ID A0A0D7B6A2_9AGAR Unreviewed; 3454 AA.
AC A0A0D7B6A2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Dynein heavy chain, cytoplasmic {ECO:0000256|ARBA:ARBA00022197};
DE AltName: Full=Dynein heavy chain, cytosolic {ECO:0000256|ARBA:ARBA00033439};
GN ORFNames=CYLTODRAFT_491828 {ECO:0000313|EMBL:KIY66037.1};
OS Cylindrobasidium torrendii FP15055 ss-10.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae;
OC Cylindrobasidium.
OX NCBI_TaxID=1314674 {ECO:0000313|EMBL:KIY66037.1, ECO:0000313|Proteomes:UP000054007};
RN [1] {ECO:0000313|EMBL:KIY66037.1, ECO:0000313|Proteomes:UP000054007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FP15055 ss-10 {ECO:0000313|EMBL:KIY66037.1,
RC ECO:0000313|Proteomes:UP000054007};
RX PubMed=25683379; DOI=10.1016/j.fgb.2015.02.002;
RA Floudas D., Held B.W., Riley R., Nagy L.G., Koehler G., Ransdell A.S.,
RA Younus H., Chow J., Chiniquy J., Lipzen A., Tritt A., Sun H., Haridas S.,
RA LaButti K., Ohm R.A., Kues U., Blanchette R.A., Grigoriev I.V., Minto R.E.,
RA Hibbett D.S.;
RT "Evolution of novel wood decay mechanisms in Agaricales revealed by the
RT genome sequences of Fistulina hepatica and Cylindrobasidium torrendii.";
RL Fungal Genet. Biol. 76:78-92(2015).
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DR EMBL; KN880568; KIY66037.1; -; Genomic_DNA.
DR STRING; 1314674.A0A0D7B6A2; -.
DR OrthoDB; 312195at2759; -.
DR Proteomes; UP000054007; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd00009; AAA; 2.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 2.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45703; DYNEIN HEAVY CHAIN; 1.
DR PANTHER; PTHR45703:SF34; DYNEIN HEAVY CHAIN, CYTOPLASMIC; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000054007}.
FT DOMAIN 738..888
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1415..1565
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 1757..1923
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT COILED 439..466
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 2238..2314
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 3454 AA; 392404 MW; 0609A65A9D97D1ED CRC64;
MEVFASGNSS TAAAVTFITF VQDLKKKTKT WGPMIDLCAS GEKTLERFRY QFPEDWLYSD
QLRGEWSAYN EILKRKNDSI QEQLAGLQVK INAEDHIAEQ KITDILAEWE QTRPVQGNMR
ADTAMNVINV FEGKLNRTQE HYDLVCRAKE ALDLELVRHT RLEPVFEELR DLKAVWTALS
GIWSQISELR DMSWATVQPR KLRQHIDGLL TSTKDMPTKM RQYAAFEYVQ DTLRGLLKSN
SVVSELKSDA LKDRHWKQLF KVLKVPTQIS LTLMTLGHVY DLDLKKNETL IKEVIIQAQG
EMALEEYIKQ VKEIWTNYTL ELVNYQNKCR LIRGWDDLFN KCSENLNSLT AMKLSPYYKV
FEEEASSWED KLNRIHVLFD VWIDVQRQWV YLEGIFSGSA DIKHLLPVES SRFQNINAEF
LTVMKKVYKS PFVIDVMNIQ GIQKSLERLA DLLNKIQKAL GEYLERERSS FPRFYFVGDE
DLLEIIGNSK DILRIMKHLK KMFAGISTIK LDDDLTQIQG MASREGEEVA FSEPINLKDF
PKINDWLARI EMMMRLSLAN LLVAAVDELQ TFYGTGEKLP QDRFMEWMEK YPAQLVTLAV
QVAWTASVES CLEAGSVPES PLETVRQALD LLADIVLQEL TPVTRRKCEH LITELVHQRD
VTRALIQQDV RDNKGFTWLY QMRFYLDRSV TNPLEKLSIQ TADASFPYGW EYLGVPDRLV
QTPLTDRVYL TLTQALDNQL GGAPFGPAGT GKTESVKALG VQLGRFVLVF CCDETFDFQA
MGRIFVGLCQ VGAWGCFDEF NRLEERILSA VSQQVQTIQQ GLASLVKNPN TEIELVGKNL
KLNKNIGIFI TTNPNYAGRS QLPPNLTKLF RPMAMTRPDR ELIAQVMLFS QGFRTAESLA
SKIVPFFNLC DEQLSPQPHY DFGLRALKAV LASAGILKRE RLSNAKAAAE GEDPAVGLSD
SISEQIIVIQ SVTETIVPKL VADDVPLLTN LLADVFPGVD YIPVDLDALK EQILKVCQER
RLVEGDLWIA KILQLYQIQK IQHGLMMVGP SGTGKTNAWQ VLLAALERLD GIEGVPYVID
PKAIHKDALY GTLDPTTREW NDGLFTHILR KIVDDVRGES NKRHWIIFDG DVDPEWVENL
NSVLDDNKLL TLPNGERLNL PPNVRIMFEV EHLKYATLAT VSRCGMIWFS EDVVEPSMVY
RNYLSTLSTV TLDADDEEAD PLSRRMEPLA ADAASTATLA IQKQVASILE QFFQEGDLVS
AALQFAETIE HIMDFTVTRA LNTLFSLLNK TVRNIIEYNN QHPDFHLPQD KVEAYVTKRL
LVSIIWAFSG DAKLDLRAEM GEFLRGQTGI DLPPLGPGSS LLDFDVQANT GEWVAWSTRV
PVIEIEAHSV TASDQVVPTM DTVRHEEVLY SWLSEHKPLM LCGPPGSGKT MTLFSALRKL
PDMEVAGLNF SSATTPELIL KTFDQYCEYR KTPNGVILAP VQIGRWLVVF CDEINLPAAD
KYGTQRVISF IRQLVECNGF WRSSDMAWVR LERIQFVGAC NPPTDPGRVP LTHRFLRHAP
LVMVDYPGEV SLKQIYGTYN RAALKAVPSL RPYAEPLTDA MVDFYLASQK RFTTDAQAHY
VYSPRELTRW VRGIYEAIKP LETLSAEGLV RVWAHEALRL FQDRLVSEEE RQWTDENIDG
VAMQHFPTMN RDEALMRPIL FSNWTSKDYI PVDRDTLREY TKARLKVFYE EELDVPLVLF
NDVLDHVLRI DRVFRQIQGH LLLIGVSGSG KTTLSRFVAW MNGLSIFQIK VSNKYTGEDF
DDDLRTVLRR SGCKGEKICF IMDESNVLDS GFLERMNTLL ANAEVPGLFE GDEHAALMTA
CKEGSQRDGL MLDSHEELYR WFTQQVARNL HVVFTMNPPE NGLASRAATS PALFNRCVLD
WFGDWSDQAF YQVGMEFTNN LDLDLSSYVP PANFPIAYRG LSMPPIHRTA VVNGLVYVHE
SLHQINQRLS RRQGRYNYVT PRHYLDFINH YVRLYTEKRD ELEEQQRHLH VGLDKLKDTV
TEVEKLRASL AVKRSQLSAK DAEANEKLKR MVADQQEAEQ KKSASIELQK ELAIQDKHIE
QRKAVATADL ANAEPAVLEA QSAVSNIRRQ HLQEVRTMAN PPEAVKLAME SVCTVLGHKI
DSWRTVQGII RREEFIQSII NFDTQSQMTK HLRETMKKDF LSRPSYNFET VQRASRACGP
LVKWVIAQVQ FSDILDRVEP LRNEVQNLET QAETTKKQAT AIIDMIAELE SKIALYKDEY
ALLISETQAI KAEMQRVESK VDRSMKLLDS LSSERVRWES GSRAFDAEMS TIVGDVLLSA
AFLAYGGFFD QHYREVMWQD WASHLTDAGI TFKTELSLTE YLSTADDRLS WQSKSLPADN
LTTENAIMLK RFNRYPLIID PTGQATTFLL NEYKERKITV TSFLDESFLK VLESALRFGN
ALLIQDVEHL DPILNAVLNK EIRRTGGRVL IRLGSQDIDF SPSFTMFLST RDPSVEFSPD
ICSRVTFVNF TMTRSSLQSQ SLDQVLKVER PDTERKRTDL MKLQGEFRVR LRTLEKLLLQ
ALNESSGNIL DDDKVIESLE KLKKDAAEIT SKVEETDVVM REVEEVTAEY LPLAQACSAV
FFILEQLNLV NHFYQFSLQF FLDIFNYILY QNPRLKSVSD YHARREILVN DLFLIVYKRT
SRALLYRDHV MLAVLLAQVK MRGVEDFSEE LEFLLESSDS VVASVTGSTV PEIGFLSTDQ
NLRLDNYSKQ SLFKPVHGHI VDHEEDWQVF LKSSSPEDAV PMPWEPSTPA VEAIRAMLVV
KCLRPDRLLE ATARFVRVVF NTDLALESAY DLGAIVTDEI PPSTPIALVS VSGYDASFRV
ENLIKNSGTR SSSVAMGSQE GFAQADQAIA AAARQGTWVL LKNVHLAPSW LGQLEKKVQT
LNPARSFRLF LTMETNPSIP VNILRQSRLI MNEPPPGVKA NLLDSLKSIP SWRLNQGPAE
KSRLYFLLAW FHAVVQERLR YVPLGWSKTY DFNDSDQNSA FTTIDTWLNS VAKGRANIDP
ITIPWDAVRT LVKQSVYGGR VDSDFDQRIL DSFVDSLFRP QAYNVDFELV PSLTGEGVLT
APDGTKIDQF LSWVQNLPDR QPPAWLSLPP SAERVIAIAQ GNELLGKLRK MRLLADDDDE
ATPTASSSSS SQQPAWMRAL YDRCKEWLEL LPEKFQTLPP SNDNQDPLYR LFAREGEIGR
RLLGQVRRDL ADILKVCLGE LKQTNHLRSL MSELTKGTIP NHWRRYKVPK SMSVSGWVID
FARRLNQLDR VAGLNNLNDV EVWLGGLFFP EAYVTATRQA VAHRKRWSLE TLSLQLDIEK
VNDPEAFIID GLSIEGASWQ SDKLVLNEGE VVRLGASQIR WVQTDGTSSP KGLSNLPIYL
NGDRSDVLFT VDLPFDSSAG LLVAMRAVCL TANT
//
