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Database: UniProt
Entry: A0A0D7CEX6_9ACTN
LinkDB: A0A0D7CEX6_9ACTN
Original site: A0A0D7CEX6_9ACTN 
ID   A0A0D7CEX6_9ACTN        Unreviewed;       235 AA.
AC   A0A0D7CEX6;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   03-JUL-2019, entry version 22.
DE   RecName: Full=Urease {ECO:0000256|SAAS:SAAS00108089};
DE            EC=3.5.1.5 {ECO:0000256|SAAS:SAAS00108089};
GN   ORFNames=SNA_33010 {ECO:0000313|EMBL:KIZ13952.1};
OS   Streptomyces natalensis ATCC 27448.
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1240678 {ECO:0000313|EMBL:KIZ13952.1, ECO:0000313|Proteomes:UP000032458};
RN   [1] {ECO:0000313|EMBL:KIZ13952.1, ECO:0000313|Proteomes:UP000032458}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27448 {ECO:0000313|EMBL:KIZ13952.1,
RC   ECO:0000313|Proteomes:UP000032458};
RA   Mendes M.V., Beites T., Pires S., Santos C.L., Moradas-Ferreira P.;
RT   "Draft genome sequence of Streptomyces natalensis ATCC 27448, producer
RT   of the antifungal pimaricin.";
RL   Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H(+) + H2O + urea = CO2 + 2 NH4(+);
CC         Xref=Rhea:RHEA:20557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16199, ChEBI:CHEBI:16526, ChEBI:CHEBI:28938;
CC         EC=3.5.1.5; Evidence={ECO:0000256|SAAS:SAAS01115730};
CC   -!- PATHWAY: Nitrogen metabolism; urea degradation; CO(2) and NH(3)
CC       from urea (urease route): step 1/1.
CC       {ECO:0000256|SAAS:SAAS00108095}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:KIZ13952.1}.
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DR   EMBL; JRKI01000061; KIZ13952.1; -; Genomic_DNA.
DR   RefSeq; WP_044367899.1; NZ_JRKI01000061.1.
DR   EnsemblBacteria; KIZ13952; KIZ13952; SNA_33010.
DR   PATRIC; fig|1240678.4.peg.7046; -.
DR   OrthoDB; 1755809at2; -.
DR   BioCyc; GCF_000935125:G1EKM-6486-MONOMER; -.
DR   UniPathway; UPA00258; UER00370.
DR   Proteomes; UP000032458; Unassembled WGS sequence.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   GO; GO:0009039; F:urease activity; IEA:UniProtKB-EC.
DR   GO; GO:0043419; P:urea catabolic process; IEA:UniProtKB-UniPathway.
DR   CDD; cd00407; Urease_beta; 1.
DR   CDD; cd00390; Urease_gamma; 1.
DR   Gene3D; 2.10.150.10; -; 1.
DR   Gene3D; 3.30.280.10; -; 1.
DR   InterPro; IPR002019; Urease_beta.
DR   InterPro; IPR036461; Urease_betasu_sf.
DR   InterPro; IPR002026; Urease_gamma/gamma-beta_su.
DR   InterPro; IPR036463; Urease_gamma_sf.
DR   Pfam; PF00699; Urease_beta; 1.
DR   Pfam; PF00547; Urease_gamma; 1.
DR   SUPFAM; SSF51278; SSF51278; 1.
DR   SUPFAM; SSF54111; SSF54111; 1.
DR   TIGRFAMs; TIGR00193; urease_gam; 1.
PE   4: Predicted;
KW   Complete proteome {ECO:0000313|Proteomes:UP000032458};
KW   Hydrolase {ECO:0000256|SAAS:SAAS00108092};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032458}.
SQ   SEQUENCE   235 AA;  24133 MW;  AB39665201345E22 CRC64;
     MRLTPTERDR LLLFNAAQLA RSRRSRGLRL NVPEATAVIA DTVCEAARDG RRLAQAIEAG
     RNALGPDDVL PGVAEVIGDV MVEAVFDDGS RLAVVSDPIG TLTEPGDAGG AGPAPGAVLP
     GPADPEPVPA VTVTVHNTAS VPISVTSHFH FFEANPRLDF DRAAAYGMRL CVPAGSSERF
     DAGGTHEVGL VPIGGARIAI GFAGLVDGPL DAPGAKTEAL RRAAACGYLG AEEQA
//
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