ID A0A0D8Y6Z0_DICVI Unreviewed; 356 AA.
AC A0A0D8Y6Z0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=DICVIV_01858 {ECO:0000313|EMBL:KJH51967.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH51967.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH51967.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH51967.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
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DR EMBL; KN716173; KJH51967.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8Y6Z0; -.
DR STRING; 29172.A0A0D8Y6Z0; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0003990; F:acetylcholinesterase activity; IEA:UniProtKB-EC.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR019819; Carboxylesterase_B_CS.
DR InterPro; IPR000997; Cholinesterase.
DR PANTHER; PTHR43918; ACETYLCHOLINESTERASE; 1.
DR PANTHER; PTHR43918:SF9; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR PRINTS; PR00878; CHOLNESTRASE.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Neurotransmitter degradation {ECO:0000256|ARBA:ARBA00022867};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766};
KW Serine esterase {ECO:0000256|ARBA:ARBA00022487};
KW Signal {ECO:0000256|RuleBase:RU361235}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT CHAIN 18..356
FT /note="Carboxylic ester hydrolase"
FT /evidence="ECO:0000256|RuleBase:RU361235"
FT /id="PRO_5005115635"
FT DOMAIN 27..349
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
SQ SEQUENCE 356 AA; 39926 MW; 4D5037802F8F77A2 CRC64;
MITRVLFTSI CGIFAQATSN QNYIPVEVET RLGKIRGQQT IFLHKNVRSF LSVPYAEPPI
GNQRFRPPEP KKPWTETITA DVLSPACYQG RDMYNTSFWG SEMWNHNTPI SEDCLFLNIW
TPAEAYNLTV MVWLFGGGYY SGSPSLILYD GKALALFGNV VVVNVNYRVG PFGYLFMDDD
EAPGNVGMLD QQLALYWIRD NIFNFGGNPT RITLFGESAG AASIVAHLIA PGSENLFKNG
ILQSGSLDNK WSMDTPARAL DKGIQLSNLV GCNRTQVKDT IACLRSAPAQ LLVDNIWNIE
LNFLEFPFVI VSRDRNFFRH KDGFMSLRTG QYVHHVNLMF GINHDEGDSS FSFCSL
//
