ID A0A0D8X937_DICVI Unreviewed; 427 AA.
AC A0A0D8X937;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Transmembrane protein 129 {ECO:0008006|Google:ProtNLM};
GN ORFNames=DICVIV_12930 {ECO:0000313|EMBL:KJH41105.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH41105.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH41105.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH41105.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMEM129 family.
CC {ECO:0000256|ARBA:ARBA00007332}.
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DR EMBL; KN716904; KJH41105.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8X937; -.
DR STRING; 29172.A0A0D8X937; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0061630; F:ubiquitin protein ligase activity; IEA:InterPro.
DR GO; GO:0016567; P:protein ubiquitination; IEA:InterPro.
DR InterPro; IPR018801; TM129.
DR PANTHER; PTHR31322; E3 UBIQUITIN-PROTEIN LIGASE TM129; 1.
DR PANTHER; PTHR31322:SF2; E3 UBIQUITIN-PROTEIN LIGASE TM129; 1.
DR Pfam; PF10272; Tmpp129; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..61
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 102..123
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 138..159
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 427 AA; 48852 MW; EE6809A03E2F164E CRC64;
MAWNGAIISI FFSSIVISQQ VVGRTLTQDE WNTLQAAYVL PNSTIFFHAL VFTICLLLLL
YPPDAFMGAG LSFDNLTYGY LGSSEANILE FHCRRVVLTR SLVASSPYSL LIQLSVLVLS
LYFAEEYAVL FTSHPTRVIH YFTLISPFFA LGGLAYLIYH TMTGFRSLTA MKILKDYGYD
SPARLHDSFK RIQSNVSKLI ITDSWLFHCS RFNFVVVKVS DAHFRVIRAE DTMNMLHHAL
GMNQYLTVAV SLPTHFQHLN FQFKINNVSM RDLERKLGTN RIEFSQEVQL KMSLTDMFIE
AFLDQAKKNP RFHQYIKEEL EPCLGCSDKL SNIKLSMGCN EIMRDPEQDE FRTDCSPCHC
RPMWCVSCMA RIFLAKQNQS RSTVWLEGTC PCPTCRATFC VMDVSLLSFF DDENLTDATI
VRNEGKQ
//
