ID A0A0D9P7R0_METAN Unreviewed; 1124 AA.
AC A0A0D9P7R0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=VASt domain-containing protein {ECO:0000259|PROSITE:PS51778};
GN ORFNames=H634G_04009 {ECO:0000313|EMBL:KJK80860.1};
OS Metarhizium anisopliae BRIP 53293.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=1291518 {ECO:0000313|EMBL:KJK80860.1, ECO:0000313|Proteomes:UP000054544};
RN [1] {ECO:0000313|Proteomes:UP000054544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRIP 53293 {ECO:0000313|Proteomes:UP000054544};
RX PubMed=25102932; DOI=10.1186/1471-2164-15-660;
RA Pattemore J.A., Hane J.K., Williams A.H., Wilson B.A., Stodart B.J.,
RA Ash G.J.;
RT "The genome sequence of the biocontrol fungus Metarhizium anisopliae and
RT comparative genomics of Metarhizium species.";
RL BMC Genomics 15:660-660(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the YSP2 family.
CC {ECO:0000256|ARBA:ARBA00006582}.
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DR EMBL; KE384728; KJK80860.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D9P7R0; -.
DR STRING; 1291518.A0A0D9P7R0; -.
DR Proteomes; UP000054544; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR CDD; cd13220; PH-GRAM_GRAMDC; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR004182; GRAM.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR031968; VASt.
DR PANTHER; PTHR23319:SF4; AT22714P-RELATED; 1.
DR PANTHER; PTHR23319; UNCHARACTERIZED; 1.
DR Pfam; PF02893; GRAM; 1.
DR Pfam; PF16016; VASt; 1.
DR SMART; SM00568; GRAM; 1.
DR PROSITE; PS51778; VAST; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00022989};
KW Reference proteome {ECO:0000313|Proteomes:UP000054544};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT DOMAIN 765..936
FT /note="VASt"
FT /evidence="ECO:0000259|PROSITE:PS51778"
FT REGION 1..114
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 133..305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 325..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 641..760
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1071..1093
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 30..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..84
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 133..162
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..223
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 228..246
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 286..305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 325..361
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..380
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 383..398
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 415..472
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 669..698
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1124 AA; 120703 MW; A4ECF45A12209BB8 CRC64;
MDGTAASSGG LRVGKLLPKG LSAKRRRRKD KNGRDSEASG ADDDTRSTSA HSSQRRFKRE
LTLESDDANS TNIADDDDDE MDDRSFGSFE SGADPETADR GRPASSSAPA RPATISAHPS
LIGYLTTSSP VVQTQHLDSR SHFLSSSQAR GYSSGSSDKS LSPEKPSKAK GVPGFQNSIP
EPPAPAKIAS ADRKGRASTP KIETNPPRTP PQDDKPAPVI VNTPPTPTDR ADHPQFATSP
DGRSSTNGAD PKLRADGSAA ASNMNIHRRS KSGSAAIGPS KLSHITAAPL TPTDETGGET
TQSATGFFSS MISAAQNAAT SISNTIPSTG LGIGSNKNRT GTPKSLNSPA ASQTTLNSQP
APEPEPRIED TMDRKESAVR TLGSGDLSLS QLGLPESSIT SPAGARFADV ADTRTRSESA
PTEPQTSATD VLPAESSSRP RSLAEPASGD QTPPQTDLSD LKGPVQRSSS LRSAMKPHRK
RGSSATTGGT IAAAITSTTN AALPSSGGVG APKLTGFAIA SKKRNRDFHN LFKSVPDDDY
LIEDYSCALQ REILAHGRLY VSEGHLCFSS NILGWTTTLV MSFDEIVSVE KRSTALVFKN
GLMISTLHAK HIFASFTSRD ATYDLIVNIW KLGHPTLRST LNGVQLEGTG GDKTEKVEDQ
QGAVEEEPQE ASGSEEDTDD DEGDDEEFYD EEEHDEVLET QSTDMTAVEP DPERPATRKV
SGMTAVNGVA SEPSKDASPP PGGAPDFPGP SAHAPTDCGD STAHYEKVLG DEIIPAPLGK
VYNLVFGPGS VTWMNKWLST EQKCTDIQME DKKGLTADNK SRTFTYIKPL NGSIGPKQTK
CVVTETIDQM DLEKAVNLSV STQNPDVPYG NLFTVKTKYC LSWAENNATR IQINCTVDWS
GKCWLKGTIE KNVNDGQGQY CKELFASLKS AVSSRARSGT ATNGIVKGKK KLKRSKALQA
VVDLEASKGG KSDGGKQNWG PLEPVRSILE PCVDVLQPIL TGNVMYGLLV GLLVAMWFGF
GSPPKNNAPF GADVGFYSHN RQAAYEEMWR RQDSELWEWL EERVGMERLS SDQPSARKRG
MEHRTVEDKL REERMDEREI QEAIRVTEEK LRVLREVIGK GRPN
//
