ID A0A0D6EU19_9PROT Unreviewed; 208 AA.
AC A0A0D6EU19;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Large ribosomal subunit protein uL4 {ECO:0000256|ARBA:ARBA00035244, ECO:0000256|HAMAP-Rule:MF_01328};
GN Name=rplD {ECO:0000256|HAMAP-Rule:MF_01328,
GN ECO:0000313|EMBL:CEZ19107.1};
GN ORFNames=BN1208_0213 {ECO:0000313|EMBL:CEZ19107.1}, FIT69_01025
GN {ECO:0000313|EMBL:QDD01186.1};
OS Candidatus Methylopumilus planktonicus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Nitrosomonadales;
OC Methylophilaceae; Methylopumilus.
OX NCBI_TaxID=1581557 {ECO:0000313|EMBL:CEZ19107.1, ECO:0000313|Proteomes:UP000064007};
RN [1] {ECO:0000313|Proteomes:UP000064007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMS-10A-171 {ECO:0000313|Proteomes:UP000064007};
RA Salcher M.M.;
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:CEZ19107.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=MMS-10A-171 {ECO:0000313|EMBL:CEZ19107.1};
RA Salcher M Michaela;
RL Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:QDD01186.1, ECO:0000313|Proteomes:UP000314748}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MMS-VB-116 {ECO:0000313|EMBL:QDD01186.1,
RC ECO:0000313|Proteomes:UP000314748};
RA Salcher M., Schaefle D., Kaspar M., Neuenschwander S.M., Ghai R.;
RT "Evolution in action: Habitat-transition from sediment to pelagial leads to
RT genome-streamlining in Methylophilaceae.";
RL ISME J. 0:0-0(2019).
CC -!- FUNCTION: Forms part of the polypeptide exit tunnel.
CC {ECO:0000256|HAMAP-Rule:MF_01328}.
CC -!- FUNCTION: One of the primary rRNA binding proteins, this protein
CC initially binds near the 5'-end of the 23S rRNA. It is important during
CC the early stages of 50S assembly. It makes multiple contacts with
CC different domains of the 23S rRNA in the assembled 50S subunit and
CC ribosome. {ECO:0000256|HAMAP-Rule:MF_01328}.
CC -!- SUBUNIT: Part of the 50S ribosomal subunit. {ECO:0000256|HAMAP-
CC Rule:MF_01328}.
CC -!- SIMILARITY: Belongs to the universal ribosomal protein uL4 family.
CC {ECO:0000256|ARBA:ARBA00010528, ECO:0000256|HAMAP-Rule:MF_01328}.
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DR EMBL; LN827929; CEZ19107.1; -; Genomic_DNA.
DR EMBL; CP040978; QDD01186.1; -; Genomic_DNA.
DR RefSeq; WP_046486959.1; NZ_LN827929.1.
DR AlphaFoldDB; A0A0D6EU19; -.
DR STRING; 1581557.BN1208_0213; -.
DR KEGG; mbat:BN1208_0213; -.
DR HOGENOM; CLU_041575_5_2_4; -.
DR OrthoDB; 9803201at2; -.
DR Proteomes; UP000064007; Chromosome 1.
DR Proteomes; UP000314748; Chromosome.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProtKB-KW.
DR GO; GO:0005840; C:ribosome; IEA:UniProtKB-KW.
DR GO; GO:0019843; F:rRNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
DR GO; GO:0006412; P:translation; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.1370.10; -; 1.
DR HAMAP; MF_01328_B; Ribosomal_L4_B; 1.
DR InterPro; IPR002136; Ribosomal_uL4.
DR InterPro; IPR013005; Ribosomal_uL4-like.
DR InterPro; IPR023574; Ribosomal_uL4_dom_sf.
DR NCBIfam; TIGR03953; rplD_bact; 1.
DR PANTHER; PTHR10746:SF6; 39S RIBOSOMAL PROTEIN L4, MITOCHONDRIAL; 1.
DR PANTHER; PTHR10746; 50S RIBOSOMAL PROTEIN L4; 1.
DR Pfam; PF00573; Ribosomal_L4; 1.
DR SUPFAM; SSF52166; Ribosomal protein L4; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000064007};
KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, ECO:0000256|HAMAP-
KW Rule:MF_01328};
KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, ECO:0000256|HAMAP-
KW Rule:MF_01328}; RNA-binding {ECO:0000256|HAMAP-Rule:MF_01328};
KW rRNA-binding {ECO:0000256|HAMAP-Rule:MF_01328}.
FT REGION 50..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..79
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 208 AA; 23173 MW; 5AB1130AA9BD981A CRC64;
MELKLLDKNG KSAKKSVTVS DATFGREFNE ALVHQLVVAY MANARVATRS QKTRGTVKHS
TRKPYAQKGT GNARSGMTSS PIWRGGGRTF PNSPDENFSH KMNRKAYRVG MRSILSELVR
QERLSIVEEF KLETPKTKQL VDKIKDMGYT QGVLVLTDAF DENLYLSSRN LTNVMVVEAQ
YADPVSLVQF PNVVATAGAL KKLEEMLA
//
