ID A0A0D6UBL9_LACRH Unreviewed; 185 AA.
AC A0A0D6UBL9; A0A2A5L6U7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 61.
DE RecName: Full=Ribosome hibernation promoting factor {ECO:0000256|HAMAP-Rule:MF_00839};
DE Short=HPF {ECO:0000256|HAMAP-Rule:MF_00839};
GN Name=raiA {ECO:0000313|EMBL:NZA04853.1};
GN Synonyms=hpf {ECO:0000256|HAMAP-Rule:MF_00839};
GN ORFNames=BGK71_04255 {ECO:0000313|EMBL:ASX16643.1}, CCE29_02555
GN {ECO:0000313|EMBL:ART94957.1}, FOS38_02170
GN {ECO:0000313|EMBL:MBB1163761.1}, GFB59_04795
GN {ECO:0000313|EMBL:QPB47201.1}, H0N82_06960
GN {ECO:0000313|EMBL:NZA04853.1}, HWN39_03630
GN {ECO:0000313|EMBL:NVO87588.1}, PY91_02025
GN {ECO:0000313|EMBL:OAU25123.1};
OS Lacticaseibacillus rhamnosus (Lactobacillus rhamnosus).
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lacticaseibacillus.
OX NCBI_TaxID=47715 {ECO:0000313|EMBL:NZA04853.1, ECO:0000313|Proteomes:UP000552935};
RN [1] {ECO:0000313|EMBL:OAU25123.1, ECO:0000313|Proteomes:UP000078528}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lrh22 {ECO:0000313|EMBL:OAU25123.1,
RC ECO:0000313|Proteomes:UP000078528};
RA Ceapa C., Ritari J.;
RT "The variable regions of Lactobacillus rhamnosus genomes reveal the dynamic
RT evolution of metabolic and host-adaptation repertoires.";
RL Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:ASX16643.1, ECO:0000313|Proteomes:UP000215843}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LR5 {ECO:0000313|EMBL:ASX16643.1,
RC ECO:0000313|Proteomes:UP000215843};
RA Nam Y.-D., Kang J., Chung W.-H.;
RT "Complete genome sequence of Lactobacillus rhamnosus LR5.";
RL Submitted (AUG-2016) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|EMBL:ART94957.1, ECO:0000313|Proteomes:UP000195731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=4B15 {ECO:0000313|EMBL:ART94957.1,
RC ECO:0000313|Proteomes:UP000195731};
RA Oh N.-S.;
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
RN [4] {ECO:0000313|EMBL:MBB1163761.1, ECO:0000313|Proteomes:UP000551634}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DPC 7102 {ECO:0000313|EMBL:MBB1163761.1,
RC ECO:0000313|Proteomes:UP000551634};
RA Leeuwendaal N., Stanton C., O'Toole P.W., Beresford T.;
RT "Annotated Genomes of Lactobacillus rhamnosus DPC 7102 and Lactobacillus
RT paracasei DCP 7150.";
RL Submitted (JUL-2019) to the EMBL/GenBank/DDBJ databases.
RN [5] {ECO:0000313|EMBL:QPB47201.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=TK-F8B {ECO:0000313|EMBL:QPB47201.1};
RA Chen H.;
RT "Whole genome of Lactobacillus rhamnosus TK-F8B.";
RL Submitted (OCT-2019) to the EMBL/GenBank/DDBJ databases.
RN [6] {ECO:0000313|EMBL:NVO87588.1, ECO:0000313|Proteomes:UP000542889}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=QC {ECO:0000313|EMBL:NVO87588.1,
RC ECO:0000313|Proteomes:UP000542889};
RA Yi H., Jin M.;
RT "Lactobacillus rhamnosus QC,genome.";
RL Submitted (JUN-2020) to the EMBL/GenBank/DDBJ databases.
RN [7] {ECO:0000313|EMBL:NZA04853.1, ECO:0000313|Proteomes:UP000552935}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AMC0712 {ECO:0000313|EMBL:NZA04853.1,
RC ECO:0000313|Proteomes:UP000552935};
RA Marsh A.J., Azcarate-Peril M.A.;
RT "Organ Donor 1.";
RL Submitted (JUL-2020) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Required for dimerization of active 70S ribosomes into 100S
CC ribosomes in stationary phase; 100S ribosomes are translationally
CC inactive and sometimes present during exponential growth.
CC {ECO:0000256|HAMAP-Rule:MF_00839}.
CC -!- SUBUNIT: Interacts with 100S ribosomes. {ECO:0000256|HAMAP-
CC Rule:MF_00839}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00839}.
CC -!- SIMILARITY: Belongs to the HPF/YfiA ribosome-associated protein family.
CC Long HPF subfamily. {ECO:0000256|HAMAP-Rule:MF_00839}.
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DR EMBL; CP021426; ART94957.1; -; Genomic_DNA.
DR EMBL; CP017063; ASX16643.1; -; Genomic_DNA.
DR EMBL; VLHP01000002; MBB1163761.1; -; Genomic_DNA.
DR EMBL; JABXWP010000004; NVO87588.1; -; Genomic_DNA.
DR EMBL; JACCKI010000004; NZA04853.1; -; Genomic_DNA.
DR EMBL; JTIH01000002; OAU25123.1; -; Genomic_DNA.
DR EMBL; CP045586; QPB47201.1; -; Genomic_DNA.
DR RefSeq; WP_005684485.1; NZ_WPCQ01000007.1.
DR STRING; 47715.AWJ15_00355; -.
DR GeneID; 69831388; -.
DR eggNOG; COG1544; Bacteria.
DR OMA; KYFAMPP; -.
DR OrthoDB; 9794975at2; -.
DR Proteomes; UP000078528; Unassembled WGS sequence.
DR Proteomes; UP000195731; Chromosome.
DR Proteomes; UP000215843; Chromosome.
DR Proteomes; UP000542889; Unassembled WGS sequence.
DR Proteomes; UP000551634; Unassembled WGS sequence.
DR Proteomes; UP000552935; Unassembled WGS sequence.
DR Proteomes; UP000663681; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0044238; P:primary metabolic process; IEA:InterPro.
DR GO; GO:0006417; P:regulation of translation; IEA:UniProtKB-UniRule.
DR CDD; cd00552; RaiA; 1.
DR Gene3D; 3.30.160.100; Ribosome hibernation promotion factor-like; 1.
DR Gene3D; 3.30.505.50; Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain; 1.
DR HAMAP; MF_00839; HPF; 1.
DR InterPro; IPR034694; HPF_long/plastid.
DR InterPro; IPR036567; RHF-like.
DR InterPro; IPR003489; RHF/RaiA.
DR InterPro; IPR032528; Ribosom_S30AE_C.
DR InterPro; IPR038416; Ribosom_S30AE_C_sf.
DR NCBIfam; TIGR00741; yfiA; 1.
DR PANTHER; PTHR33231; 30S RIBOSOMAL PROTEIN; 1.
DR PANTHER; PTHR33231:SF1; 30S RIBOSOMAL PROTEIN; 1.
DR Pfam; PF16321; Ribosom_S30AE_C; 1.
DR Pfam; PF02482; Ribosomal_S30AE; 1.
DR SUPFAM; SSF69754; Ribosome binding protein Y (YfiA homologue); 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00839};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845, ECO:0000256|HAMAP-
KW Rule:MF_00839}.
FT DOMAIN 126..180
FT /note="Sigma 54 modulation/S30EA ribosomal protein C-
FT terminal"
FT /evidence="ECO:0000259|Pfam:PF16321"
SQ SEQUENCE 185 AA; 21090 MW; CA6C4B387789E708 CRC64;
MLTYNVRGEN IEVTEAIRNY VEKRISKLNK FFGGSVTATA HVNLKVYPDK TAKVEVTIPL
SFLTLRAEET SPDLYASIDL VTDKLERQVR KFKTKINRKS REKGFGQIDI DSNAPAEPKP
AEDDDNLKVV RTKRVSLKPM DSQEAILQMD MLGHNFFIFE DADTNGTSIV YKRRDGRYGL
IETNE
//
