ID A0A0D8FTK2_9ACTN Unreviewed; 198 AA.
AC A0A0D8FTK2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=precorrin-2 dehydrogenase {ECO:0000256|ARBA:ARBA00012400};
DE EC=1.3.1.76 {ECO:0000256|ARBA:ARBA00012400};
GN Name=cysG {ECO:0000313|EMBL:KJE75587.1};
GN ORFNames=FEAC_26690 {ECO:0000313|EMBL:KJE75587.1};
OS Ferrimicrobium acidiphilum DSM 19497.
OC Bacteria; Actinomycetota; Acidimicrobiia; Acidimicrobiales;
OC Acidimicrobiaceae; Ferrimicrobium.
OX NCBI_TaxID=1121877 {ECO:0000313|EMBL:KJE75587.1, ECO:0000313|Proteomes:UP000032336};
RN [1] {ECO:0000313|EMBL:KJE75587.1, ECO:0000313|Proteomes:UP000032336}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=T23 {ECO:0000313|EMBL:KJE75587.1,
RC ECO:0000313|Proteomes:UP000032336};
RA Poehlein A., Eisen S., Schloemann M., Johnson B.D., Daniel R., Muehling M.;
RT "Draft genome of the acidophilic iron oxidizer Ferrimicrobium acidiphilum
RT strain T23.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Porphyrin-containing compound metabolism; siroheme
CC biosynthesis; sirohydrochlorin from precorrin-2: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005010}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJE75587.1}.
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DR EMBL; JXUW01000035; KJE75587.1; -; Genomic_DNA.
DR RefSeq; WP_052566374.1; NZ_JXUW01000035.1.
DR AlphaFoldDB; A0A0D8FTK2; -.
DR STRING; 1121877.FEAC_26690; -.
DR GeneID; 78373672; -.
DR eggNOG; COG1648; Bacteria.
DR OrthoDB; 9815856at2; -.
DR UniPathway; UPA00262; UER00222.
DR Proteomes; UP000032336; Unassembled WGS sequence.
DR GO; GO:0004325; F:ferrochelatase activity; IEA:InterPro.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0043115; F:precorrin-2 dehydrogenase activity; IEA:UniProtKB-EC.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0019354; P:siroheme biosynthetic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR028161; Met8-like.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR35330; SIROHEME BIOSYNTHESIS PROTEIN MET8; 1.
DR PANTHER; PTHR35330:SF1; SIROHEME BIOSYNTHESIS PROTEIN MET8; 1.
DR Pfam; PF13241; NAD_binding_7; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR SUPFAM; SSF75615; Siroheme synthase middle domains-like; 1.
PE 4: Predicted;
KW Lyase {ECO:0000313|EMBL:KJE75587.1};
KW Methyltransferase {ECO:0000313|EMBL:KJE75587.1};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000313|EMBL:KJE75587.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000032336};
KW Transferase {ECO:0000313|EMBL:KJE75587.1}.
SQ SEQUENCE 198 AA; 22418 MW; 50AECBDFBF1690BD CRC64;
MMVKLRLENR MVVVIGASDE AVQRANSFAN QGARVLLVGT PAGGWASLIS IQDDSSMSCR
YAKRPSRKDL KRAALVVATD RDDVINTWLS DKAKRYRFLL NTLDVPEYCD YYHVAIRRPH
LDIEIGVSTD GHSPAFASSL ATRLAKTVTD DDCHTYEVLK QIRQQLRQQG QSPSSLDWVQ
LELETRQSRL RETRQAQL
//
