ID A0A0D8HMF7_9ACTN Unreviewed; 333 AA.
AC A0A0D8HMF7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 03-MAY-2023, entry version 22.
DE SubName: Full=Prephenate dehydrogenase {ECO:0000313|EMBL:KJF18276.1};
GN ORFNames=AXFE_08430 {ECO:0000313|EMBL:KJF18276.1};
OS Acidithrix ferrooxidans.
OC Bacteria; Actinomycetota; Acidimicrobiia; Acidimicrobiales;
OC Acidimicrobiaceae; Acidithrix.
OX NCBI_TaxID=1280514 {ECO:0000313|EMBL:KJF18276.1, ECO:0000313|Proteomes:UP000032360};
RN [1] {ECO:0000313|EMBL:KJF18276.1, ECO:0000313|Proteomes:UP000032360}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Py-F3 {ECO:0000313|EMBL:KJF18276.1,
RC ECO:0000313|Proteomes:UP000032360};
RA Poehlein A., Eisen S., Schloemann M., Johnson B.D., Daniel R., Muehling M.;
RT "Draft genome of the acidophilic iron oxidizer Acidithrix ferrooxidans
RT strain Py-F3.";
RL Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KJF18276.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JXYS01000020; KJF18276.1; -; Genomic_DNA.
DR RefSeq; WP_052604605.1; NZ_JXYS01000020.1.
DR AlphaFoldDB; A0A0D8HMF7; -.
DR STRING; 1280514.AXFE_08430; -.
DR OrthoDB; 9802008at2; -.
DR Proteomes; UP000032360; Unassembled WGS sequence.
DR GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR GO; GO:0008977; F:prephenate dehydrogenase (NAD+) activity; IEA:InterPro.
DR GO; GO:0004665; F:prephenate dehydrogenase (NADP+) activity; IEA:InterPro.
DR GO; GO:0006571; P:tyrosine biosynthetic process; IEA:InterPro.
DR Gene3D; 1.10.3660.10; 6-phosphogluconate dehydrogenase C-terminal like domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR046825; PDH_C.
DR InterPro; IPR046826; PDH_N.
DR InterPro; IPR003099; Prephen_DH.
DR PANTHER; PTHR21363; PREPHENATE DEHYDROGENASE; 1.
DR PANTHER; PTHR21363:SF0; PREPHENATE DEHYDROGENASE [NADP(+)]; 1.
DR Pfam; PF20463; PDH_C; 1.
DR Pfam; PF02153; PDH_N; 1.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS51176; PDH_ADH; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000032360}.
FT DOMAIN 5..291
FT /note="Prephenate/arogenate dehydrogenase"
FT /evidence="ECO:0000259|PROSITE:PS51176"
SQ SEQUENCE 333 AA; 36341 MW; 94B93B93E87D2288 CRC64;
MPGFKRVGII GLGQIGSSLM LGLKGSYEVY GFDLSETACA FGEANGIEIK ANLIEILESS
EIVFLAVPSF EVIRLLEMIS DLALKSPIVL VDMASTKLDI ETKVLSLNFD SRYVSYVGIH
PLAGNERPSF EGAELDLFRG RTMVVSSGSA SDPRSSLAVA QLIVHDLGSR VIFVNPAIHD
RVTNFTIQLP HVFAYLTSSF ANEVNDQVLL QTLSGNSFAG VTRVARSSPV MVGSFLYSNR
EILRHSLVNL SSKVDAILKA LDGDDAEEII EILKLYSPAK VDLIEERFAE TIALVDESSY
HLAVDRFSRE RYILDSIEAI DQELIVSGVT TSS
//
