ID A0A0D8XPF2_DICVI Unreviewed; 387 AA.
AC A0A0D8XPF2;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=RhoGAP domain protein {ECO:0000313|EMBL:KJH45637.1};
GN ORFNames=DICVIV_08315 {ECO:0000313|EMBL:KJH45637.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH45637.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH45637.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH45637.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
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DR EMBL; KN716396; KJH45637.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8XPF2; -.
DR STRING; 29172.A0A0D8XPF2; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd00159; RhoGAP; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR PANTHER; PTHR15228:SF25; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053766}.
FT DOMAIN 6..201
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 222..275
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..247
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 387 AA; 44872 MW; B42E94C11EC1DA3A CRC64;
MSIFGVSLQG HLELQERSIP LIIESSIDEL QKRGMRVKGI YRTCGVKSKI EEICEAFECC
SQNSTVDLSH VHPMNLASVV KLYLRKLPEP LMTHELYKDW INFGIKCIDD MGETHLDELT
RLVNRLPRFN YETLKHLMLH LNRVTWFHES NLMSPSNLST VVAPSLVWQP PNSFDHTSAI
IDAQHANRTV QCFITHAFLI FGVDRTKDWE EFFVKYALEE PPKEEDNGNV SDDEDIVDED
DSEDDEQLFV PQPPTPDLLK STRRGRADED PINCQASPDY LKRRFERSDR RQKRRSYTTS
ILITSNAERP IPIAKQKLVQ SILIDLVTDR FSNFFDSSAG SMIPLLLNRV IFPRRNFNTT
PYSKSSIIWL SILYDIDFYI LVSFYFV
//
