ID A0A0D8PYC8_9GAMM Unreviewed; 702 AA.
AC A0A0D8PYC8;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Tyrosine-protein kinase {ECO:0000313|EMBL:PSV99040.1};
DE EC=2.7.10.2 {ECO:0000313|EMBL:PSV99040.1};
GN ORFNames=C9I88_02350 {ECO:0000313|EMBL:PSV99040.1};
OS Photobacterium iliopiscarium.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Photobacterium.
OX NCBI_TaxID=56192 {ECO:0000313|EMBL:PSV99040.1, ECO:0000313|Proteomes:UP000241954};
RN [1] {ECO:0000313|EMBL:PSV99040.1, ECO:0000313|Proteomes:UP000241954}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NCIMB 13481 {ECO:0000313|EMBL:PSV99040.1,
RC ECO:0000313|Proteomes:UP000241954};
RA Butler K.;
RT "Whole genome sequencing of Histamine producing bacteria.";
RL Submitted (JAN-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-
CC [protein]; Xref=Rhea:RHEA:10596, Rhea:RHEA-COMP:10136, Rhea:RHEA-
CC COMP:10137, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616, ChEBI:CHEBI:46858,
CC ChEBI:CHEBI:82620, ChEBI:CHEBI:456216;
CC Evidence={ECO:0000256|ARBA:ARBA00001074};
CC -!- SUBCELLULAR LOCATION: Cell inner membrane
CC {ECO:0000256|ARBA:ARBA00004429}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004429}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the etk/wzc family.
CC {ECO:0000256|ARBA:ARBA00008883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PSV99040.1}.
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DR EMBL; PYLW01000002; PSV99040.1; -; Genomic_DNA.
DR RefSeq; WP_045036622.1; NZ_PYOP01000006.1.
DR AlphaFoldDB; A0A0D8PYC8; -.
DR GeneID; 70037816; -.
DR OrthoDB; 9775724at2; -.
DR Proteomes; UP000241954; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0045226; P:extracellular polysaccharide biosynthetic process; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR CDD; cd05387; BY-kinase; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR025669; AAA_dom.
DR InterPro; IPR032807; GNVR.
DR InterPro; IPR003856; LPS_length_determ_N_term.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR005702; Wzc-like_C.
DR NCBIfam; TIGR01007; eps_fam; 1.
DR PANTHER; PTHR32309; TYROSINE-PROTEIN KINASE; 1.
DR PANTHER; PTHR32309:SF13; TYROSINE-PROTEIN KINASE ETK-RELATED; 1.
DR Pfam; PF13614; AAA_31; 1.
DR Pfam; PF13807; GNVR; 1.
DR Pfam; PF02706; Wzz; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cell inner membrane {ECO:0000256|ARBA:ARBA00022519};
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:PSV99040.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:PSV99040.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius};
KW Tyrosine-protein kinase {ECO:0000256|ARBA:ARBA00023137}.
FT TRANSMEM 35..57
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 430..454
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 17..109
FT /note="Polysaccharide chain length determinant N-terminal"
FT /evidence="ECO:0000259|Pfam:PF02706"
FT DOMAIN 372..452
FT /note="Tyrosine kinase G-rich"
FT /evidence="ECO:0000259|Pfam:PF13807"
FT DOMAIN 529..654
FT /note="AAA"
FT /evidence="ECO:0000259|Pfam:PF13614"
FT COILED 274..308
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 702 AA; 76513 MW; 0974FF3E5231B62B CRC64;
MTAISNKPVK STSTANEEID LGKIFGILRD SKKSILAITI VFTLLGLIYS IFATPIYKSD
VLIKVDSKSD GSPAYGESME KEFLTDSSAV TEMELIKSRR VIGKTVDKLN LTTSVVPDYL
PIIGKGIARL AGKESSATVA RFIMPANAKS NSYQLKIVNV DTGEFVLTDE DNASVELKGF
VGQPVEEQGY NLLITALTGA NNDTFTVKKL PRFDVIAYYQ KSLSVTEKGK DTGIVLISLD
GQNRLKTQKV LNSISNNYYQ LNADRAAASA NKSLEFLNER LPAIKTELTN AENKLNGYRE
ANQSVNIEMQ AKSSLDELVA LDGQINELSF QEADISRSYT KEHPLYKALI EKRNDLQAQK
TRLTRKIDQM PETQREIIRL TRHVDVNQQT YMQILNKIQE LDIVKASSSA SVQIIDSASS
SAKPVAPNRV MLVVGPAILG LILGVLIALF RVILNNKVVD PQQLKAIGLP VFALVPKTKK
LPNAILAEVD SSDISIEALR TLRNRIFLAM ENTNNNTVLL TSASSITKSG KTFVITNVAV
LMAEAGKRVL IIDADMRKGK IAAALNGKQA NGLAELLSGK NDLKTVVKTS SITNLDYISG
GEKPNSPAEL LIHNEFKTLL AWGAEHYDVV IVNTPPVLAV VDAAIIGAAV GTTVMVGSYG
IDSLKEIEQA KQSFEDNGVE VNGFVLNNTI KKTSNQAIFK KY
//
