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Database: UniProt
Entry: A0A0D6Z4R6_9BACI
LinkDB: A0A0D6Z4R6_9BACI
Original site: A0A0D6Z4R6_9BACI 
ID   A0A0D6Z4R6_9BACI        Unreviewed;       446 AA.
AC   A0A0D6Z4R6;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   31-JUL-2019, entry version 21.
DE   RecName: Full=Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex {ECO:0000256|RuleBase:RU003423};
DE            EC=2.3.1.- {ECO:0000256|RuleBase:RU003423};
GN   ORFNames=UB32_18455 {ECO:0000313|EMBL:KIY20572.1};
OS   Bacillus subterraneus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=285983 {ECO:0000313|EMBL:KIY20572.1, ECO:0000313|Proteomes:UP000032512};
RN   [1] {ECO:0000313|EMBL:KIY20572.1, ECO:0000313|Proteomes:UP000032512}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MITOT1 {ECO:0000313|EMBL:KIY20572.1,
RC   ECO:0000313|Proteomes:UP000032512};
RA   Peet K.C., Thompson J.R.;
RT   "Draft genome sequences of the supercritical CO2 tolerant bacteria
RT   Bacillus subterraneus MITOT1 and Bacillus cereus MIT0214.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=(R)-lipoate; Xref=ChEBI:CHEBI:83088;
CC         Evidence={ECO:0000256|RuleBase:RU003423};
CC   -!- SIMILARITY: Belongs to the 2-oxoacid dehydrogenase family.
CC       {ECO:0000256|RuleBase:RU003423}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KIY20572.1}.
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DR   EMBL; JXIQ01000195; KIY20572.1; -; Genomic_DNA.
DR   RefSeq; WP_044396566.1; NZ_JXIQ01000195.1.
DR   EnsemblBacteria; KIY20572; KIY20572; UB32_18455.
DR   PATRIC; fig|285983.3.peg.3259; -.
DR   OrthoDB; 1626282at2; -.
DR   BioCyc; GCF_000934845:G1EKL-2964-MONOMER; -.
DR   Proteomes; UP000032512; Unassembled WGS sequence.
DR   GO; GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.559.10; -; 1.
DR   Gene3D; 4.10.320.10; -; 2.
DR   InterPro; IPR003016; 2-oxoA_DH_lipoyl-BS.
DR   InterPro; IPR001078; 2-oxoacid_DH_actylTfrase.
DR   InterPro; IPR000089; Biotin_lipoyl.
DR   InterPro; IPR023213; CAT-like_dom_sf.
DR   InterPro; IPR036625; E3-bd_dom_sf.
DR   InterPro; IPR004167; PSBD.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   Pfam; PF00198; 2-oxoacid_dh; 1.
DR   Pfam; PF00364; Biotin_lipoyl; 1.
DR   Pfam; PF02817; E3_binding; 2.
DR   SUPFAM; SSF47005; SSF47005; 2.
DR   SUPFAM; SSF51230; SSF51230; 1.
DR   PROSITE; PS50968; BIOTINYL_LIPOYL; 1.
DR   PROSITE; PS00189; LIPOYL; 1.
DR   PROSITE; PS51826; PSBD; 2.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003423};
KW   Complete proteome {ECO:0000313|Proteomes:UP000032512};
KW   Lipoyl {ECO:0000256|RuleBase:RU003423, ECO:0000256|SAAS:SAAS00065550};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032512};
KW   Transferase {ECO:0000256|RuleBase:RU003423}.
FT   DOMAIN        2     77       Lipoyl-binding. {ECO:0000259|PROSITE:
FT                                PS50968}.
FT   DOMAIN      129    166       Peripheral subunit-binding (PSBD).
FT                                {ECO:0000259|PROSITE:PS51826}.
FT   DOMAIN      171    208       Peripheral subunit-binding (PSBD).
FT                                {ECO:0000259|PROSITE:PS51826}.
FT   REGION       78    113       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS     87    102       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   446 AA;  48779 MW;  387B906741171779 CRC64;
     MAKEVFMPKL SSTMQVGTLL QWFKEEGDSV EVGEPLFEIM TDKINIEVEA YEEGILLKRY
     FDEDAEVPVN HVVGFIGEEG EKVPDSPPGE SSSSIQTVEQ SDLNNEEAKR KSTEPIIEIE
     ERESGEKVRA TPAARKLAGK EGVRLFDVSG SGPNGRIHVE DVIDYLRSSP KATPLAKKVA
     DDKGIDISQI AGTGPNGKIY RSDVEGNEVV PSTDEGTDSK RVKLDNIGKV VAKRMVESAL
     TAPHVTITTE IDMTETISMR KQLLDKIEKK NGYRLSYTEI IMKAVAYTLK KHPIVNASLQ
     DDEIVMHKAI NIGLGVAVGN GLLVPVVKHV DQKGLARLTE ECKTLGREAR DNKLNPNSMS
     GGTFTISNLG MYAVDTFTPI INQPESAILG VGRINDKPVG INGEIKLRPM MTLSLSFDHR
     IINGAPAAAF LTDLKTVLEQ PFELLV
//
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