ID A0A0D6X8Y1_THEFI Unreviewed; 576 AA.
AC A0A0D6X8Y1;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Penicillin-binding protein {ECO:0000313|EMBL:KIX84369.1};
GN ORFNames=THFILI_09770 {ECO:0000313|EMBL:KIX84369.1};
OS Thermus filiformis.
OC Bacteria; Deinococcota; Deinococci; Thermales; Thermaceae; Thermus.
OX NCBI_TaxID=276 {ECO:0000313|EMBL:KIX84369.1, ECO:0000313|Proteomes:UP000030364};
RN [1] {ECO:0000313|EMBL:KIX84369.1, ECO:0000313|Proteomes:UP000030364}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 43280 {ECO:0000313|EMBL:KIX84369.1,
RC ECO:0000313|Proteomes:UP000030364};
RA Mandelli F., Ramires B.O., Paixao D.A., Camilo C.M., Polikarpov I.,
RA Couger M.B., Prade R., Riano-Pachon D.M., Squina F.M.;
RT "Draft Genome Sequence of the thermophile Thermus filiformis ATCC43280
RT producer of carotenoid-(di)glucoside-branched fatty acids (di)esters.";
RL Submitted (FEB-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIX84369.1}.
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DR EMBL; JPSL02000040; KIX84369.1; -; Genomic_DNA.
DR RefSeq; WP_045246422.1; NZ_JPSL02000040.1.
DR AlphaFoldDB; A0A0D6X8Y1; -.
DR STRING; 276.THFILI_09770; -.
DR OrthoDB; 9804124at2; -.
DR Proteomes; UP000030364; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF2; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE MRDA; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136}.
FT DOMAIN 97..198
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 250..569
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 576 AA; 63018 MW; F33321E9E5E35C44 CRC64;
MTSRIRALIL FFALVFAMYG ARLWQLQVVE YERYATKSQG NYLKTEGLPA PRGRLLDRKG
RVLAQDRVAV DLVYEGGEVL YKERILALLG LSGLPKAQGP VTLKAGVPEA LVPTLAELTA
GQKNLYLVER IQRVYPRPIS GPVLGYVRRA GPEEVKRGYS PDEEVGAAGL EAALEPFLRG
VRGVRAVEMN VRGERLREEI LKEPTPGKDV VLTLDLDLQR AAEKALEEAL ADINRGRALN
GLPPARRVKG AIVALDPRTG EVLAMATAPS FDPNLLARRP VPQEAQALFT DPDLPLLNRA
TQAYTPGSTF KLATSYALLE EGYAAPGTTY RCSPYIVHGG LLRRNWAGRD MGPMTVKEAI
AWSCNTWYYQ AVLKDPLGFV DRLAYRARLL GLGEGTGLEV AEKTGLLPTR AWKQAALKEP
WYPGETLSIA IGQGYVLASP AQIARMLATL ANGGLKPRLH LVKRIGQEEV RYDPERVPGR
YWTTLQEGLR LTVKAGTASF LLKDFPVPTG GKTGTAETPG KRRGLEHAWY MGYGPAEPGT
PYPPLVVVAF FENGGEGSRV ALPAAKKVMA AYWKVE
//
