ID A0A0D6TGB2_9RHOB Unreviewed; 624 AA.
AC A0A0D6TGB2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=DNA polymerase III subunit epsilon {ECO:0000313|EMBL:KIX19245.1};
GN ORFNames=SY26_03990 {ECO:0000313|EMBL:KIX19245.1};
OS Paracoccus sp. 228.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Paracoccus.
OX NCBI_TaxID=1192054 {ECO:0000313|EMBL:KIX19245.1, ECO:0000313|Proteomes:UP000032743};
RN [1] {ECO:0000313|EMBL:KIX19245.1, ECO:0000313|Proteomes:UP000032743}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=361 {ECO:0000313|EMBL:KIX19245.1,
RC ECO:0000313|Proteomes:UP000032743};
RA Karczewska-Golec J., Kochanowska-Lyzen M., Balut M., Golec P.,
RA Madanecki P., Markert S., Piotrowski A., Schweder T., Szalewska-Palasz A.;
RT "Three Bacterial Inhabitants of the Baltic Sea under Osmotic Stress: a
RT Genomic and a Proteomic Perspective.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: DNA polymerase III is a complex, multichain enzyme
CC responsible for most of the replicative synthesis in bacteria. The
CC epsilon subunit contain the editing function and is a proofreading 3'-
CC 5' exonuclease. {ECO:0000256|ARBA:ARBA00025483}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIX19245.1}.
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DR EMBL; JYGY01000001; KIX19245.1; -; Genomic_DNA.
DR RefSeq; WP_045999328.1; NZ_JYGY01000001.1.
DR STRING; 1192054.SY26_03990; -.
DR PATRIC; fig|1603292.4.peg.819; -.
DR OrthoDB; 9804290at2; -.
DR Proteomes; UP000032743; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003887; F:DNA-directed DNA polymerase activity; IEA:InterPro.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProt.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd06127; DEDDh; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR006054; DnaQ.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR NCBIfam; TIGR00573; dnaq; 1.
DR PANTHER; PTHR30231; DNA POLYMERASE III SUBUNIT EPSILON; 1.
DR PANTHER; PTHR30231:SF4; PROTEIN NEN2; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032743};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 34..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 432..599
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
SQ SEQUENCE 624 AA; 65957 MW; D7B0784D250FC1C4 CRC64;
MRRRILMLFL AALVAALVLA GLALWRVVQG GQDAVIQAAM IAGLGLLGLM TALWFLFDRH
LARPLESLAG ALRTGRVPDL AQTRHLADLG PAARDAALAR ERSDHALAQA LQDHAAETLR
EKASLEAILA DFGAGAVMAD ARGRVVFYNA SAARLLPGLA LDRALDTLLT SGALRAAQMR
LSAGAAATDL TCLTVGGVRL SGRLRAIDDG LLLILRDGVV QRPAPRDTLE ALRRHASTLV
PMLDALDGPI PPALAQAIRA EGQGLANATR SLSRIMASDA PGTVAALTEL AAGLEAADLP
PXAFRAEAAS LNALLLLLDA RLRAVGHTPV LSVRPDPDDQ MRLVLDWRGS PVPIDLLEGW
LTAAPDPGQP DVTGAEILAR HGTGIWPETD GARARLVMPL ALAQGVADGS GVTYDFALAT
RGAASSRLAD LTCVVFDTET TGLTDRDRIV QIAGLRLARG RLTGERFETL VNPGCPIPPS
STAIHHITDA MVADAPDLTA ALTAFRHFCD DSVLIAHNAP FDMGFLRRAE AQTGTRFDNR
VLDTVLLSAM VWGQSEVHTL DALTERLGIA IPPEARHTAM GDTIATAQAY LALIPALEAK
GITRFEEVVA KARDHRALIA DANR
//
