ID A0A0D8YAH0_DICVI Unreviewed; 932 AA.
AC A0A0D8YAH0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=EF hand {ECO:0000313|EMBL:KJH53004.1};
GN ORFNames=DICVIV_00873 {ECO:0000313|EMBL:KJH53004.1};
OS Dictyocaulus viviparus (Bovine lungworm).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Metastrongylidae; Dictyocaulus.
OX NCBI_TaxID=29172 {ECO:0000313|EMBL:KJH53004.1, ECO:0000313|Proteomes:UP000053766};
RN [1] {ECO:0000313|EMBL:KJH53004.1, ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|EMBL:KJH53004.1,
RC ECO:0000313|Proteomes:UP000053766};
RA Mitreva M.;
RT "Draft genome of the bovine lungworm Dictyocaulus viviparus.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000053766}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HannoverDv2000 {ECO:0000313|Proteomes:UP000053766};
RX PubMed=26856411; DOI=10.1038/srep20316;
RA McNulty S.N., Strube C., Rosa B.A., Martin J.C., Tyagi R., Choi Y.J.,
RA Wang Q., Hallsworth Pepin K., Zhang X., Ozersky P., Wilson R.K.,
RA Sternberg P.W., Gasser R.B., Mitreva M.;
RT "Dictyocaulus viviparus genome, variome and transcriptome elucidate
RT lungworm biology and support future intervention.";
RL Sci. Rep. 6:20316-20316(2016).
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DR EMBL; KN716157; KJH53004.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D8YAH0; -.
DR STRING; 29172.A0A0D8YAH0; -.
DR Proteomes; UP000053766; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR GO; GO:0045104; P:intermediate filament cytoskeleton organization; IEA:InterPro.
DR CDD; cd00176; SPEC; 1.
DR Gene3D; 1.20.58.60; -; 3.
DR Gene3D; 1.10.238.10; EF-hand; 1.
DR Gene3D; 3.30.920.20; Gas2-like domain; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR003108; GAR_dom.
DR InterPro; IPR036534; GAR_dom_sf.
DR InterPro; IPR043197; Plakin.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR23169; ENVOPLAKIN; 1.
DR PANTHER; PTHR23169:SF23; SHORT STOP, ISOFORM H; 1.
DR Pfam; PF02187; GAS2; 1.
DR Pfam; PF00435; Spectrin; 1.
DR SMART; SM00243; GAS2; 1.
DR SMART; SM00150; SPEC; 3.
DR SUPFAM; SSF47473; EF-hand; 1.
DR SUPFAM; SSF143575; GAS2 domain-like; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
DR PROSITE; PS50222; EF_HAND_2; 1.
DR PROSITE; PS51460; GAR; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Reference proteome {ECO:0000313|Proteomes:UP000053766}.
FT DOMAIN 673..708
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 749..821
FT /note="GAR"
FT /evidence="ECO:0000259|PROSITE:PS51460"
FT REGION 878..932
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 878..896
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 898..913
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 914..932
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 932 AA; 107545 MW; 57541CD7BFE4BC42 CRC64;
MNKEWKELNS ILNEFADHLE QAKVEAEKAG RDAEQLIAWL DDIESLLATK RPVGGLPESA
QAQLNDFLLL KENVIIQNTL SLEAYIEDVD NKVCDIESST DSWIGRNQTF IKNKWIKVKK
LCADREKKLQ LALEEAVALD VSMHDTAEWL TVAEKRLAEM KLCADREKKL QLALEEAVAL
AVSMHDTAEW LTVAEKRLAE MDPISHLPDV LETQLREDEK WTEEVALRIF LIRRKRLMAE
QQAAGTRLQY YCEKKDSVPI KNGLVSLKHR FEKVSNRTAD RTKQIQAEMS SRQRDFDLTY
KRGLILIDHA PRSETKQITQ CNNDAKKRWT EVLEKTNEKY IATEKALLDS SAFDEAIKEL
ELWIDNELEK SASADSRVAG DVDFVRMLSD EHKKRDVEWC AKEIALQTIL SKADQLSAKV
SDEKNNIEAS CNRVMEKWSR LKELSSVYSI ALRDAATKAA DFDAQIHGIL DWLVEIESRL
AVSSMDLTKA LCVVEDLKVP FSTDSFSSLQ LSYIVLVFSK ADFRNNREKR DSCIQTGKEI
QANCCPLAEQ TLRHWIRVVD SRWKKREELN KILSQQLPSK LDMISEMQQS HNDFYSKLRE
KQALIDDIIK NSRRGKKNAA AVKLCEDWKQ LWLDSIGYQA ALEGQRQMLE EMCRLEGWRW
EVWKEQYVEW NDHRKARVSD LFRRIDRNHT GNIPRETFID GILTSKFPSS RLELNKVADL
FDKGDGLINS KEFIDALRFD RFHERKPLTE HEKVNEEIAK QKNACSCCQQ YKIEKVADGH
YRFGDTQIKR MVRILRSTVM VRVGGGWEPL DIFLSKHDPC RTRGRLNIDM FYKDVAPSNA
IDTMRAFTRG RPRSVPCSSG PVVKVREKTE RSIPMFPHRR DLNKNDASEL EHSIIKESEG
SPTASISRPL SRNTDSAIDD KPTRIPSIRK KD
//
