ID   A0A0D7BKH7_9AGAR        Unreviewed;       843 AA.
AC   A0A0D7BKH7;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   03-MAY-2023, entry version 22.
DE   RecName: Full=Probable vacuolar protein sorting-associated protein 16 homolog {ECO:0000256|PIRNR:PIRNR007949};
GN   ORFNames=CYLTODRAFT_347307 {ECO:0000313|EMBL:KIY70700.1};
OS   Cylindrobasidium torrendii FP15055 ss-10.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae;
OC   Cylindrobasidium.
OX   NCBI_TaxID=1314674 {ECO:0000313|EMBL:KIY70700.1, ECO:0000313|Proteomes:UP000054007};
RN   [1] {ECO:0000313|EMBL:KIY70700.1, ECO:0000313|Proteomes:UP000054007}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=FP15055 ss-10 {ECO:0000313|EMBL:KIY70700.1,
RC   ECO:0000313|Proteomes:UP000054007};
RX   PubMed=25683379; DOI=10.1016/j.fgb.2015.02.002;
RA   Floudas D., Held B.W., Riley R., Nagy L.G., Koehler G., Ransdell A.S.,
RA   Younus H., Chow J., Chiniquy J., Lipzen A., Tritt A., Sun H., Haridas S.,
RA   LaButti K., Ohm R.A., Kues U., Blanchette R.A., Grigoriev I.V., Minto R.E.,
RA   Hibbett D.S.;
RT   "Evolution of novel wood decay mechanisms in Agaricales revealed by the
RT   genome sequences of Fistulina hepatica and Cylindrobasidium torrendii.";
RL   Fungal Genet. Biol. 76:78-92(2015).
CC   -!- FUNCTION: Essential for vacuolar protein sorting. Required for vacuole
CC       biogenesis, stability and to maintain vacuole morphology.
CC       {ECO:0000256|PIRNR:PIRNR007949}.
CC   -!- SIMILARITY: Belongs to the VPS16 family.
CC       {ECO:0000256|ARBA:ARBA00009250, ECO:0000256|PIRNR:PIRNR007949}.
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DR   EMBL; KN880464; KIY70700.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D7BKH7; -.
DR   STRING; 1314674.A0A0D7BKH7; -.
DR   OrthoDB; 1110811at2759; -.
DR   Proteomes; UP000054007; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0012505; C:endomembrane system; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0032991; C:protein-containing complex; IEA:UniProt.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR   GO; GO:0007033; P:vacuole organization; IEA:InterPro.
DR   Gene3D; 1.10.150.780; Vps16, C-terminal region; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR   InterPro; IPR016534; VPS16.
DR   InterPro; IPR006925; Vps16_C.
DR   InterPro; IPR038132; Vps16_C_sf.
DR   InterPro; IPR006926; Vps16_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR12811; VACUOLAR PROTEIN SORTING VPS16; 1.
DR   PANTHER; PTHR12811:SF0; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 16 HOMOLOG; 1.
DR   Pfam; PF04840; Vps16_C; 1.
DR   Pfam; PF04841; Vps16_N; 1.
DR   PIRSF; PIRSF007949; VPS16; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   3: Inferred from homology;
KW   Protein transport {ECO:0000256|PIRNR:PIRNR007949};
KW   Reference proteome {ECO:0000313|Proteomes:UP000054007};
KW   Transport {ECO:0000256|PIRNR:PIRNR007949}.
FT   DOMAIN          5..415
FT                   /note="Vps16 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04841"
FT   DOMAIN          520..827
FT                   /note="Vps16 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04840"
SQ   SEQUENCE   843 AA;  94016 MW;  5301D89C6B54027C CRC64;
     MPDHPTASWQ AMQDGNVFYR RQQLYSVPGK FPEFGDHISA GCRYGGPIAM TRDTTKLIAL
     GRPTPTVSRA QIQVWSPSAV GLLLFSWDQG KIVRFGWTGD ERLVVINEEG TYRIYDLQGD
     YQQYSLGSEA SESGVIDARI HDTGLVALTG GLSLLEVKGW EGARTMTLAS AAGLNQPPHS
     WAIIPPDLNI SRHVQVLLSV DSTILLVDTL ECLDQRISQG PFTHISPSPN GKTLALLTFT
     GTLLVISSDF QRHITEFDTS SIQADGTVRQ VEWCGNDAIL LTWDDLVVLV GPFADTLQYI
     YGGPVFAVSE PDGVRIMGPD TCDLIQKVPA SVLSIFRPGS TSPASILYDA WQSFTDRSPK
     ADDAIRSIRP DLASAVDQCI DAAGREWEPY WQRSLLNAAK FGRGFLDLYN PNDFVNMGRT
     LKVLNAVRFY EIGVPMTYDQ YQYASPSSLV SRLTARNMHL LALRISSYLG MKPHAVLRHW
     ASAKILKSKP TATLDGELNG DEEVCRAIVD KFKELGGSDV SYAEIAKRAW EVGRTGLATK
     LLDYEPNASD QVPLLLSMKE DRLALEKAVD SGDTDLVYTV LLQLHRRLAL GDFFRLLEDG
     GEKLVPASRL LQVYAREQNR SMLRDFYYSD DRRVESAVLA LDESTTMMDP AAKLTSVKSA
     QKFFSEDKDR GFEAKMMDEY GRLLALQQQL EKDADGRVVL YGLSVTETIR ACLTNGLSKK
     ADKVKSDFKV PDKRFWHVKL NALVEQQDFD GLDAFAKSKR SPIGYEPFVR RLLEHKHSKE
     AIAYVARCDS PKRADLYAEC GDWRAAGKEC KERGDRGKLD ELRQRCKDSL ALRDLDQIAS
     SWK
//