ID A0A0D7BN40_9AGAR Unreviewed; 873 AA.
AC A0A0D7BN40;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE SubName: Full=Ras GEF {ECO:0000313|EMBL:KIY71610.1};
GN ORFNames=CYLTODRAFT_345546 {ECO:0000313|EMBL:KIY71610.1};
OS Cylindrobasidium torrendii FP15055 ss-10.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae;
OC Cylindrobasidium.
OX NCBI_TaxID=1314674 {ECO:0000313|EMBL:KIY71610.1, ECO:0000313|Proteomes:UP000054007};
RN [1] {ECO:0000313|EMBL:KIY71610.1, ECO:0000313|Proteomes:UP000054007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FP15055 ss-10 {ECO:0000313|EMBL:KIY71610.1,
RC ECO:0000313|Proteomes:UP000054007};
RX PubMed=25683379; DOI=10.1016/j.fgb.2015.02.002;
RA Floudas D., Held B.W., Riley R., Nagy L.G., Koehler G., Ransdell A.S.,
RA Younus H., Chow J., Chiniquy J., Lipzen A., Tritt A., Sun H., Haridas S.,
RA LaButti K., Ohm R.A., Kues U., Blanchette R.A., Grigoriev I.V., Minto R.E.,
RA Hibbett D.S.;
RT "Evolution of novel wood decay mechanisms in Agaricales revealed by the
RT genome sequences of Fistulina hepatica and Cylindrobasidium torrendii.";
RL Fungal Genet. Biol. 76:78-92(2015).
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DR EMBL; KN880452; KIY71610.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D7BN40; -.
DR STRING; 1314674.A0A0D7BN40; -.
DR OrthoDB; 4819765at2759; -.
DR Proteomes; UP000054007; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00882; Ras_like_GTPase; 1.
DR CDD; cd06224; REM; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF348; GUANYL-NUCLEOTIDE EXCHANGE FACTOR RASGEF, PUTATIVE (AFU_ORTHOLOGUE AFUA_1G04700)-RELATED; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000054007}.
FT DOMAIN 372..497
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 605..843
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 1..57
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 273..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 517..559
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 836..860
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 23..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 273..337
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 338..372
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..857
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 873 AA; 97519 MW; BB223A9E03140A85 CRC64;
MSSVTTSTAS LHDTPPPPIV PRMQSSSSLQ SMARRTAPPP TARSRSGSLG VLPPSSSRRV
TAMTIQQLDH PLTMTLVVVG TPGCGKSTVI RKGLKGFQLS EPTPSLPGTH ALRYTKRIGR
LPRTDEPQDC PLIIIEVDIP TAISDTLSAM DLLPEPTRID GVLICYSASD EPSFRPVEAL
LRGYRQLQLP TVVVACKSDL PKAVDPLTSV EILLQYDVGL IEVNNTSDAG TGKMRRSFDW
LLKAVLRDRL RNQLDDYRNP ASPNLVANHP AWESASRTST PVGPLPTPSS TSTSTRHGRT
PSRVPSADTL SSGAEHTLST HSIPESQVPT LPLDQETPAS TEHDHSDHPP TQSEEALGHI
SSDERKPPRR QDARPAQWAT LDELLDKLLF LAVSGDDPTY ITHFLLTYRR FASPRSVLLA
MQKRMRQLDS PSGDPMFACY AQMRICHLLE VWIRDYPYDF AVRGTAGALS ALIKSIISKT
YLLHYGSDFL PFLEMLPSLV DKDADWAHKA DEIEVESDDS YSLLEDDDDK SPDTSPKAKQ
SQTTSSPVKD KLPAAQRERK GSLPLTAKAL LPSLENTLAF EQAPETPKQQ LKELQRLAAE
VNLTDPEELA KEITRLEAKL FLDIEPRHWL HYTFVSGKKD PEVNSIARFN NVSNHLADWV
VSLILCHDKP RMRAKQIEKF VEIAQKLRSL NNYSALRAFV AGINNATYPG DPTLDQFKSR
CPEQAKNLQS WDVLLQHIRA HRAYRLALRN TKGACIPALE VHISDLIRSH EANPDMSTND
PSRIHWGKFN MIGRFITSTT QCQAQCRSTQ DYNFSERPDL RNMLLVNCLM DNEMQKSRIT
PPDGEYDDYR PARPQRDPSA PRDVAILRRL LFW
//
