcus piscium MKFS47.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Lactococcus.
OX NCBI_TaxID=297352 {ECO:0000313|EMBL:CEN28732.1, ECO:0000313|Proteomes:UP000033166};
RN [1] {ECO:0000313|Proteomes:UP000033166}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MKFS47 {ECO:0000313|Proteomes:UP000033166};
RA Andreevskaya M.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Global transcriptional regulator of carbon catabolite
CC repression (CCR) and carbon catabolite activation (CCA), which ensures
CC optimal energy usage under diverse conditions.
CC {ECO:0000256|RuleBase:RU368079}.
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DR EMBL; LN774769; CEN28732.1; -; Genomic_DNA.
DR RefSeq; WP_047915805.1; NZ_LN774769.1.
DR AlphaFoldDB; A0A0D6DY85; -.
DR STRING; 1364.LP2241_30541; -.
DR GeneID; 71635709; -.
DR KEGG; lpk:LACPI_1532; -.
DR HOGENOM; CLU_037628_6_0_9; -.
DR Proteomes; UP000033166; Chromosome I.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProtKB-UniRule.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06298; PBP1_CcpA; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR006377; CcpA.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR001761; Peripla_BP/Lac1_sug-bd_dom.
DR InterPro; IPR028082; Peripla_BP_I.
DR NCBIfam; TIGR01481; ccpA; 1.
DR PANTHER; PTHR30146:SF150; CATABOLITE CONTROL PROTEIN A; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF00532; Peripla_BP_1; 1.
DR PRINTS; PR00036; HTHLACI.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS00356; HTH_LACI_1; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW Activator {ECO:0000256|RuleBase:RU368079};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU368079};
KW Repressor {ECO:0000256|RuleBase:RU368079};
KW Transcription {ECO:0000256|ARBA:ARBA00023163,
KW ECO:0000256|RuleBase:RU368079};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015,
KW ECO:0000256|RuleBase:RU368079}.
FT DOMAIN 6..60
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 332 AA; 36145 MW; 597DF2FD19F4D80B CRC64;
MDNETITIYD VAREAAVSMA TVSRVVNGNQ NVKEATRRKV LDVIERLDYR PNAVARGLAS
KKTTTVGVVI PDISNSYFAS LARGIDDIAT MYKYNIVIAN SDGDDDKEIN VVNTLLAKQV
DGLVFLAHDL SDKIRAEFSR TRTPIVLAGA VDHESQIPSV NIDYKQATKD VTLELAKNNQ
KIALVAGPMV NAINGKERLI GYQAALSESG QTFSEGLVFE TNYSFNDGMK LAERVKASGA
TAAVVTDDEV AVGLLNGLVN NGVNVPEDFE IITANNSVIT EFTRPTLSSI EQPLYDLGAV
SMRLLTKMMH KEEVDEKRVI LPHGIVKRGS TK
//
