ID A0A0D6TPL1_9FLAO Unreviewed; 640 AA.
AC A0A0D6TPL1;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:KIX21717.1};
GN ORFNames=SY27_08530 {ECO:0000313|EMBL:KIX21717.1};
OS Flavobacterium sp. 316.
OC Bacteria; Bacteroidota; Flavobacteriia; Flavobacteriales;
OC Flavobacteriaceae; Flavobacterium.
OX NCBI_TaxID=1603293 {ECO:0000313|EMBL:KIX21717.1, ECO:0000313|Proteomes:UP000032747};
RN [1] {ECO:0000313|EMBL:KIX21717.1, ECO:0000313|Proteomes:UP000032747}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=316 {ECO:0000313|EMBL:KIX21717.1,
RC ECO:0000313|Proteomes:UP000032747};
RA Karczewska-Golec J., Kochanowska-Lyzen M., Balut M., Golec P.,
RA Madanecki P., Markert S., Piotrowski A., Schweder T., Szalewska-Palasz A.;
RT "Three Bacterial Inhabitants of the Baltic Sea under Osmotic Stress: a
RT Genomic and a Proteomic Perspective.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIX21717.1}.
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DR EMBL; JYGZ01000003; KIX21717.1; -; Genomic_DNA.
DR RefSeq; WP_045969152.1; NZ_JYGZ01000003.1.
DR AlphaFoldDB; A0A0D6TPL1; -.
DR STRING; 1603293.SY27_08530; -.
DR PATRIC; fig|1603293.4.peg.1770; -.
DR OrthoDB; 9766847at2; -.
DR Proteomes; UP000032747; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0009002; F:serine-type D-Ala-D-Ala carboxypeptidase activity; IEA:InterPro.
DR GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR InterPro; IPR017790; Penicillin-binding_protein_2.
DR NCBIfam; TIGR03423; pbp2_mrdA; 1.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000032747};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 5..23
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 47..209
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 247..577
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 640 AA; 72425 MW; CFC7289CD5C6EFC8 CRC64;
MRKIILPLII IITAIILIAR IFYLQVINDS LKLQSENNAI KKVFDFPERG YIYDRNGKLL
VANQPSYDIM VVPREMKNID TLDLCNLLNI TKEDFIKKIK KAIVYSPRLP SVFLSQLNKK
EYAAFQEKER KFEGFYTQKR ALRDYQVKEG ANIFGFITQV NEGIIAKNPY YNSGDLIGRQ
GVEQEYEEIL RGVKGIKYLL RDKHNKIIGP YKNGKFDTIS QQGKDLTLTI DSELQKYGTD
LMINKRGGIV AIEPKTGEIL ALVSAPTYDP ALLVGRQRSK NYTELYHDSI AKPLYDRGLQ
AQYPPGSPFK IITGLIGLQE EVIDEETGFV CHRGFSYGRG AFMKCHDAGI SKLNNGIYQS
CNTYFANVFK RSIDKYPNPS MSIDKWAEHV KSFGLGEFLG TDLPIGAKGL IPTSKTYQRA
YPNGGWRSTT IISNSIGQGE ILTTPLQLAN MMAVVANKGY YYTPHIVKNI KGSELDKKYT
TKHESTIDPK YFEPMIEGLA NVYNSPGGTA RTLKVKDMEI CGKTGTAENK IRVAGKTYQL
KDHSIFVAFA PKENPTIAIA VFVENGYWGT RWAGPIATLM VEKYINKKIT RKDLETRMLN
GSLQDEYKKI ENIIRQRFPE PSKVEDSTTK TIARKEEVVN
//
