ID A0A0D9PBN8_METAN Unreviewed; 1068 AA.
AC A0A0D9PBN8;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 22-FEB-2023, entry version 28.
DE SubName: Full=Exportin {ECO:0000313|EMBL:KJK82220.1};
GN ORFNames=H634G_02414 {ECO:0000313|EMBL:KJK82220.1};
OS Metarhizium anisopliae BRIP 53293.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Metarhizium.
OX NCBI_TaxID=1291518 {ECO:0000313|EMBL:KJK82220.1, ECO:0000313|Proteomes:UP000054544};
RN [1] {ECO:0000313|Proteomes:UP000054544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=BRIP 53293 {ECO:0000313|Proteomes:UP000054544};
RX PubMed=25102932; DOI=10.1186/1471-2164-15-660;
RA Pattemore J.A., Hane J.K., Williams A.H., Wilson B.A., Stodart B.J.,
RA Ash G.J.;
RT "The genome sequence of the biocontrol fungus Metarhizium anisopliae and
RT comparative genomics of Metarhizium species.";
RL BMC Genomics 15:660-660(2014).
CC -!- FUNCTION: tRNA nucleus export receptor which facilitates tRNA
CC translocation across the nuclear pore complex. Involved in pre-tRNA
CC splicing, probably by affecting the interaction of pre-tRNA with
CC splicing endonuclease. {ECO:0000256|ARBA:ARBA00025147}.
CC -!- SIMILARITY: Belongs to the exportin family.
CC {ECO:0000256|ARBA:ARBA00009466}.
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DR EMBL; KE384724; KJK82220.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A0D9PBN8; -.
DR STRING; 1291518.A0A0D9PBN8; -.
DR Proteomes; UP000054544; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR041123; CRM1_repeat.
DR InterPro; IPR041235; Exp1_repeat_2.
DR InterPro; IPR013598; Exportin-1/Importin-b-like.
DR InterPro; IPR001494; Importin-beta_N.
DR InterPro; IPR045065; XPO1/5.
DR InterPro; IPR014877; XPO1_C_dom.
DR InterPro; IPR040485; XPO1_repeat_3.
DR PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR Pfam; PF08767; CRM1_C; 1.
DR Pfam; PF18777; CRM1_repeat; 1.
DR Pfam; PF18784; CRM1_repeat_2; 1.
DR Pfam; PF18787; CRM1_repeat_3; 1.
DR Pfam; PF03810; IBN_N; 1.
DR Pfam; PF08389; Xpo1; 1.
DR SMART; SM01102; CRM1_C; 1.
DR SMART; SM00913; IBN_N; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000054544};
KW Transport {ECO:0000256|ARBA:ARBA00022448};
KW tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT DOMAIN 26..92
FT /note="Importin N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS50166"
FT REGION 1043..1068
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1043..1062
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1068 AA; 122301 MW; C3AB9EDA48C7D5FC CRC64;
MAVTIEELDT TVRTFYEGRG DQQKAAQAAL NQFKEDPDAW LMVDKILSTA QYPQTKYLGL
QVLDNVIMTR WKVLPRDQCQ GIRNFIVQFI IQCSSSEDAL KSNKTLLNKL NLVLISVLKQ
EWPHNWPTFI NEIISSCHAN LSICENNMII LRLLSEEVFD YSAEQMTSTK TRNLKQTMCA
EFSQIFQLCQ EVLTTADQPS LVHATLETLL RFCNWIPLGY IFETSLIETL RTRFLSVPEF
RNITLQCLTE IGGLQTGGAG QSNSYDEQLV KMFTEVLTTI ADIIPVSLDL KATYPTSNSR
DQEFVQNLAL FLCNFFGTHL NLIENLPNRD YLMHGHYYLI RISQIDDREI FKICLDYWLK
LVQELYEEMQ QLPITDLNPL MAVGGMSGSG APNPTLLMNY PLRKHKYNEV LSNLRVVMIE
RMVRPEEVLI VENDEGEIVR EFVKESDTVQ LYKTIRECLV YLTHLDVVDT ENIMTEKLAR
QVDGSEWSWH NCNVLCWAIG SISLAMNEET EKRFLVTVIK DLLGLTEMKR GKDNKAVVAS
NIMYIVGQYP RFLKAHWKFL KTVVNKLFEF MHESHEGVQD MACDTFIKIA RQCRRHFVAL
QPSEQEPFIE EIVRNMGKIT CDLTPQQVHT FYEACGYMVA AQGNKHQQER LLADLMNIPN
AAWDEIIKQA TVNPSILQDA ETIKVIGNIM KTNVSACSSI GPYFYPQIGR IYHDMLEMYR
ATSGELATKM PRVRGLRTIK KEILKLVEIY VEKAEDLQAV RAQMVPPLLD CVLVDYNRNV
AGARDAEVLK AMSTIITKLS ALMEDQVPTI MENVFECTLE MINKDFSEFP EHRVEFFNLL
RAINLHCFPA LLKLDNNQFK FVIDSCSWAF KHDNRDVEAA GLNMCLELIN NIAEKTDVAT
ANAFFQRFFM TILQDVLFVV TDNDHKAGFK TQSMLLMKLF YYIHPADGTQ PKIQGPIYTP
DQAQAGTSNK EYLGNSVAAL LRNAFPNLQA AQVTSFVEGL FSFNTTYDKF RLNLRDFLIS
LKEFAGDNAE LFVVEKEQRE ADAKAADMER RQKVGGLLKP SELEDEEL
//
