ID A0A0D9QJJ0_PLAFR Unreviewed; 2752 AA.
AC A0A0D9QJJ0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=FH2 domain-containing protein {ECO:0000259|PROSITE:PS51444};
GN ORFNames=AK88_03142 {ECO:0000313|EMBL:KJP87225.1};
OS Plasmodium fragile.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5857 {ECO:0000313|EMBL:KJP87225.1, ECO:0000313|Proteomes:UP000054561};
RN [1] {ECO:0000313|EMBL:KJP87225.1, ECO:0000313|Proteomes:UP000054561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=nilgiri {ECO:0000313|Proteomes:UP000054561};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Duraisingh M., Young S.K., Zeng Q., Gargeya S., Abouelleil A.,
RA Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium fragile nilgiri.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ001678; KJP87225.1; -; Genomic_DNA.
DR RefSeq; XP_012336187.1; XM_012480764.1.
DR EnsemblProtists; KJP87225; KJP87225; AK88_03142.
DR GeneID; 24268456; -.
DR VEuPathDB; PlasmoDB:AK88_03142; -.
DR OMA; KDHHFWI; -.
DR OrthoDB; 231882at2759; -.
DR Proteomes; UP000054561; Unassembled WGS sequence.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR PANTHER; PTHR45725:SF1; DELPHILIN; 1.
DR PANTHER; PTHR45725; FORMIN HOMOLOGY 2 FAMILY MEMBER; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51444; FH2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}.
FT DOMAIN 2099..2502
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..141
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..512
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 693..806
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 933..976
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 989..1008
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1259..1300
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1318..1394
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1657..1713
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1738..1761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1946..1973
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2012..2072
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2647..2681
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 2417..2444
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 114..129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..475
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 478..512
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 742..777
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1267..1300
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1335..1383
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1678..1713
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2033..2055
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2752 AA; 314571 MW; 8F8C751B886BA092 CRC64;
MRNHLEKNAK GTTEKKHQRR NTNEKEKEEE ERGYGMNTIY HQRVGKMEAI RIDSFCRKKR
VPKETLWNIE NSQEDDENMI CFKNFVQNDL SDDNVNGRGD IVFDHFGNAQ RRNSRWDIRS
QSGSRNESWN GSEKRSKVRR KSMRDKLIIF NNKGQSRNPP RDHKHNSITG LNLTNYMMVP
DDIRHKYTKT YLFQISKRLL VMKKPWRLPK NVELQINNVY HLSNYIKVLE RISNEYLNDP
PINYYYKGLE LYNKNVFANI DYLLKKVDIK KNPKNFQYRN LIKVNECYYD LSTFGKSPSA
MLYQSYVIWD VHGSSLTLEQ EYENFFNSQI MDYSFGEKEY PSLKYILSIC SSILFWLNFN
KKDNFAIINY HKISSFILLI FSCVMLVIDN TLTFSQIQEI LYKSSKISNS DKEDVEDSVD
TNISSNYFGN KYDTVSNEEE SDDTYNLLAR GEAESGGHSR ISLDNRMTNL QRDKYEGSGS
IYDNEEDSDP RSKNYKDKSL ENDSYTKKRE TSDSLDDIYH FGNCNSEDYP TTYDNHFKGG
NITFTRNGYK SSKPVSNLSK MQYHTLNLNG RKSVEYDNEM DSSQKKKKTK FSNSWGFDLT
NRENYRSSNK VKDHHFWIPF DYWKSSHKRY FFYIYELMKN KNKKVENVPF KLKSIIFSDY
VMCSVSVEVY EIIYKDNQEF HLDVLSDCGY DTAGAEASTG EGTSEDQSES VEPSGERSGK
QGAKGSKKKH SGNQRHYQCN NPKECTEVDE SNEDYTRNEE PKGEGLPEDE SFHRNSSVER
NLKSGTPNGR DSNAPLKGRG SSDYSDEIIH HRASVKKGNG NIYGMYKKPG GRKLSEDNIP
YDESDTPSGL IVPKGDLTAN SIFIGRNYEP TACVRNKLKK TSSCYRLRNG SNGFRDSCEE
ASLNTTNRSH LSNSANSFSG SNYERSLQGK LGEADGRGTN SHRFHVRSGK GPITHKIRQH
GGKYYSPRSL SSVSPEPTSI DHVYSYKNEG IPDSDNIQRG RSKGKITTNA QVKRKSCTFF
PQKKVSSSEE LHEPLSSVMN KPTCDVSNVG EAEHKKDSTW KEKKIYEFLR KNRKRNQKKG
EDRNKGVSSE KSGYEYFLKC NNLSYNIVSS YEKNKKKYVT IDFTHDPEGN TKEHIICGDV
LILIGHKNIE KFHKGFSSSY SFHTGFLKKA SSEILHIRKE DMDINSNYQS YIPDGMKLSI
ILDSANRSDC MKAYKRNLRG HNKMEDLKSL KIFEKNKSFE SIDSERAVYD LQASITAISA
PDGGRHNRGE TGVRDKGRRR TKGEREDDSN EEEEEGKSRW WKERSAHNVV NCRRERMATV
DDDEEEDDDD EECIEQRCEQ HSDKEHEPNG PSHHMGETRQ TSQKRRERVR YTSPEHRDPR
NKSNCSNSKQ MDSHSKINYS GYSIFNKKEP KIKYNATNIT QLLTSLFGFK NREDKYSLTN
KQSVCSLLSS KRSFSNLISL KDFLQRQYEV ITNPTESMYN FVKNHVLKVN IPLVQYLKKI
THLSNLKIYF SLKLCNNDLS KSLNFIVSIW GIKILKKKSS IRYSSTLNEL PEFREEFKEI
VPHDVDIKTP TEIARHVNDV DSTNVSCTHV DVYEKLEDSA NLFKEHEQVP AGKDAEVVLS
KEPCRKVSSL HRLEETFEWT KDPGDVLHLK ELHPYRESEA VSSTSVARGE ETSEVKIGTQ
KEVTPSEPNE VSDQNKLKEP STQKMQNEGP SEVITNIDGI KIAKMEINKT YYQMREETNF
AKSKEEPDLR KNEKEMVQEH PKKTIEDNES FLNSMMEKDE PSKGIEQTNT KNDILKKIEG
NDFFYGKLPS GELVKIKVND TNELGTYDSM PLLLIEPVDD SGHLKRAMSG LSVKEESDKN
ENATLEKAAN TDCLVNDLEK MYDQKVIKKS SIESTLSVES DRSTMSRYST SLVVPPPASI
SKGELPAGKN VEVKIDQKID AKINQQVDPK VEQKADTKVD EKMDPKVEQK ADTKVDPGVV
VKPPALATKQ MTKQPATEGQ TKAKAVEAIL RKAKEKRPPP PLPSALQKRP PAKATTEGKE
PGGDTKKESS VKPGVPKKMG KKMPGPPPKP PFALGKGIMG EKTKMGMKKC PMNFAPKKFV
KVQEKRPLGI KLHWQLLPTH KIEGTVFNEI KTQEAKYTLI DTKAVHKLFA RVKAEKKIVK
KSTEEKKKSN EEKLITVLDR TRAQNIGILL RFPMSTQEIV QKISVFDLEN MSTEFLQKVL
HILPTKEESD SILQKLEHEN VKEEHFRDVE RKLIPFVYMD KCQCKIEICL FSLKYEKMIN
EINKDLDVYD EAVKEVRSSI RLRSLLKAVL KWGNYVNYGV NDNEDLVALG FTLSSVLKLT
EFKSSIDNTI TSLHYITVSL CTYLPNLNMN LLENDLNSVS VASKMSSETV DILLASIDKD
INYIGEQLKC TYEEVFKEKM KSILQDSEMK YANAQKRYEE TKKSVQQLGT YLGEDMSKSP
NLEGIFIVLS SIVDNFTKCY KDILANPKKF SIMLNDENLL DEYYTFFGKK KNKNLPSSKN
CTPISKEAVT KEQGATKESE KITGKIRINR LNSCMGVVRK NDNAKSSMFQ LRTKLMQDIQ
NRAFIKVGNS DGDKVKCEPT IPLCNQKDTP IPNIALGKND MRVESAQGLS ENGNCVDTKG
ATVPHGCVLG GESKSRKNSA GSVNETRLEP KKPIGSVNET RLGVDNSLGS VNNKTRLREG
LNCDEKPNGD MAAEVKLTES PKIESKPNVS TKIEDKINDE ISGLVAEEKI VE
//
