ID A0A0D8XHX7_DICVI Unreviewed; 1127 AA.
AC A0A0D8XHX7;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=NF-X1 type zinc finger {ECO:0000313|EMBL:KJH41941.1};
GN ORFNames=DICVIV_12071 {ECO:0000313|EMBL:KJH41941.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH41941.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH41941.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH41941.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the NFX1 family.
CC {ECO:0000256|ARBA:ARBA00007269}.
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DR EMBL; KN716734; KJH41941.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8XHX7; -.
DR STRING; 29172.A0A0D8XHX7; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:UniProtKB-UniRule.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd06008; NF-X1-zinc-finger; 5.
DR InterPro; IPR034078; NFX1_fam.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR000967; Znf_NFX1.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR12360; NUCLEAR TRANSCRIPTION FACTOR, X-BOX BINDING 1 NFX1; 1.
DR PANTHER; PTHR12360:SF12; TRANSCRIPTIONAL REPRESSOR NF-X1; 1.
DR Pfam; PF01424; R3H; 1.
DR Pfam; PF01422; zf-NF-X1; 7.
DR SMART; SM00438; ZnF_NFX; 9.
DR SUPFAM; SSF82708; R3H domain; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51061; R3H; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 256..306
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 913..980
FT /note="R3H"
FT /evidence="ECO:0000259|PROSITE:PS51061"
FT REGION 1..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1014..1043
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1127 AA; 127208 MW; 9B922C0CDCCC6CA7 CRC64;
MDHGKSSAVV GPVSSKKIEY RRRQRGRRGG NNGGEQTRCI QNFSNEDGTS YQRVCFQATN
SNFGLDHGPS QNSYEDRTRG WQVAVNSDSR SEGATEFNVT GQFTPQNQAL QGGSVSQGDN
NAHIQSSRYM FNPNAPPFIP QAFHSIRREP IDIQCRQQNY TAPRFYTHNE HQFQKSRKSV
RGRIRGCTSD GPQISPNQNQ IRTRGSDKAY INRANRNKLY RSNHRKAQKD VLRQGESMRA
ITGRLIHQLE NRSYECAICC QVILPKQSIW SCTTCYHIFH ISGGCITNWA KRSKEDDNGW
RCPTCQTKYS EIPYTYFCFC RKQRNPTNYI HDTPHSCGDI CGNKRAPNCT HPCNELCHPG
PCPECPVMIT RSCNCGNIQK TIRCGSVVEI KCDKVCDRLL GCGVHRCVRV CHDGECGQCE
VVVQQSCFCG SSSREMLCWE KGNVDNYSCG CNCTGMYKCG VHRCTRKCHM TDEFGCGPCP
YSPERISHCP CGRCSLEELK LERLSCSDPI PTCKNVCGKV LECGSAGNNH RCRALCHTGE
CPPCKLNTCV ICRCKQMRRT LTCVEYLQSK GMDDFLCMKR CKKRKSCGIH KCQELCCVQT
EHICLQVCNK RLSCGLHFCE NICHAGQCPR CLNSSFEEQY CHCGRTMRPP PIPCGSPLPE
CNELCVRPHR CNHPVTHRCH GDERCPPCTV LVERMCYGNH EMRMNVPCHI DAVSCGRLCE
KPLTCGVHYC NRSCHPGDCI KVDEKCSRPC MVLRRSCEHP CALPCHGTSL CPESECQYLL
GVTCECGKRR SQMKCCEFVK VMDRLRAIEA EELNESDPLG GIGLIKRSPS TEKLNCMPCD
DECKKLARNK KLAEALELVT DDNGDLERMP SITFTEYLKA ELRTNASFVL DVELAFTNLI
GRLEDVNESL SIVDLITLLI ELAVMFPFQP TYLGASLNYN FQPMSLEKRR FIHDYATFFF
LTSVSVDDPP KRSVIVTAKR GISRAPLVLL TSLQKNPLVL NLRGSSTLRG NIDEEDRRRS
TTGEIKDIQN GSRMKALRGS RPVKKRMAPQ IPCTLPLPQF NHFAVLKSDD EEAGYSSDQH
PTQMEDKTIL ATNMDWWDDE ERVSSFGDIS GIVLLLKELV LKVCEEM
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