ID   A0A0D8HH47_9ACTN        Unreviewed;       389 AA.
AC   A0A0D8HH47;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Sensor protein KdpD {ECO:0000313|EMBL:KJF16376.1};
DE            EC=2.7.13.3 {ECO:0000313|EMBL:KJF16376.1};
GN   Name=kdpD2 {ECO:0000313|EMBL:KJF16376.1};
GN   ORFNames=AXFE_27800 {ECO:0000313|EMBL:KJF16376.1};
OS   Acidithrix ferrooxidans.
OC   Bacteria; Actinomycetota; Acidimicrobiia; Acidimicrobiales;
OC   Acidimicrobiaceae; Acidithrix.
OX   NCBI_TaxID=1280514 {ECO:0000313|EMBL:KJF16376.1, ECO:0000313|Proteomes:UP000032360};
RN   [1] {ECO:0000313|EMBL:KJF16376.1, ECO:0000313|Proteomes:UP000032360}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Py-F3 {ECO:0000313|EMBL:KJF16376.1,
RC   ECO:0000313|Proteomes:UP000032360};
RA   Poehlein A., Eisen S., Schloemann M., Johnson B.D., Daniel R., Muehling M.;
RT   "Draft genome of the acidophilic iron oxidizer Acidithrix ferrooxidans
RT   strain Py-F3.";
RL   Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KJF16376.1}.
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DR   EMBL; JXYS01000086; KJF16376.1; -; Genomic_DNA.
DR   RefSeq; WP_052606469.1; NZ_JXYS01000086.1.
DR   AlphaFoldDB; A0A0D8HH47; -.
DR   STRING; 1280514.AXFE_27800; -.
DR   PATRIC; fig|1280514.3.peg.3653; -.
DR   OrthoDB; 9806130at2; -.
DR   Proteomes; UP000032360; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR   CDD; cd01987; USP_OKCHK; 1.
DR   Gene3D; 3.40.50.620; HUPs; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR   InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR   InterPro; IPR006016; UspA.
DR   PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR   PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR   Pfam; PF02702; KdpD; 1.
DR   Pfam; PF00582; Usp; 1.
DR   SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Reference proteome {ECO:0000313|Proteomes:UP000032360};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KJF16376.1};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   DOMAIN          20..227
FT                   /note="Signal transduction histidine kinase osmosensitive
FT                   K+ channel sensor N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02702"
FT   DOMAIN          249..360
FT                   /note="UspA"
FT                   /evidence="ECO:0000259|Pfam:PF00582"
SQ   SEQUENCE   389 AA;  43638 MW;  66F9F716F966AF67 CRC64;
     MEKTPFSNTD TENSFVEPAG KFRIYLGAAA GVGKTVAMLE EGIRRKSRGA DVVVGFVETH
     KRPFTLEKTL DFEIIPRKTI SYRGSTFQEM DLDAILARAP EVVLVDELAH TNVPESSTNE
     KRYQDILILL KSGISVITTV NIQHLESIAA AVEEIVGAKV AERVPDWVVR NADQIELVDS
     SPESLRRRLL HGNIYPQEKI ESALTHFFKF ENLSALRDIA LRFVADETEE EMLDYLRKIK
     IPGRWETSER IMVAVSGAPE SSFVLHRAAR MAQRAKTQLM VVHIKSADAN LNGSDLDVLK
     NECEKLDARW QDLYEDDVAK GIVEFALSAK VTQIVLGATR QNKWKRRLGN SILTKIMDNA
     GNQGIDVHII ARHRDSPNGD FTLNELTES
//