ID   A0A0D7A9I5_9AGAR        Unreviewed;      1017 AA.
AC   A0A0D7A9I5;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=phosphoinositide 5-phosphatase {ECO:0000256|ARBA:ARBA00013044};
DE            EC=3.1.3.36 {ECO:0000256|ARBA:ARBA00013044};
GN   ORFNames=FISHEDRAFT_45168 {ECO:0000313|EMBL:KIY47483.1};
OS   Fistulina hepatica ATCC 64428.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Fistulinaceae; Fistulina.
OX   NCBI_TaxID=1128425 {ECO:0000313|EMBL:KIY47483.1, ECO:0000313|Proteomes:UP000054144};
RN   [1] {ECO:0000313|EMBL:KIY47483.1, ECO:0000313|Proteomes:UP000054144}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 64428 {ECO:0000313|EMBL:KIY47483.1,
RC   ECO:0000313|Proteomes:UP000054144};
RX   PubMed=25683379; DOI=10.1016/j.fgb.2015.02.002;
RA   Floudas D., Held B.W., Riley R., Nagy L.G., Koehler G., Ransdell A.S.,
RA   Younus H., Chow J., Chiniquy J., Lipzen A., Tritt A., Sun H., Haridas S.,
RA   LaButti K., Ohm R.A., Kues U., Blanchette R.A., Grigoriev I.V., Minto R.E.,
RA   Hibbett D.S.;
RT   "Evolution of novel wood decay mechanisms in Agaricales revealed by the
RT   genome sequences of Fistulina hepatica and Cylindrobasidium torrendii.";
RL   Fungal Genet. Biol. 76:78-92(2015).
CC   -!- SIMILARITY: Belongs to the synaptojanin family.
CC       {ECO:0000256|ARBA:ARBA00008943}.
CC   -!- SIMILARITY: In the central section; belongs to the inositol 1,4,5-
CC       trisphosphate 5-phosphatase family. {ECO:0000256|ARBA:ARBA00009678}.
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DR   EMBL; KN881933; KIY47483.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D7A9I5; -.
DR   OrthoDB; 996872at2759; -.
DR   Proteomes; UP000054144; Unassembled WGS sequence.
DR   GO; GO:0004439; F:phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity; IEA:UniProt.
DR   GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR   InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR   InterPro; IPR046985; IP5.
DR   InterPro; IPR000300; IPPc.
DR   InterPro; IPR002013; SAC_dom.
DR   PANTHER; PTHR11200; INOSITOL 5-PHOSPHATASE; 1.
DR   PANTHER; PTHR11200:SF257; PHOSPHOINOSITIDE 5-PHOSPHATASE; 1.
DR   Pfam; PF02383; Syja_N; 1.
DR   SMART; SM00128; IPPc; 1.
DR   SUPFAM; SSF56219; DNase I-like; 1.
DR   PROSITE; PS50275; SAC; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000054144}.
FT   DOMAIN          155..502
FT                   /note="SAC"
FT                   /evidence="ECO:0000259|PROSITE:PS50275"
FT   REGION          905..935
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          956..1017
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        956..981
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1003..1017
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1017 AA;  114115 MW;  6FEC5EBD1A4764DC CRC64;
     MYLYLGNGFR VLYLVTSPSE EKQGRPKRVL VFRAREDNPT QAIVEFLPKD EVDLSTAIRL
     TSRVIHGLLG LINIENEIFL AVVTSATEVG NTRPSAKYPE NAARLHEASF YSLNSSTWDE
     FAAAGSGDPL QNPDLDPTIL GSVTPPTFEH PCLPLIKILC SGSFYYATNA QWDLSSRLAV
     RLSRGEYDPA TFDGRFVWNE YIVRSLLDFR DRLEAFERDE FDRCHYIALT IQGYVGTATL
     ALPAPPTNGA PSIATLSLIS RLGWKRAGTR FNTRGVDDDG NCANFVETEV ILATDQHCVS
     YVQVRGSVPL FWEQQGLQTF GQRIQITRPH ASQPAFERHF RQLIEEYGGG VHAVNLLGSK
     ENEAILTSAY ARHIQTVGAS LGETVDITHF DFHNVVKMGG HEYLARELRR CETLVNYVDK
     FGFTMCDASN DEVVTKQSGV FRTNCLDCLD RTNFVQDIIS RLITEQYLFM TRREWLHAHA
     LWSHHRELWA ENGDALSRIY AGTGALNTSF TRTGKRTLAG VLSDATKSVS RAYINNFQDR
     SKQIAIDTFL GNLSDQRQVT IFDPIHDYVR AALEQRLAEY STTKHCTIFA GTWNVNGRAP
     SESLLPWLFP RDSIPDIFVL AFQEIVPLTA SQILQTDPEK RHVWETAIMK TLDQRPHKKC
     DYVLLRSEQL VGTALFVLVK AELTAVIRNV EAATRKTGLR GMSGNKGAVG VRLDYHDTSF
     CFLTAHLAAG HVNVFERNAD YRTIASGLHF QKGKTIDGHE NVVWAADTNY RIDLENDNVR
     IMADKDELDA LLGADQLRNA IDLGHAFVGY EEGPLLFRPT YRYDLGTQYY DTSEKMRIPA
     WTDRILYKGN QLDLSVYSRA ELMGSDHRPV FAIFRAAVRI IDAAKRTTLS KSLLDTVTST
     ASGEKLDDKL TSMMRSPDYP ELPPPSSDER AWWDTPEYPN GKLPVAELQA LSMSQRPNQT
     NPFDSPVESP LSSSPSSLDE ELYTDALTLH RPPSVVQATT PLPVQRRPPP PLPARSS
//