ID A0A0D8XCW7_DICVI Unreviewed; 935 AA.
AC A0A0D8XCW7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=ABC transporter, ATP-binding protein {ECO:0000313|EMBL:KJH41504.1};
GN ORFNames=DICVIV_12521 {ECO:0000313|EMBL:KJH41504.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH41504.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH41504.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH41504.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; KN716811; KJH41504.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8XCW7; -.
DR STRING; 29172.A0A0D8XCW7; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0042221; P:response to chemical; IEA:UniProt.
DR CDD; cd18577; ABC_6TM_Pgp_ABCB1_D1_like; 1.
DR CDD; cd03249; ABC_MTABC3_MDL1_MDL2; 1.
DR Gene3D; 1.20.1560.10; ABC transporter type 1, transmembrane domain; 4.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR039421; Type_1_exporter.
DR PANTHER; PTHR24221; ATP-BINDING CASSETTE SUB-FAMILY B; 1.
DR PANTHER; PTHR24221:SF243; P-GLYCOPROTEIN RELATED; 1.
DR Pfam; PF00664; ABC_membrane; 3.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF90123; ABC transporter transmembrane region; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50929; ABC_TM1F; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000313|EMBL:KJH41504.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 102..127
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 177..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 845..870
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 882..900
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 102..263
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT DOMAIN 353..628
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 711..905
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000259|PROSITE:PS50929"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 935 AA; 104678 MW; 1F720D04CE780188 CRC64;
MKRDISAYEA PGDGNGEIEK IENDKTDVVR KNGVQAKFSG DVILQDFDND DDEGSKVTSA
ETSNWEKFIN YLLCRSDLAK QTLKGKPVPF LKLFRYSTKL DVFMLIVGTI GAALNGCCQF
LCFYNVCTRQ IANIRLQYLK AVLRQNAAWL DRHHCGVLTT QLNDNIERIR EGVGDKMGLL
IRGFSMFIVA LIISFSTQWK LALFMSPVAP LSCFCMSVMS RKVAELTSKE LKDVGKAGAI
AEESVLGVRT VQALNGQEEM IEKSKACRSR MHMFRFGGHL LEIGAIQDTG DVITVVISMM
MGAYFLGLIS PHLMVLLNAR VSAAVIYDTI DRRPKIDVYS TSGKLPGNIK GDIEFNNVHF
RYPTRKDVKV LNGLTLKIHN GETVAFVGHS GCGKSTAVGL ITRLYEAESG EVSFPCWLLQ
CINNLPIRLI RARIIWGMIR THMVKIDAND VCDVNLEWLR NTVEWLRNTV GIVEQEPTLF
NGTIEENLKV GNPTITSSEM IEVCKTANAH DFITQLPKGY STIIGDGAVQ LSGGQKQRIA
IARTLARNPK ILLLDEATSA LDANSECVVQ QALDVASKGR TTIVIAHRLS TIRKADKIMV
FEKGVIAEQG THQELINLDG RYAKLVRAQQ FHSDENEDCL LNDDIIPDLP VVSDVSRKAS
ETPSIGAETF IRGALSVQSF RNSLIMSGGD EVMMAMESSQ FEQQVKEEMK RNLLFAKVSE
QLTLSLRIKT FRSILYQDAA YFDNPEHSPG RLITRLATDA PNIKVYNVRR SYGYARSNYS
NDKLADDKTN QAGKLNIFFQ LSIEIIENIR TVQLLTREKY FYEKYMEALK QEKNKEIKKG
YYEGINYALS QSFICFSLGF AYAIGIPLIT QWQYDSDKVY RAVFSVLLAC IGVMNCSTFF
PEFTKARTAA GMIFNMINRQ SKTADIDEGL QLVMS
//
