ID   A0A0D8XH04_DICVI        Unreviewed;       279 AA.
AC   A0A0D8XH04;
DT   27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT   27-MAY-2015, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Pyridoxal-phosphate dependent protein {ECO:0000313|EMBL:KJH43002.1};
GN   ORFNames=DICVIV_11012 {ECO:0000313|EMBL:KJH43002.1};
OS   Dictyocaulus viviparus (Bovine lungworm).
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX   NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH43002.1, ECO:0000313|Proteomes:UP000053766};
RN   [1] {ECO:0000313|EMBL:KJH43002.1, ECO:0000313|Proteomes:UP000053766}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH43002.1,
RC   ECO:0000313|Proteomes:UP000053766};
RA   Mitreva M.;
RT   "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Proteomes:UP000053766}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX   PubMed=26856411; DOI=10.1038/srep20316;
RA   McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA   Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA   Sternberg P.W., Gasser R.B., Mitreva M.;
RT   "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT   lungworm biology and support future intervention.";
RL   Sci. Rep. 6:20316-20316(2016).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the serine/threonine dehydratase family.
CC       {ECO:0000256|ARBA:ARBA00010869}.
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DR   EMBL; KN716603; KJH43002.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A0D8XH04; -.
DR   STRING; 29172.A0A0D8XH04; -.
DR   Proteomes; UP000053766; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:UniProt.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   CDD; cd01562; Thr-dehyd; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR43050; SERINE / THREONINE RACEMASE FAMILY MEMBER; 1.
DR   PANTHER; PTHR43050:SF1; SERINE RACEMASE; 1.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
PE   3: Inferred from homology;
KW   Pyridoxal phosphate {ECO:0000256|ARBA:ARBA00022898};
KW   Reference proteome {ECO:0000313|Proteomes:UP000053766}.
FT   DOMAIN          32..270
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
SQ   SEQUENCE   279 AA;  30221 MW;  05D655D419A5D470 CRC64;
     MCKIENDRGL SGCEVYMKCE HLQKTGVILF SVTHSSGNHG QGLAWAASQV GVLCYVAVPR
     NAPPSKMEAM IEYGAKVELC DATVKSREDT CARLAKDLSY CIVEPFDDSN IICGQGTIGA
     EIIEQLPDVD AIFLAIGGGG MASGIVAYMN EVKPSVKVFL IEPQGKHLAV YLKSGVLTMK
     RDVVDTIADG IRVLKIGRNC YPILKSCSDN VITVQFTVLQ TDDEIRVALR LIWTRTKQRV
     EPSAAVPLAG LLKISPSDHR LKKVVLVLCG GNVDLDFVP
//