ID A0A0D7BTD8_9AGAR Unreviewed; 360 AA.
AC A0A0D7BTD8;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=(2E,6E)-farnesyl diphosphate synthase {ECO:0000256|ARBA:ARBA00032873};
DE EC=2.5.1.1 {ECO:0000256|ARBA:ARBA00012833};
DE EC=2.5.1.10 {ECO:0000256|ARBA:ARBA00012439};
DE AltName: Full=Dimethylallyltranstransferase {ECO:0000256|ARBA:ARBA00032448};
DE AltName: Full=Farnesyl diphosphate synthase {ECO:0000256|ARBA:ARBA00032424};
DE AltName: Full=Geranyltranstransferase {ECO:0000256|ARBA:ARBA00032380};
GN ORFNames=CYLTODRAFT_388168 {ECO:0000313|EMBL:KIY72871.1};
OS Cylindrobasidium torrendii FP15055 ss-10.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Marasmiineae; Physalacriaceae;
OC Cylindrobasidium.
OX NCBI_TaxID=1314674 {ECO:0000313|EMBL:KIY72871.1, ECO:0000313|Proteomes:UP000054007};
RN [1] {ECO:0000313|EMBL:KIY72871.1, ECO:0000313|Proteomes:UP000054007}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FP15055 ss-10 {ECO:0000313|EMBL:KIY72871.1,
RC ECO:0000313|Proteomes:UP000054007};
RX PubMed=25683379; DOI=10.1016/j.fgb.2015.02.002;
RA Floudas D., Held B.W., Riley R., Nagy L.G., Koehler G., Ransdell A.S.,
RA Younus H., Chow J., Chiniquy J., Lipzen A., Tritt A., Sun H., Haridas S.,
RA LaButti K., Ohm R.A., Kues U., Blanchette R.A., Grigoriev I.V., Minto R.E.,
RA Hibbett D.S.;
RT "Evolution of novel wood decay mechanisms in Agaricales revealed by the
RT genome sequences of Fistulina hepatica and Cylindrobasidium torrendii.";
RL Fungal Genet. Biol. 76:78-92(2015).
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the FPP/GGPP synthase family.
CC {ECO:0000256|RuleBase:RU004466}.
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DR EMBL; KN880440; KIY72871.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D7BTD8; -.
DR STRING; 1314674.A0A0D7BTD8; -.
DR OrthoDB; 509027at2759; -.
DR Proteomes; UP000054007; Unassembled WGS sequence.
DR GO; GO:0004161; F:dimethylallyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0004337; F:geranyltranstransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0008299; P:isoprenoid biosynthetic process; IEA:InterPro.
DR CDD; cd00685; Trans_IPPS_HT; 1.
DR Gene3D; 1.10.600.10; Farnesyl Diphosphate Synthase; 1.
DR InterPro; IPR039702; FPS1-like.
DR InterPro; IPR008949; Isoprenoid_synthase_dom_sf.
DR InterPro; IPR000092; Polyprenyl_synt.
DR InterPro; IPR033749; Polyprenyl_synt_CS.
DR PANTHER; PTHR11525:SF0; FARNESYL PYROPHOSPHATE SYNTHASE; 1.
DR PANTHER; PTHR11525; FARNESYL-PYROPHOSPHATE SYNTHETASE; 1.
DR Pfam; PF00348; polyprenyl_synt; 1.
DR SFLD; SFLDS00005; Isoprenoid_Synthase_Type_I; 1.
DR SUPFAM; SSF48576; Terpenoid synthases; 1.
DR PROSITE; PS00723; POLYPRENYL_SYNTHASE_1; 1.
DR PROSITE; PS00444; POLYPRENYL_SYNTHASE_2; 1.
PE 3: Inferred from homology;
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Reference proteome {ECO:0000313|Proteomes:UP000054007};
KW Transferase {ECO:0000256|RuleBase:RU004466}.
SQ SEQUENCE 360 AA; 41182 MW; 74E85134CC27B49D CRC64;
MSSTDKAVRR AKFEAVWKVV KQELVDHIKE QGMPDDVVDW FERNLEYNTP GGKLNRGMSV
VDTAEILKGR TLTDDEYFKA AVLGWGVELL QAFFLVSDDM MDSSITRRGQ PCYYRVPRVG
SIAINDSFML EAAIYFLLKK HFRSESYYVD LIELFMETTL QTEIGQLIDL TTAPEDSVDL
NKFSLEKHRL IVTYKTAYYS FYLPVALAYW LCGIPAEYTL KGKTVKPFEL AKDVLIPLGE
YFQVQDDFLD YSGTPEQIGK IGTDILDNKC SWCVNTALAR ATPEQRKILD ENYGRKDKEC
EARVKALYAE LDIAGIYAEY EENVYKKLTG IISDVPEGGE GTVKREVFTS FLSKIYKRQK
//
