ID A0A0D7B3T5_9AGAR Unreviewed; 1054 AA.
AC A0A0D7B3T5;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Calcium permease {ECO:0008006|Google:ProtNLM};
GN ORFNames=CYLTODRAFT_379736 {ECO:0000313|EMBL:KIY65228.1};
OS Cylindrobasidium torrendii FP15055 ss-10.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae;
OC Cylindrobasidium.
OX NCBI_TaxID=1314674 {ECO:0000313|EMBL:KIY65228.1, ECO:0000313|Proteomes:UP000054007};
RN [1] {ECO:0000313|EMBL:KIY65228.1, ECO:0000313|Proteomes:UP000054007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FP15055 ss-10 {ECO:0000313|EMBL:KIY65228.1,
RC ECO:0000313|Proteomes:UP000054007};
RX PubMed=25683379; DOI=10.1016/j.fgb.2015.02.002;
RA Floudas D., Held B.W., Riley R., Nagy L.G., Koehler G., Ransdell A.S.,
RA Younus H., Chow J., Chiniquy J., Lipzen A., Tritt A., Sun H., Haridas S.,
RA LaButti K., Ohm R.A., Kues U., Blanchette R.A., Grigoriev I.V., Minto R.E.,
RA Hibbett D.S.;
RT "Evolution of novel wood decay mechanisms in Agaricales revealed by the
RT genome sequences of Fistulina hepatica and Cylindrobasidium torrendii.";
RL Fungal Genet. Biol. 76:78-92(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19)
CC family. {ECO:0000256|ARBA:ARBA00008170}.
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DR EMBL; KN880599; KIY65228.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D7B3T5; -.
DR STRING; 1314674.A0A0D7B3T5; -.
DR OrthoDB; 8346at2759; -.
DR Proteomes; UP000054007; Unassembled WGS sequence.
DR GO; GO:0005774; C:vacuolar membrane; IEA:UniProt.
DR GO; GO:0015369; F:calcium:proton antiporter activity; IEA:UniProt.
DR Gene3D; 1.20.1420.30; NCX, central ion-binding region; 2.
DR InterPro; IPR004713; CaH_exchang.
DR InterPro; IPR004837; NaCa_Exmemb.
DR InterPro; IPR044880; NCX_ion-bd_dom_sf.
DR InterPro; IPR005185; YccF.
DR PANTHER; PTHR31503:SF10; CATION_H+ EXCHANGER PROTEIN 1-RELATED; 1.
DR PANTHER; PTHR31503; VACUOLAR CALCIUM ION TRANSPORTER; 1.
DR Pfam; PF01699; Na_Ca_ex; 2.
DR Pfam; PF03733; YccF; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000054007};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 186..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 217..233
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..491
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 503..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 542..564
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 576..598
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 610..630
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 681..701
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 864..887
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 899..920
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 932..953
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 973..990
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 997..1015
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 184..234
FT /note="Inner membrane component"
FT /evidence="ECO:0000259|Pfam:PF03733"
FT DOMAIN 513..700
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT DOMAIN 862..1012
FT /note="Sodium/calcium exchanger membrane region"
FT /evidence="ECO:0000259|Pfam:PF01699"
FT REGION 1..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 244..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 407..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 741..776
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..80
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 91..105
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 750..770
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1054 AA; 115367 MW; 9A19C8C840911035 CRC64;
MSHHQGQSSG DLDEPASSTP TPSSRLHRSM SRSSQRSQTA DNHQSWSSPS SRPGPTPILL
RTGSSASMAR GPSRSFSVNS IPRHLHDDDV SERDEDEDDD EDEDGSEGTH RARSRIISDD
GEDDEDEDPI TVRERQSMIN VEHPFGLPIW KPALYKKSRS VTRHADEALH SVPSAQAERH
LLPGNILWLV VFGWWLALVT FFASAILYVV PQGGKRYSNL LFGLGWYIAW PFGKYVEGAQ
FEVEEEEEEE EEATHERQLS AESSHTVRDA ASTVRAGSHA QSSHVQTLSW NPVTIPGEHT
SLLQTVSEIR PSKSYGATVS PASDTSEDSI GVAKANNAAD LLGKICFWTF IVALIAPLML
IVCLICWGLV VTIPMAKLNW ALLKHLFTQP HSIRFCAAPP AVVVAEAADE EDPESPEDTA
SPTSRFSVKH PRISPGQVAP SGSSKVLLCI YRAVGWKYYK YTVGGVNILF INLLPVVFCV
IIDGLVLLPM VEHKLEHGQH VHPLLAIIAS QGLIFVMSLL SVIPLSYFIG MAVASISAQS
SIGMGAVINA TFGSIIEIIL YGMALSQSKG HLVEGSIIGS LLAGVLLMPG MSMVSSAIRR
KEQRFNAKSA GVTSMMLIMA LIGTLAPTLF YQTYGNFQLV CKGCPTAGPG TSSKPWICDQ
CYYKHPDPVD DPFYQATVKT FMYFCAVILV LSYLIGLWFS LRTHASQIWQ NPQQLLHQDA
TLPTHNRLSV YQRLVPPHVL RRKESRATNV GERSPTPHNT QRTATPSFPR RVSHASGAGI
SPVIDTVHRD VKNSGLQPLN LPEAMTADDF TRAVAVATVS ALRQHEAIPH SPAPHRVSGA
DGADVGGHGG HDAPSWSRTV SASVLLGCTL LYAIIAEILV DVVDVILQGS GIDEKFLGVT
LFALVPNTTE FMNAMSFALN GNIALSMEIG SAYALQVCLL QIPAMVAFSA WYAPEYMGEV
AKTFTLIFPR WDVIALILSM FLMTYTYIEA KSNYHRGSIL ILSYLVLLAG FYFAPSDKFD
DEVEMFGAGR GMQEFGVMNG LEYAKWWVLS WLPL
//
