ID A0A0D6KYE1_9CYAN Unreviewed; 903 AA.
AC A0A0D6KYE1;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Sensor histidine kinase {ECO:0000313|EMBL:EKF04481.1};
GN ORFNames=FDUTEX481_01749 {ECO:0000313|EMBL:EKF04481.1};
OS Tolypothrix sp. PCC 7601.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Tolypothrichaceae;
OC Tolypothrix.
OX NCBI_TaxID=1188 {ECO:0000313|EMBL:EKF04481.1, ECO:0000313|Proteomes:UP000032761};
RN [1] {ECO:0000313|EMBL:EKF04481.1, ECO:0000313|Proteomes:UP000032761}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7601 / UTEX B 481 {ECO:0000313|Proteomes:UP000032761};
RX PubMed=25953173;
RA Yerrapragada S., Shukla A., Hallsworth-Pepin K., Choi K., Wollam A.,
RA Clifton S., Qin X., Muzny D., Raghuraman S., Ashki H., Uzman A.,
RA Highlander S.K., Fryszczyn B.G., Fox G.E., Tirumalai M.R., Liu Y., Kim S.,
RA Kehoe D.M., Weinstock G.M.;
RT "Extreme Sensory Complexity Encoded in the 10-Megabase Draft Genome
RT Sequence of the Chromatically Acclimating Cyanobacterium Tolypothrix sp.
RT PCC 7601.";
RL Genome Announc. 3:0-0(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EKF04481.1}.
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DR EMBL; AGCR01000006; EKF04481.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D6KYE1; -.
DR STRING; 1188.FDUTEX481_01749; -.
DR PATRIC; fig|1188.3.peg.1756; -.
DR HOGENOM; CLU_368330_0_0_3; -.
DR Proteomes; UP000032761; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:InterPro.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR CDD; cd00130; PAS; 3.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013656; PAS_4.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR NCBIfam; TIGR00229; sensory_box; 3.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08448; PAS_4; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00086; PAC; 3.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 3.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EKF04481.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 327..400
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 404..456
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 531..579
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 712..901
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 285..337
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 903 AA; 102003 MW; AD847289123F9002 CRC64;
MGKTRPMNYL QKFHLVEAEK ARVLGQFFEA EEFYERAIAL AAENEFIQEE ALAYELAAKH
YLARGRSKIA QTYMKEAHYC YDRWGATAKV KDLEKRYPQL LKTNLVRQSH SIVTDETIRH
PTAAIDLAAV MKAAQAISEM IHLDQLTATL MQVVIENTGA ETGALILLED DRLTVVAQCS
GSRQCNLEKI TVAGCATIPV SVIQSVERTS ETLVFDDAVS EPSFLTDRYI QNQQTRSLLC
MPILKQNQLI GILYLENNLS PGVFTSDRLQ VLKLLIAQAA ISLENARLYE RLSDYSETLE
RKVEEQTQAL QQEIAERQQT EAALRQSEAN YRNLLQTANS VIIRYDPQGR IRYINDYGVK
LLGYEEHQIL GRSLFETIIP ETELSGRDVR PFVHDLLRNP QSYPQGEGEN LCRDGRRVWV
VWSNQAIFNE QGDVVEILSV GNDTTQRRQA EEALQRSEAK FRTIFENSQV GIYRTRTDDG
LILNANQRFA DLFGFDSPQE IIGIEHTIGY WVNPSDRQQG IEVMKRDGEV RSYEAQMRKR
DGTVFWGLFS SYLNAADDYI EGVIADISDR KQAEVALQAS EAELRSLFSA IPDPLCIFTA
QGQLICAIKG NPSYGELHRE EYIGKTLHQL YATGQADEFL SYIQQVLRTQ QVLTVEYSQW
IAGREMWFSA RIAPIRHEQV IWIARDITLQ KRAEAASILE ERNRMAREIH DTLAQAFTGI
LAQVGAAKQV LTDDLEATEA HLDLIKELAR TGLVEARRSV VALRPQLLEE GSLQSALHRL
VAQLRTAAMD TTLYYEIEGA VYSLPTEVES NLLRIGQEAL TNAIRHANAD EIRVELIYDR
DRFCLRVRDN GQGFGVGIIP ASLGFGLLGM SERAERIGAQ LTIRSQPGEG TEMIVTVDQE
ALP
//
