ID A0A0D8Y4S5_DICVI Unreviewed; 667 AA.
AC A0A0D8Y4S5;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=C2 domain protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=DICVIV_04313 {ECO:0000313|EMBL:KJH49581.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH49581.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH49581.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH49581.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
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DR EMBL; KN716230; KJH49581.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8Y4S5; -.
DR STRING; 29172.A0A0D8Y4S5; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0045202; C:synapse; IEA:GOC.
DR GO; GO:0019992; F:diacylglycerol binding; IEA:InterPro.
DR GO; GO:0007268; P:chemical synaptic transmission; IEA:InterPro.
DR CDD; cd08395; C2C_Munc13; 1.
DR Gene3D; 1.10.357.50; -; 1.
DR Gene3D; 1.20.58.1100; -; 2.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR InterPro; IPR000008; C2_dom.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR010439; MUN_dom.
DR InterPro; IPR014770; Munc13_1.
DR InterPro; IPR014772; Munc13_dom-2.
DR InterPro; IPR027080; Unc-13.
DR PANTHER; PTHR10480; PROTEIN UNC-13 HOMOLOG; 1.
DR PANTHER; PTHR10480:SF12; UNC-13, ISOFORM E; 1.
DR Pfam; PF00168; C2; 1.
DR Pfam; PF06292; MUN; 2.
DR SMART; SM00239; C2; 1.
DR SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR PROSITE; PS50004; C2; 1.
DR PROSITE; PS51258; MHD1; 1.
DR PROSITE; PS51259; MHD2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000053766}.
FT DOMAIN 39..182
FT /note="MHD1"
FT /evidence="ECO:0000259|PROSITE:PS51258"
FT DOMAIN 285..468
FT /note="MHD2"
FT /evidence="ECO:0000259|PROSITE:PS51259"
FT DOMAIN 483..610
FT /note="C2"
FT /evidence="ECO:0000259|PROSITE:PS50004"
SQ SEQUENCE 667 AA; 76327 MW; E42E6F61B0F04310 CRC64;
MMRVIEDDKT VYGPSLNQFP QELNIGHLSA GTLWTLYKMD LKMALEEHAT TKKCPTPEYM
NLYFKVKGFY FKYVSDLPQY KHSIPEFPAW FIPFVMDWLN ENDEHSMDIL RNAYNRDKAD
NFPQTSDHTR FSNSVVDVFT QLNEALKLLK QMDCPNPIVY ADMMKRFSKT LNKVLLAYAD
MVHKDFPKFS SNEKLACILM NNVQQLRVQL EKIYETMGGA DLDPACSQVL TNLQKKLNSV
LDKLSGQFVV TLEPMIHEQI NKLGILLSKI KGPQLQKTQL AAEVDAVLEP LMDLLEGSLQ
RYFQQCEKTV LKYILKELWR ITIVTMEKTV VLPPLADKTL LKQLPNAKIQ DVTKLMSTNI
QNIKGMSSVK EMMDMARECE RSLTPKQCTV LDAALDAIKG LDGHTLYQDD LLCLFHGTFN
SVYHFSECFH AGGQGLKKSF FEKSPELQSL KYALSLYTQT TEQLIKTFIT SQKQQDLPSQ
EQPVGEVSVQ VDLFSHPGTG EQKVTVKILA ANDLRWQTSS VFKPFVEVHL VGPHLSDKKR
KMATKSKPGN WAPKFNETFH FFLGNEGEPE HYELMFQVKD YCFAREDRIV GVGVLQLANV
VEQGSCAMWV QLGQRLHIDE TGLILLRILS QRQTDEVARE FVRLKSECRH ETESTLVTST
SVQNINR
//
