ID A0A0D6XTC3_9STAP Unreviewed; 1042 AA.
AC A0A0D6XTC3;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE SubName: Full=AcrB/AcrD/AcrF family protein {ECO:0000313|EMBL:SUM58190.1};
DE SubName: Full=Multidrug transporter {ECO:0000313|EMBL:KIX91103.1};
GN Name=swrC {ECO:0000313|EMBL:SUM58190.1};
GN ORFNames=NCTC13832_01938 {ECO:0000313|EMBL:SUM58190.1}, TP70_03935
GN {ECO:0000313|EMBL:KIX91103.1};
OS Staphylococcus microti.
OC Bacteria; Bacillota; Bacilli; Bacillales; Staphylococcaceae;
OC Staphylococcus.
OX NCBI_TaxID=569857 {ECO:0000313|EMBL:KIX91103.1, ECO:0000313|Proteomes:UP000032366};
RN [1] {ECO:0000313|EMBL:KIX91103.1, ECO:0000313|Proteomes:UP000032366}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 22147 {ECO:0000313|EMBL:KIX91103.1,
RC ECO:0000313|Proteomes:UP000032366};
RA Guo J.;
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:SUM58190.1, ECO:0000313|Proteomes:UP000254100}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCTC13832 {ECO:0000313|EMBL:SUM58190.1,
RC ECO:0000313|Proteomes:UP000254100};
RG Pathogen Informatics;
RA Doyle S.;
RL Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; JXWY01000031; KIX91103.1; -; Genomic_DNA.
DR EMBL; UHDT01000001; SUM58190.1; -; Genomic_DNA.
DR RefSeq; WP_044359606.1; NZ_UHDT01000001.1.
DR AlphaFoldDB; A0A0D6XTC3; -.
DR STRING; 569857.TP70_03935; -.
DR PATRIC; fig|569857.6.peg.987; -.
DR OrthoDB; 9757876at2; -.
DR Proteomes; UP000032366; Unassembled WGS sequence.
DR Proteomes; UP000254100; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF0; SWARMING MOTILITY PROTEIN SWRC; 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 355..374
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 381..401
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 455..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 487..514
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 545..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 870..889
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 896..916
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 922..947
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 968..987
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 999..1025
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 249..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1042 AA; 113353 MW; 818FC45551B40D63 CRC64;
MVKKLIDFSL SNKFAIMLMV LLVILGGVFA SFKMKLELLP DTEPPMLTIT TTMPGATPET
VMKEVSDPID EAIRGMSDVS SVKTESLANA SLITVKFNEQ TDMDRAEQDI DKVLKKLEFE
EGVEKPEIQR NSLYAFPVVA YSILHENNDI KQSTQDVENN LIPKLQEIDG VQRATVNGQT
SRRVNIEFDD KKLGTAGLNQ KQVIDYIEAA TKEVPLGLFQ FGDTEKSIVI DGQFASVDAL
KKMEIPLSIA QQQSDDSEGA SAPSPSSQTN ASQQQSIPLQ DVAKVTLADE RESISRTNGK
DAVDIQIIKA QDANTVAVAK EVDKTIQQFV DERKDLKAVQ IMDTAKPIQD SLNTMIEKAL
IGSIVAVIVI MLFLRNFRMT AISIVSIPLS LLIAMVALKL TDVSLNILTL GALTVAIGRV
IDDSIVVIEN IYRRLTRSDE PLSGDHLIVS ATKEVFIPIM SSTIVTIVVF APLAFVTGMV
GQMFRPFAYA VTFSLLASLL VSITIVPVLG SVFFKRGLPK KTTAHVGVVG QRYKRILGWS
LDHKWIVMLI STFLLIASIG LGVMKVGTSF ISAGDNKFMA LTYSPKPGET EENVLKHAEA
VERYLQKNKY VENVQYSVGG ASPVDPTGST NSMALMVQYD TQTPNFDEEP ERVLDHIKTF
KHPGDWKNLD MSTGATSNEL NVQVTGPSPE RLEGTVNKIT KMMQNIDGLT NVKADLAETY
EQYQVKVDSD KAGEYGITAG QLAMMLNANI PDTTVSKVKE DAQTYDVVVK QKKETEWTQQ
KLEQTPIPSA SGEIVTLSDI ATLEKSSTPN KLIKEGGDYA TTIKGTISGD DVGAVSQDVM
KGLNKIDKPN DVKTSLGGTN EDIESAFSQL MLAMLAAILI VYLVLVLTFK GGLAPFTILF
SLPYTVIGVV LALIFTGETL SVPSMIGMLM LIGIVVTNAI VLIDRVINNE AAGMPMKEAL
LEAGGTRIRP ILMTAIATIG ALIPLLFGQD NSVLISKGLA ATVIGGLLSS TLLTLIVVPV
IYEVLFTLKK RLTKKSENID VR
//
