ID A0A0D7A0M2_9AGAR Unreviewed; 805 AA.
AC A0A0D7A0M2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Glycoside hydrolase family 5 protein {ECO:0000313|EMBL:KIY42944.1};
GN ORFNames=FISHEDRAFT_68260 {ECO:0000313|EMBL:KIY42944.1};
OS Fistulina hepatica ATCC 64428.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Fistulinaceae; Fistulina.
OX NCBI_TaxID=1128425 {ECO:0000313|EMBL:KIY42944.1, ECO:0000313|Proteomes:UP000054144};
RN [1] {ECO:0000313|EMBL:KIY42944.1, ECO:0000313|Proteomes:UP000054144}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 64428 {ECO:0000313|EMBL:KIY42944.1,
RC ECO:0000313|Proteomes:UP000054144};
RX PubMed=25683379; DOI=10.1016/j.fgb.2015.02.002;
RA Floudas D., Held B.W., Riley R., Nagy L.G., Koehler G., Ransdell A.S.,
RA Younus H., Chow J., Chiniquy J., Lipzen A., Tritt A., Sun H., Haridas S.,
RA LaButti K., Ohm R.A., Kues U., Blanchette R.A., Grigoriev I.V., Minto R.E.,
RA Hibbett D.S.;
RT "Evolution of novel wood decay mechanisms in Agaricales revealed by the
RT genome sequences of Fistulina hepatica and Cylindrobasidium torrendii.";
RL Fungal Genet. Biol. 76:78-92(2015).
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 5 (cellulase A) family.
CC {ECO:0000256|ARBA:ARBA00005641}.
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DR EMBL; KN882150; KIY42944.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D7A0M2; -.
DR OrthoDB; 69117at2759; -.
DR Proteomes; UP000054144; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro.
DR GO; GO:1901136; P:carbohydrate derivative catabolic process; IEA:UniProt.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProt.
DR Gene3D; 3.20.20.80; Glycosidases; 2.
DR Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR InterPro; IPR041036; GH5_C.
DR InterPro; IPR001547; Glyco_hydro_5.
DR InterPro; IPR013780; Glyco_hydro_b.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR31308; -; 1.
DR PANTHER; PTHR31308:SF1; PROTEIN, PUTATIVE-RELATED; 1.
DR Pfam; PF00150; Cellulase; 1.
DR Pfam; PF18564; Glyco_hydro_5_C; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KIY42944.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054144};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 780..803
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 147..328
FT /note="Glycoside hydrolase family 5"
FT /evidence="ECO:0000259|Pfam:PF00150"
FT DOMAIN 647..757
FT /note="Glycoside hydrolase family 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF18564"
SQ SEQUENCE 805 AA; 90743 MW; FCC3613AFF3B7A9E CRC64;
MVSQLQVDLS YETKVFGGVA AVDIDANVVQ LAFKATCHRE MRKIDTIDDK KKKIKKMELR
SQSSHPFLDP SYHPGATPSY AHDWSPQSTG GLRIHGRHFI DKYGRVCQLR GVNVSGSCKT
PINHDDDTFP HDHRFATFVG RPFPIDEAPE HLARLRRWGL TFVRFLVTWE AIEHDGPGMY
DAEYLAYLRE LLSLFPKYGI LTMVNMHQDV WSRFTGGSGA PAWTVEAVGF DLHALEETHA
AFLKGVKGGG HHESERGIWP CGYQKLSAAT MATCFWAGDT FAPKLLIDGV PVQTYLQNAF
LNMFETLVKA VGDLDAVMGF EMMNEPHRGY IELKSLHAFD YNTDLHLDYI PTAFESFQLG
AGYPTEVAKW TRSFPFPTTK TGSSVLNVEG RSAWRADGPT KGQCLWEMHG VWGWDVKKDM
AVVLRESYFV KHPMTGRKID WYTDFYYPFV QKWAERIQPS GKLVFVESIP NEEYRPRNMV
YAPHWYDLNA LFSKAFGDFS VNVQGLSRGM FLPKALYWGQ KGARDNYALQ IRNVVQAGYR
SLGELPVLIG ECGVPMDMNE GKAFETDDWR WQSRMMDAMI VGLERALVGF TLWNYNPLNS
DETGDTWNGE NFSWFSRRRA LPPFLLSYEQ ASPTLDNGGR ILSSVVRPYP AKTAGIPLKW
EYEVTTGRAV FEWITPKGVG LGGGNDDVSE GANVDNPPVD THVRITSYET EIFVPSGGEV
VVTELAKGDR WTYDENRQTL FVVTANNRPG TEHRLVIQLD PPRMEPGIGS WIVNDFWGDF
GSLILGVLCL TVALVAFVAM MVAGR
//
