ID A0A0D6TLZ7_9FLAO Unreviewed; 2334 AA.
AC A0A0D6TLZ7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Insecticide toxin TcdB middle/N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SY27_10270 {ECO:0000313|EMBL:KIX21138.1};
OS Flavobacterium sp. 316.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1603293 {ECO:0000313|EMBL:KIX21138.1, ECO:0000313|Proteomes:UP000032747};
RN [1] {ECO:0000313|EMBL:KIX21138.1, ECO:0000313|Proteomes:UP000032747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=316 {ECO:0000313|EMBL:KIX21138.1,
RC ECO:0000313|Proteomes:UP000032747};
RA Karczewska-Golec J., Kochanowska-Lyzen M., Balut M., Golec P.,
RA Madanecki P., Markert S., Piotrowski A., Schweder T., Szalewska-Palasz A.;
RT "Three Bacterial Inhabitants of the Baltic Sea under Osmotic Stress: a
RT Genomic and a Proteomic Perspective.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIX21138.1}.
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DR EMBL; JYGZ01000004; KIX21138.1; -; Genomic_DNA.
DR RefSeq; WP_045969881.1; NZ_JYGZ01000004.1.
DR STRING; 1603293.SY27_10270; -.
DR PATRIC; fig|1603293.4.peg.2123; -.
DR OrthoDB; 6225685at2; -.
DR Proteomes; UP000032747; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016798; F:hydrolase activity, acting on glycosyl bonds; IEA:InterPro.
DR Gene3D; 2.40.128.340; -; 1.
DR Gene3D; 2.180.10.10; RHS repeat-associated core; 3.
DR InterPro; IPR003305; CenC_carb-bd.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR029115; Ntox23.
DR InterPro; IPR022385; Rhs_assc_core.
DR InterPro; IPR003284; Sal_SpvB.
DR InterPro; IPR006530; YD.
DR NCBIfam; TIGR03696; Rhs_assc_core; 1.
DR NCBIfam; TIGR01643; YD_repeat_2x; 1.
DR PANTHER; PTHR46580:SF3; ATP_GTP-BINDING PROTEIN-RELATED; 1.
DR PANTHER; PTHR46580; SENSOR KINASE-RELATED; 1.
DR Pfam; PF02018; CBM_4_9; 1.
DR Pfam; PF13517; FG-GAP_3; 1.
DR Pfam; PF15528; Ntox23; 1.
DR Pfam; PF03534; SpvB; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032747};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..2334
FT /note="Insecticide toxin TcdB middle/N-terminal domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002314139"
FT TRANSMEM 2007..2027
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 2039..2059
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1644..1768
FT /note="CBM-cenC"
FT /evidence="ECO:0000259|Pfam:PF02018"
FT DOMAIN 2103..2302
FT /note="Bacterial toxin 23"
FT /evidence="ECO:0000259|Pfam:PF15528"
FT REGION 44..73
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 45..73
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2334 AA; 260337 MW; 6172F6D73C4C92CF CRC64;
MKKLLLLITI LLNLVCFSQD ELGGTPVEGI IPIKRIESIE KDGNIKANQQ KTNESTTLTP
SSPTGSSEEV GVTEGQLSVS LTGGATYSIP IAVPPGINGI VPQIALNYNS QGGNGLAGYG
WNISGVSVIT RIPSTKFHDN TIDAVDFDNL DRFAFDGQRL IVKNETAGVY GANGTIYETE
GYSNIQITSY GAHPSGPNFG PAYFVVQYPD GSIAHYGNST NSRSLTDWAI TYWQNPQGVR
ISYNYTLSNN SLSINTIKYG SRLTTTPINE ISFVYKTRQR PEQAYIGNQI FLSSTILSEI
KVKGNNIGFR NYLLSHEITS LGYERLKSIT EKSGDNSKSF NPTVFNYDTT SENINFSPNA
TTINVNNVKS DNSATISGDF DGDGEMDFLL YPTTGSDAKK KYWLYSNINS NNLNIGYEHN
IGSFQEIFPI SWLGGGASLG YKLMPQQGWC AIQYDASSNI TTFKNYSTGT VSPIYFQYEK
TFEFPQLIYY SEHPRSCISP RPPIQHIQNI AKEYVNGDFN GDGLTDVLII EKDTQYTYDG
PCDLDGNLVS YTRNRTGNAY FLDLDRRLTN NYINIAGQLH ITGLDKLVVA DFNGDGKSDI
FVFNTGVVRI YTLDDNNYLT LITTRNNPNI SLTYPIYMGD YNGDGKADFI TPTANNSSIF
SKFLSTGTDV TLSMIDLGAA SYYQGAYDGN TSVVQYIIPN DFNNDGKTDL IFAKSVYKTS
GEVNNVSQNR FISVRYLHNK AENEFESVMF TTMIDVYGLN HFPIPVSLSF DKANANKQIS
FISNNNIYSA ISLKDNLIDV LLKEVVLGNG VKEVISYQSL NYDPTSYENA FQPSSYTANY
PNFDIEVANN FRVVSKLEQI SATQYKKQKF KYYGAVTNVE GLGFVGFRGL ARTNWFNDDN
PVISSVSKHD ITKRGAVSET YSVLGETYGN FTSNSPTSFI NKINMTYVDE LLANKVFKIN
NSVTISANGL EGTFKETTTT YDTYNNPLTT TAISKNGSTI ESTEVVNIEY FPVVTSPTYI
VGRLKKKNSS VTHNGDTMTG EEIYEYNSDH LVSKTQKKGH NTNYLTEENI YDVFGNITQK
KISAIGLTPR ITNFTYDTTG RFLTSNTDIE GLITSYTYNT SNGLLLTQTL PSILGYSLTT
TYLYDLWGKK IKETDYLGKS LNYFYGWLSP GSSGFLATRV SGDDNSESFV WYDDLGRKIA
EGLRTINDSN SSESANNWKT FELDIYDRVK KIYEPQLSGF PQWSGLFSTT TYDTYGRTTQ
VVEPTGKTTT INYSGLTTTT SDGVSNTASI KNSLGSIISM TDNGGTITYD YFANGNLKKS
IINGLETIIE QDGWGRKTKL TDPSAGIYEY AYNDLGEMTM EITPNGQTNY KYDDFGKLKE
KTITGLNTNS KETFTYNNTT KLLTNSKFED FINDVVNIHA YGYDTYKRLN YKTEEISTSL
LPLAYYQQDF NFDSFGRAEK QSYLMINLAD SKNSFKEVKN TYKNGYHWQI LDAVSNQVLW
QTNEVNERGQ LTSANYGNGL ALNKSYDQYG YIQRSRVFTA VSPNTDVLNL YTTFEPQRGN
LTSRTNSLFN WTENFEYDTL DRLTHYTNAQ GIQVEQIYEN DGRIKENTLG QYNYSNSDKR
YQHTSIDINP SSKAYYQNRL GLFNDNMEQK LGWQIYEPSV FSFDSTVSHI TGSSSLKIAN
TSATEKVVHS ENWIAIDNAV PTEYTYSVWV KSDGTNPEAE IFLFMKTANE TGYYTLVDSK
IVNTSTDWVQ IEKTFLVPAS IKKLNIRLDN NATGVLWFDD VRIRKTSDAA PIERELNISY
NTWKSPYEIE ETGVDKISFI YNQMNKRSSM FYGGLQADKM ERQYRKHYSA DGSMEIKHNT
ATGEVEFITY IGGDGYSAPV VLKSDGTTQE YLYLHRDYLG SIIAITNQAG SVVEKRLFDA
WGEVIKVVDG QDTILTGFAV LDRGYTGHEH LQSVALIHMN GRLYDAKLHR FLQSDNFVSD
PHNTQAFNRY SYVLNNPLKY SDVSGELPVL VAAAIIGAFI GGASYVAHAI QTGNWSWGGF
GIAVGVGAVV GVIAPQAIFS AGSIGELVIS SFASGFMPAI NIPINDHITL SASPSIAFGN
AGGAGVSYGV TFSDGDFSIS GGYGIMEYSN YNGFGANSRE FRYSALVSYD DGKTGFSLGT
NFWRGDFKQR TTYLGFRNGD FRFGYENDGS PFSYAGKVLS NNTDMYRTAA ASVGIGGFDL
QLNMFTGRSG NDTGKGRKNE RNSEFVDLDN GRFKKDRRLG LWKNSEADAY RLGALSVGYK
GYKVGVNSEY VRDVFQNWFA HKILSPQPGF RMLSNNWNGY FQYNTPMINK ATLW
//
