ID A0A0D8CX59_9GAMM Unreviewed; 303 AA.
AC A0A0D8CX59;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=6-carboxy-5,6,7,8-tetrahydropterin synthase {ECO:0000256|ARBA:ARBA00018141};
DE EC=4.1.2.50 {ECO:0000256|ARBA:ARBA00012982};
DE AltName: Full=Queuosine biosynthesis protein QueD {ECO:0000256|ARBA:ARBA00031449};
GN ORFNames=SG35_12580 {ECO:0000313|EMBL:KJE41181.1};
OS Thalassomonas actiniarum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Colwelliaceae; Thalassomonas.
OX NCBI_TaxID=485447 {ECO:0000313|EMBL:KJE41181.1};
RN [1] {ECO:0000313|EMBL:KJE41181.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A5K-106 {ECO:0000313|EMBL:KJE41181.1};
RA Olonade I., van Zyl L.J., Tuffin M.I.;
RT "Genome sequence of Japanese sea anemone isolate Thalassomonas
RT actiniarum.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=7,8-dihydroneopterin 3'-triphosphate + H2O = 6-
CC carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) +
CC triphosphate; Xref=Rhea:RHEA:27966, ChEBI:CHEBI:15343,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:18036,
CC ChEBI:CHEBI:58462, ChEBI:CHEBI:61032; EC=4.1.2.50;
CC Evidence={ECO:0000256|ARBA:ARBA00001293};
CC -!- PATHWAY: Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.
CC {ECO:0000256|ARBA:ARBA00005061}.
CC -!- SIMILARITY: Belongs to the PTPS family. QueD subfamily.
CC {ECO:0000256|ARBA:ARBA00008900}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJE41181.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JYNI01000021; KJE41181.1; -; Genomic_DNA.
DR RefSeq; WP_044832775.1; NZ_CP059735.1.
DR AlphaFoldDB; A0A0D8CX59; -.
DR STRING; 485447.SG35_12580; -.
DR PATRIC; fig|485447.4.peg.2060; -.
DR OrthoDB; 5820615at2; -.
DR UniPathway; UPA00391; -.
DR GO; GO:0070497; F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.30.479.10; 6-pyruvoyl tetrahydropterin synthase/QueD; 2.
DR InterPro; IPR007115; 6-PTP_synth/QueD.
DR InterPro; IPR038418; 6-PTP_synth/QueD_sf.
DR Pfam; PF01242; PTPS; 1.
DR SUPFAM; SSF55620; Tetrahydrobiopterin biosynthesis enzymes-like; 2.
PE 3: Inferred from homology;
SQ SEQUENCE 303 AA; 34212 MW; 3987F4F2F6CCF7A5 CRC64;
MQLFVNDLTV IDFSYLCKHR GIVGESWIVD VLLDGDLNEQ SMVLDFAIVK KQIKAIIDDA
VDHKLLLPNK ESRLRVTNSV DNDQHEYVDF DSDVGSYYLQ SPKCAFAKID SEAVTIAAVT
AHLQTIIKQQ LPGNIQGLTL NLRPEKIDGF YYHYTHGLKK HDGNCQRIAH GHRSKIQLYK
NDMRSISLEK NWCQRWQDIY LASEEDRSSF EQIQLSPQAK AALDKETSAQ DEKAPGHQYF
AYHAPQGRFD IAVPSGILEV VDCDSTVELL ADYIARQLKK NSPQDNFKVV AFEGVAKGAI
ANV
//
