ID A0A0D8D187_9GAMM Unreviewed; 718 AA.
AC A0A0D8D187;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=Peptidase {ECO:0008006|Google:ProtNLM};
GN ORFNames=SG35_10315 {ECO:0000313|EMBL:KJE41647.1};
OS Thalassomonas actiniarum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC Colwelliaceae; Thalassomonas.
OX NCBI_TaxID=485447 {ECO:0000313|EMBL:KJE41647.1};
RN [1] {ECO:0000313|EMBL:KJE41647.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=A5K-106 {ECO:0000313|EMBL:KJE41647.1};
RA Olonade I., van Zyl L.J., Tuffin M.I.;
RT "Genome sequence of Japanese sea anemone isolate Thalassomonas
RT actiniarum.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the peptidase M4 family.
CC {ECO:0000256|ARBA:ARBA00009388}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJE41647.1}.
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DR EMBL; JYNI01000018; KJE41647.1; -; Genomic_DNA.
DR RefSeq; WP_044832346.1; NZ_CP059736.1.
DR AlphaFoldDB; A0A0D8D187; -.
DR STRING; 485447.SG35_10315; -.
DR MEROPS; M04.003; -.
DR PATRIC; fig|485447.4.peg.1539; -.
DR OrthoDB; 5378341at2; -.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd09597; M4_TLP; 1.
DR Gene3D; 2.60.120.380; -; 2.
DR Gene3D; 3.10.170.10; -; 1.
DR Gene3D; 3.10.450.40; -; 1.
DR Gene3D; 3.10.450.490; -; 1.
DR Gene3D; 1.10.390.10; Neutral Protease Domain 2; 1.
DR InterPro; IPR011096; FTP_domain.
DR InterPro; IPR007280; Peptidase_C_arc/bac.
DR InterPro; IPR023612; Peptidase_M4.
DR InterPro; IPR027268; Peptidase_M4/M1_CTD_sf.
DR InterPro; IPR001570; Peptidase_M4_C_domain.
DR InterPro; IPR013856; Peptidase_M4_domain.
DR PANTHER; PTHR33794; BACILLOLYSIN; 1.
DR PANTHER; PTHR33794:SF1; BACILLOLYSIN; 1.
DR Pfam; PF07504; FTP; 1.
DR Pfam; PF01447; Peptidase_M4; 1.
DR Pfam; PF02868; Peptidase_M4_C; 1.
DR Pfam; PF04151; PPC; 2.
DR PRINTS; PR00730; THERMOLYSIN.
DR SUPFAM; SSF55486; Metalloproteases ('zincins'), catalytic domain; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zymogen {ECO:0000256|ARBA:ARBA00023145}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..718
FT /note="Peptidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5002327938"
FT DOMAIN 54..103
FT /note="FTP"
FT /evidence="ECO:0000259|Pfam:PF07504"
FT DOMAIN 202..337
FT /note="Peptidase M4"
FT /evidence="ECO:0000259|Pfam:PF01447"
FT DOMAIN 340..484
FT /note="Peptidase M4 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02868"
FT DOMAIN 523..593
FT /note="Peptidase C-terminal archaeal/bacterial"
FT /evidence="ECO:0000259|Pfam:PF04151"
FT DOMAIN 638..702
FT /note="Peptidase C-terminal archaeal/bacterial"
FT /evidence="ECO:0000259|Pfam:PF04151"
FT REGION 660..681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 330
FT /evidence="ECO:0000256|PIRSR:PIRSR623612-1"
FT ACT_SITE 412
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR623612-1"
SQ SEQUENCE 718 AA; 78699 MW; 9A40D3965CE5FB7D CRC64;
MKKNKITVLL LALAAVSAQN ALAAESINAR KHLKQHPVSG VEMHSVLGLS AEHSFRVKSK
RVFKNGKSKQ RMSQYYRGVP VWGQSVATEV SPMGVLSDIS GTFAQNIATD VSSVIPGLSE
AQVKSINRKK NGDTEVSHET AELIIYIGDD NRAHLAYKTD YVVYSETPRR PTAIIDADNG
VILLAYDAMA FAEATGPGGN EKTGQYYYGR DFPALNVTDD CRMDNDNVAT IDMNHATSGG
EIHQFTCPEN LYKPVNGGYS ALNDAHYFGG VVFDMYNDWY QSAPLQFKLA MRVHYGVDYE
NAFWDGQQMT FGDGLDRYYP LVSLDVVSHE ISHGFTEQNS GLAYFSQSGG INESFSDVMG
EVAKYYSRGS NDWHVGGDIF KADGALRYMD NPPQDGNSID HADDYYGFMN VHYSSGVFNK
AFYLLTNTPG WDIRMAGETY VVANQLYWQA TSSFEDGACG VYTAARDLGY NLNDVETAFN
GVGVAMCDEF SEERPPTPPE YTLLENGTVL TDLWSDDRVH LKYAIEVPEG ATTLDVAISG
PIVDTTYDNA DLVIQYEGIP TPVDNLCYPG QPDNNESCSF SNPEAGIWYI VIEAQVSFEQ
LTLSVAHDGS DIPNPGEGDS GTESGLSASR NQWLYRTLEV PEGMGTLDVS LTGGTGDASL
YLKHGSEPSN RNNDCRSRTD GNEESCIINA PDAGAWYIGL RGSGGSFDDV TMNWQYQP
//
