ID A0A0D8JX74_COCIM Unreviewed; 566 AA.
AC A0A0D8JX74;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 22-FEB-2023, entry version 23.
DE RecName: Full=PWI domain-containing protein {ECO:0000259|PROSITE:PS51025};
GN ORFNames=CIMG_07832 {ECO:0000313|EMBL:KJF60878.1};
OS Coccidioides immitis (strain RS) (Valley fever fungus).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Onygenales; Onygenaceae; Coccidioides.
OX NCBI_TaxID=246410 {ECO:0000313|EMBL:KJF60878.1, ECO:0000313|Proteomes:UP000001261};
RN [1] {ECO:0000313|Proteomes:UP000001261}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=19717792; DOI=10.1101/gr.087551.108;
RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., Wortman J.R.,
RA Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., Zeng Q., Hung C.-Y.,
RA McMahan C., Muszewska A., Grynberg M., Mandel M.A., Kellner E.M.,
RA Barker B.M., Galgiani J.N., Orbach M.J., Kirkland T.N., Cole G.T.,
RA Henn M.R., Birren B.W., Taylor J.W.;
RT "Comparative genomic analyses of the human fungal pathogens Coccidioides
RT and their relatives.";
RL Genome Res. 19:1722-1731(2009).
RN [2] {ECO:0000313|Proteomes:UP000001261}
RP GENOME REANNOTATION.
RC STRAIN=RS {ECO:0000313|Proteomes:UP000001261};
RX PubMed=20516208; DOI=10.1101/gr.103911.109;
RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J.,
RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D.,
RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A.,
RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J.,
RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R.,
RA Taylor J.W., Rounsley S.D.;
RT "Population genomic sequencing of Coccidioides fungi reveals recent
RT hybridization and transposon control.";
RL Genome Res. 20:938-946(2010).
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DR EMBL; GG704913; KJF60878.1; -; Genomic_DNA.
DR RefSeq; XP_004445147.1; XM_004445090.1.
DR AlphaFoldDB; A0A0D8JX74; -.
DR GeneID; 4560215; -.
DR VEuPathDB; FungiDB:CIMG_07832; -.
DR OrthoDB; 5490322at2759; -.
DR Proteomes; UP000001261; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProt.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1390.10; PWI domain; 1.
DR InterPro; IPR002483; PWI_dom.
DR InterPro; IPR036483; PWI_dom_sf.
DR PANTHER; PTHR18806; RBM25 PROTEIN; 1.
DR PANTHER; PTHR18806:SF4; RNA-BINDING PROTEIN 25; 1.
DR Pfam; PF01480; PWI; 1.
DR SMART; SM00311; PWI; 1.
DR SUPFAM; SSF101233; PWI domain; 1.
DR PROSITE; PS51025; PWI; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW Reference proteome {ECO:0000313|Proteomes:UP000001261}.
FT DOMAIN 473..566
FT /note="PWI"
FT /evidence="ECO:0000259|PROSITE:PS51025"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 78..117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 141..307
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 343..370
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..25
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 141..174
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 248..307
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 566 AA; 63891 MW; 693DB2B6C1D4743F CRC64;
MQMRSLANLV SQIPVKKQQP PKEGGQQSQE DEKSKLLVVV DESSLKYIEQ YKTNSNQDPA
AVQSRIESAR AALATVLSEL ERPPTSQGDE TQTADRDGDV TMADGEDQNA ANSAEVVTIP
ITVEDELSDI PPEMRETVAK EIAAFRDRSN RRDLERLKRE EEIESLEKAR HGGSSRINRL
ASPPPSAPTG PAGGPNGIPL GPRDRGVPNA PAGPKGFGQQ IPKDYQKGVS FVNGLGINEE
EDDTDASDAE LERRRQAKKA AEAEKQFLDQ ERRWLNRERS RAAALEREKN RDKEEEKRME
EEKEDMAKRL REWNDDVEAS RKVEDYYADR GLWIRNRAAF RSREMAMDEA DRASEEREKA
RAMQQQERAR GMADDFLARQ AEEIESRVQA PREPQRFKLS LGAAAQKAQA STKRRTVAEV
EGLLEDEEET GTTAKRPLTA IKFDTAAEVA GLTDEERAQA ARQLAAEIPS DKEGLWKWEV
KWEFVDESIL GEQLKPFVEK KIMEYLGVQE QMLVDVVEEH VRKRGSPQEL VEQLDGALDE
EAEVLVKKLW RMIIFFSESE KRGLSG
//
