ID A0A0D9QE71_PLAFR Unreviewed; 636 AA.
AC A0A0D9QE71;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=NLE domain-containing protein {ECO:0000259|Pfam:PF08154};
GN ORFNames=AK88_05266 {ECO:0000313|EMBL:KJP85097.1};
OS Plasmodium fragile.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5857 {ECO:0000313|EMBL:KJP85097.1, ECO:0000313|Proteomes:UP000054561};
RN [1] {ECO:0000313|EMBL:KJP85097.1, ECO:0000313|Proteomes:UP000054561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=nilgiri {ECO:0000313|Proteomes:UP000054561};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Duraisingh M., Young S.K., Zeng Q., Gargeya S., Abouelleil A.,
RA Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium fragile nilgiri.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ001751; KJP85097.1; -; Genomic_DNA.
DR RefSeq; XP_012338291.1; XM_012482868.1.
DR AlphaFoldDB; A0A0D9QE71; -.
DR EnsemblProtists; KJP85097; KJP85097; AK88_05266.
DR GeneID; 24270580; -.
DR VEuPathDB; PlasmoDB:AK88_05266; -.
DR OMA; AWEPYHR; -.
DR OrthoDB; 859at2759; -.
DR Proteomes; UP000054561; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR CDD; cd00200; WD40; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 4.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR012972; NLE.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR19848:SF0; NOTCHLESS PROTEIN HOMOLOG 1; 1.
DR PANTHER; PTHR19848; WD40 REPEAT PROTEIN; 1.
DR Pfam; PF08154; NLE; 1.
DR Pfam; PF00400; WD40; 6.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 8.
DR SUPFAM; SSF50978; WD40 repeat-like; 2.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 6.
DR PROSITE; PS50294; WD_REPEATS_REGION; 6.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT DOMAIN 15..85
FT /note="NLE"
FT /evidence="ECO:0000259|Pfam:PF08154"
FT REPEAT 118..159
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 160..201
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 338..382
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 465..506
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 507..541
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 603..636
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 225..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 551..593
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 227..259
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 556..573
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 574..591
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 636 AA; 71281 MW; EC4DB3DA5F17965D CRC64;
MEEEDGGNDG LNKQILIQFV NHENKSTGPV INVPLSITKD NLDQLINDLN TKNDNSVEDD
YEQNINYSFM VNDKLALKNN LYDTIKNNNI SREDILRIKY FPLNIFKIKR ITTCNSTLPG
HTNSILCLAF SPNSSHLATG AGDNTVRLWD INTKTPIVTL KDHTNWVLSV LFSPDNKFLA
TAGMDQNVFI YETHTGKLVN KLSGHKKEVT TLCFEPLHLL NKNSIQKNTH EVRKRKKDNE
TEKEDTRNGA KRGKSDAETE LGTASDGPPN GYSQVIENGT KMANESNVTA DQYETNNDNI
GGAPHKSTYF LKCRLATAGK DGCIRISNVM NNCVEKVLTG HTNTITCILW SGTDQENSRI
YSSSRDTTIK VWNPNDGTLI HNFKGHKHWV NCLSINTERI IKNGIYNLDV IINKIHIENH
IEKSKKIFNN FFHTVKNEKL VSGSDDGTLY LIECLPNDEF KPTRLIGHQK TVIHAQFSPD
GKFIASCSFD NTVRVWSSSD GQFLTVYRGH VGPVYKVVWS IDNNYVVSCS QDSTLKLWKV
SHLLAQLKNK KVTPSGEEDS TASTNGTSKH QQGNSDPSEK KKNDKDCPNG KNNKKVQTLL
VDLPGHSDAV YAIDWSNDGK FVASGGKDKL LKIWSY
//
