ID A0A0D7CS28_9ACTN Unreviewed; 346 AA.
AC A0A0D7CS28;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:KIZ18846.1};
GN ORFNames=SNA_06200 {ECO:0000313|EMBL:KIZ18846.1};
OS Streptomyces natalensis ATCC 27448.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1240678 {ECO:0000313|EMBL:KIZ18846.1, ECO:0000313|Proteomes:UP000032458};
RN [1] {ECO:0000313|EMBL:KIZ18846.1, ECO:0000313|Proteomes:UP000032458}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27448 {ECO:0000313|EMBL:KIZ18846.1,
RC ECO:0000313|Proteomes:UP000032458};
RA Mendes M.V., Beites T., Pires S., Santos C.L., Moradas-Ferreira P.;
RT "Draft genome sequence of Streptomyces natalensis ATCC 27448, producer of
RT the antifungal pimaricin.";
RL Submitted (SEP-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KIZ18846.1}.
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DR EMBL; JRKI01000008; KIZ18846.1; -; Genomic_DNA.
DR RefSeq; WP_030067506.1; NZ_JRKI01000008.1.
DR AlphaFoldDB; A0A0D7CS28; -.
DR PATRIC; fig|1240678.4.peg.1302; -.
DR Proteomes; UP000032458; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF152; HTH-TYPE TRANSCRIPTIONAL REGULATOR EBGR-RELATED; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 10..64
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 323..346
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 346 AA; 36817 MW; 62A971C17F371DBF CRC64;
MERSKGPHAP TIRGVAERAG VSKSLVSLVL QGSPRVSDAK RQAVLEAIEE LGYRPNAAAR
SLVARRTHTV GVLLDDLRNP WFVELLDGLN SVLCAHGLRM LMADSRLGRR TGEDVARTFL
ELRVDGVVAV GTLPDADTAA LAELAERLPT VVAGSHDPRL PGVDTVANDD ERGARLATEH
LIGLGHRRIA HIAGPGGVGE LRRRGYETTM REHGLGGELT VEPGDGTEEG GYRAAVRMLG
GRPAAAPERP TAVFAFNDFS AVGALSAARE LGLEVPRDLS LVGCDNTYLA RIRHLWLTTV
DNASHDVGRR AAQRLLDRME HPARPAGHGL AAPSLEVRGS TAPPPG
//
