ID A0A0D8CX67_9GAMM Unreviewed; 1047 AA.
AC A0A0D8CX67;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Cation transporter {ECO:0000313|EMBL:KJE41186.1};
GN ORFNames=SG35_12630 {ECO:0000313|EMBL:KJE41186.1};
OS Thalassomonas actiniarum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Colwelliaceae; Thalassomonas.
OX NCBI_TaxID=485447 {ECO:0000313|EMBL:KJE41186.1};
RN [1] {ECO:0000313|EMBL:KJE41186.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A5K-106 {ECO:0000313|EMBL:KJE41186.1};
RA Olonade I., van Zyl L.J., Tuffin M.I.;
RT "Genome sequence of Japanese sea anemone isolate Thalassomonas
RT actiniarum.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. {ECO:0000256|ARBA:ARBA00010942}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJE41186.1}.
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DR EMBL; JYNI01000021; KJE41186.1; -; Genomic_DNA.
DR RefSeq; WP_044832780.1; NZ_CP059735.1.
DR AlphaFoldDB; A0A0D8CX67; -.
DR STRING; 485447.SG35_12630; -.
DR PATRIC; fig|485447.4.peg.2072; -.
DR OrthoDB; 9758757at2; -.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR027463; AcrB_DN_DC_subdom.
DR InterPro; IPR001036; Acrflvin-R.
DR InterPro; IPR004763; CusA-like.
DR InterPro; IPR003124; WH2_dom.
DR NCBIfam; TIGR00914; 2A0601; 1.
DR PANTHER; PTHR32063; -; 1.
DR PANTHER; PTHR32063:SF24; CATION EFFLUX SYSTEM (ACRB_ACRD_ACRF FAMILY); 1.
DR Pfam; PF00873; ACR_tran; 1.
DR PRINTS; PR00702; ACRIFLAVINRP.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS51082; WH2; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 347..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 372..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..418
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 439..463
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 483..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..554
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 882..901
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 908..927
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 933..958
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 978..999
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1011..1034
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 964..983
FT /note="WH2"
FT /evidence="ECO:0000259|PROSITE:PS51082"
SQ SEQUENCE 1047 AA; 112929 MW; 4811C9A55D62684C CRC64;
MIESLLRLSI ARRWLMISLA LMLTALGYWS YQKLPIDAVP DVTNVQVQIN TRAPGYSPLE
TEQRITYPVE TALTGIANLA YTRSLSRYGL SQVTVVFEEG TDLYFARSLI NERLNAIKGK
LPADLTPQMG PVSTGLGEIF MYTIEAGAEA VQADGRPYDA TALREIQDWI IKPQLALVPG
VTEINTIGGF DKEYHITPSP RKMLAFGISF EDITKALKSN NSNRGAGYIE GNGQQLTVRS
PGQLKTISDI EQVVVKNIRQ VPVKISDVAE VAIGKALRTG AATRDGRETV LGSAMMLTGE
NSRAVSLAVA AKLEQVKASL PEGIKVQAVY DRTDLVDKAV YTVQKNLLEG ALLVIAVLFL
LLGNVRAALI TAAVIPLAML ATITGMVRAG ISANLMSLGA LDFGLIVDGA VIIVENATRR
LAQAQHMGGK LGRKERLHVV FSATNEVIRP SLFGVIIITL VYIPLFSLTG VEGKMFHPMA
ATVVMALLSA LVLSLTLVPA AVALFMTGKI SEKESRVIIA AKLLYQPLLM AAMKLRYLVL
TAAVAFVAFS IYLATTLGSE FIPKLNEEDI LLQAIRIPGT SLEQAVEMQK ALEDGIKHFP
QVKNVFSKIG TPQVANDPMP PNIADTFIML KPRQMWPDPE MSYQALAAEI VEAVEGQPGN
NFELTQPIEM RFNELISGVR ADLGIKVIGD DLEQLLTSAN AIREVIEKID GASDIQVEQV
TGLPMLSIVP KRQQLARYGL NVSRLQDLVA TAIGGEGAGV IFEGDRRFKL VVRLPEALRR
DVLRLKDLPV PLPGANPLAG SMAGYVPLSE VAEIEIAPAP NQISRENGKR RIVVTANVRG
RDLGSFVAEA KSRIQQEVKI PAGYWLAYGG SFEQLQSASN RLSILVPLTL VLILGLLVMA
FASIKDALII FTGVPFALTG GVISLWLRDM PLSISAGVGF IALSGVAVLN GLVMLAFIRD
LCKERSDLLS AIIDGAMIRL RPVLMTALVA GLGFVPMALN IGTGAEVQRP LATVVIGGII
SSTLLTLLVL PVLYRIAHER SFNKANA
//
