ID A0A0D9NQF0_METAN Unreviewed; 580 AA.
AC A0A0D9NQF0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 08-NOV-2023, entry version 22.
DE RecName: Full=Carotenoid cleavage dioxygenase 1 {ECO:0008006|Google:ProtNLM};
GN ORFNames=H634G_08507 {ECO:0000313|EMBL:KJK76101.1};
OS Metarhizium anisopliae BRIP 53293.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=1291518 {ECO:0000313|EMBL:KJK76101.1, ECO:0000313|Proteomes:UP000054544};
RN [1] {ECO:0000313|Proteomes:UP000054544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRIP 53293 {ECO:0000313|Proteomes:UP000054544};
RX PubMed=25102932; DOI=10.1186/1471-2164-15-660;
RA Pattemore J.A., Hane J.K., Williams A.H., Wilson B.A., Stodart B.J.,
RA Ash G.J.;
RT "The genome sequence of the biocontrol fungus Metarhizium anisopliae and
RT comparative genomics of Metarhizium species.";
RL BMC Genomics 15:660-660(2014).
CC -!- COFACTOR:
CC Name=Fe(2+); Xref=ChEBI:CHEBI:29033;
CC Evidence={ECO:0000256|PIRSR:PIRSR604294-1};
CC Note=Binds 1 Fe(2+) ion per subunit. {ECO:0000256|PIRSR:PIRSR604294-1};
CC -!- SIMILARITY: Belongs to the carotenoid oxygenase family.
CC {ECO:0000256|ARBA:ARBA00006787}.
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DR EMBL; KE384747; KJK76101.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D9NQF0; -.
DR STRING; 1291518.A0A0D9NQF0; -.
DR Proteomes; UP000054544; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:InterPro.
DR InterPro; IPR004294; Carotenoid_Oase.
DR PANTHER; PTHR10543; BETA-CAROTENE DIOXYGENASE; 1.
DR PANTHER; PTHR10543:SF24; CAROTENOID ISOMEROOXYGENASE; 1.
DR Pfam; PF03055; RPE65; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|PIRSR:PIRSR604294-1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723,
KW ECO:0000256|PIRSR:PIRSR604294-1};
KW Reference proteome {ECO:0000313|Proteomes:UP000054544}.
FT BINDING 235
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 287
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 357
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
FT BINDING 567
FT /ligand="Fe cation"
FT /ligand_id="ChEBI:CHEBI:24875"
FT /ligand_note="catalytic"
FT /evidence="ECO:0000256|PIRSR:PIRSR604294-1"
SQ SEQUENCE 580 AA; 64200 MW; C4367487A2AAF4EC CRC64;
MSAAMNDPSV IRRTAADEEA DAKEALQNFE NQRWISWPNE GAFDALDEQY DSVHLKVKGS
IPSWAAGSLF RTGPGQSMVE NTSRGTHHVS HWFDGFAHTH RFDIIPPPAG DSATSVVYSS
RGQSEEYITM VKKHGWQTSV SFGQRSDPCV GIFAKFMSIF LPQKVNNNVA VIANMPGLDS
SGGRRVGHRT GLDNVYITTD NSTLEKIDPE TLEPLESAAQ QQLHPKLKGP LSCAHAQKDP
VTGDLFNFNI DLGRKATYRI FRVNADSGTT DILATIAENE LPAAYIHSFF LTENCVVLCV
PTSHFGWNGL KILWERNVID AIQPFDKSVK CKWFAVDRRH GRGVVARFST PASFFFHSVN
AFEQKSKGSN GEEITNIFLD MVEYVNTDVM HMLYYDILMN RNQDAIKDLR KRDKYKTSQP
KLVRYKFALP ALSQTHMGDY SLAADQVFAI LSPHAGELPI INPSRSGKAH RYVYGTCNRG
VGFWMDGIVK TDVETRDALI WSGPVGHTPG EPIFVPRPGG TDEDDGVILT VVLDGSAQTS
YLLCLDAKTL QELGRAETDF PIPIGLHGIH TPLGEPSVPS
//
