ID A0A0D8XZZ6_DICVI Unreviewed; 580 AA.
AC A0A0D8XZZ6;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Patched family protein {ECO:0000313|EMBL:KJH49457.1};
GN ORFNames=DICVIV_04394 {ECO:0000313|EMBL:KJH49457.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH49457.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH49457.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH49457.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- SIMILARITY: Belongs to the patched family.
CC {ECO:0000256|ARBA:ARBA00005585}.
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DR EMBL; KN716234; KJH49457.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8XZZ6; -.
DR STRING; 29172.A0A0D8XZZ6; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR10796; PATCHED-RELATED; 1.
DR PANTHER; PTHR10796:SF91; SSD DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR PROSITE; PS50156; SSD; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 191..210
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..285
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 306..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 472..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 190..364
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 580 AA; 65633 MW; 830846B69DC56940 CRC64;
MSSEERSNRV YGIVLRFCDR TSSPYLGSYL DDIERLEADV AINITFPMQE QWRTNNTEII
NDTVSFQELF IQNLCMNWYG ECYRQTSLIT LLKHRRELEE RGIAVSYPQA NPGGTPIYLA
FNVGECESDE AMVFLRFDTP AMDAMAKKWE DEAAFYVREK YGDNPHIKCH IKHSRIVDQG
LTNNANRLKP YFTVTVIVLI TFTSLYSLKW NINNTNGNLH VSVDWLRSKP ILALGGVLSS
GLAILSGIGL LLWCGMFFAE ITLVAPFLVL SIGVDDMFIA VAAWHNTELK YPGNSPTVLK
KRMCEAISES SVAVFITSIT DVLSFGVGTF TDIMAVEGFC AMTSACMFFT WLYQITFFAG
LMVISAKVEL AGRNSVLPCL KTKDIYAEQI DNEKCSVQHR ITNCKGEKCD VKIFAANGVP
HLYKNSSEMS DNVEERLSKT KKSVVQARNR GKMGLFFRNY YVPFLLDLRT KIAVAMAFVI
YLAISIYGIS VMEQGLDYDK LLLQTDPLVE AFAREIELFP SGDQIEIAIK NAPDMSIPDN
RRRIEEIAQK FEQISYSKTF LTCSDQFTCN PNLYNYNTTC
//
