ID A0A0D8Y3U0_DICVI Unreviewed; 1087 AA.
AC A0A0D8Y3U0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Importin-beta protein {ECO:0000313|EMBL:KJH51548.1};
GN ORFNames=DICVIV_02285 {ECO:0000313|EMBL:KJH51548.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH51548.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH51548.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH51548.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR EMBL; KN716181; KJH51548.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8Y3U0; -.
DR STRING; 29172.A0A0D8Y3U0; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 48..114
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
SQ SEQUENCE 1087 AA; 123882 MW; 96AAF6616065BB43 CRC64;
MAALTATPMV ILEEAKKQFQ EDGKLNVQLL DQVVTMMNRA TGEEQKIANM ILVELKENPN
SWTKVDAILE YSDLAESKYF ALQILESVIQ TKWKSLPLVQ RDGIKGFIVQ FILKLSESRI
ESEKNPLLLH KLNLVLVQIV KQDWPKNWPS FITDIVESSK TNDSICVNNM NILSLLSEEV
FDFGSQHLTQ AKEQHLKQQF CGQFQEVFTL CITILEKCPA NSIVEATLKT LHRFLSWIPV
GYVFETNITQ LLSENFLSLE VYRVVTLQCL TEISMIQIET EDNSYKDKLC AMFCATIKEI
GSLLGERANL ATAYQNGTDE DQKFISCLAQ FLVAFLKDHS ALVESPNPVC PQVTEYHMYA
IELLLSISQV EDVEIFKVCL DYWCALTSEL YRLNPFAPPS PPIAISFSCG GACAGKEHPR
RKLYKEHLSN LRTIMISRMA KPEEVLVVEN DQGEVVREIV KDTDSITLYK NMRECLVYLT
HLDCKDTEQK MTEKLASQVN GSEFSWKNLN TLCWAVGSIS GTMVEEDEKR FLVLVIRDLL
GLCEQKRGKD NKAVIASNIM YVVGQYPRFL RAHWKFLKTV INKLFEFMHE THEGVQDMAC
DTFIKIAMKC KRHFVIMQFG EQTPFIDEML KNLSGIICDL APSQVHVFYE AVGHIISSAS
DEPNQQADLI EKLMALPNSV WDEIIANAGE NMSVLEDQEV VRNLLNILKT NVACCKATGN
PFITQLSRLY IDLLSLYRIL SEKVSTAVEQ NGQEVLKMPL LKTMRAVKRE ILILISTWVA
SAKDKQMVLE NIVPPLFDAV LFDYQKNVPA AREPKVLSLL SIIVTKLGSM LASQVPQILA
AVFECTLAMI NKDMEAFPEH RTNFFQLIHA LTVECFQVFL ALPQEQLSYI IDAVVWAFQH
SMRNVAEIGL DILKDMLDRV EYLPRHQSQP FYKRFYMQIL QHVLAVVADS SQVHVAGVTY
YAEVLCRLFK ACEFLITVPL NDENPEQSNV DYIYEYIANI FVQHFTNLTE DQIRVIIKGF
FSFNTDPSGM RNHLRDFLVQ IKEFNGEDTS DLFLEEREAE IQAAQAKKNA IPGMCGPNNI
VDEDEMH
//
