ID A0A0D9QQE0_PLAFR Unreviewed; 5361 AA.
AC A0A0D9QQE0;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Zinc finger PHD-type domain-containing protein {ECO:0000259|SMART:SM00249};
GN ORFNames=AK88_01309 {ECO:0000313|EMBL:KJP89017.1};
OS Plasmodium fragile.
OC Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida;
OC Plasmodiidae; Plasmodium; Plasmodium (Plasmodium).
OX NCBI_TaxID=5857 {ECO:0000313|EMBL:KJP89017.1, ECO:0000313|Proteomes:UP000054561};
RN [1] {ECO:0000313|EMBL:KJP89017.1, ECO:0000313|Proteomes:UP000054561}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=nilgiri {ECO:0000313|Proteomes:UP000054561};
RG The Broad Institute Genomics Platform;
RG The Broad Institute Genome Sequencing Center for Infectious Disease;
RA Neafsey D., Duraisingh M., Young S.K., Zeng Q., Gargeya S., Abouelleil A.,
RA Alvarado L., Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A.,
RA Gujja S., Hansen M., Howarth C., Imamovic A., Larimer J., Pearson M.,
RA Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S., Wortman J.,
RA Nusbaum C., Birren B.;
RT "The Genome Sequence of Plasmodium fragile nilgiri.";
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ001655; KJP89017.1; -; Genomic_DNA.
DR RefSeq; XP_012334368.1; XM_012478945.1.
DR EnsemblProtists; KJP89017; KJP89017; AK88_01309.
DR GeneID; 24266623; -.
DR VEuPathDB; PlasmoDB:AK88_01309; -.
DR OMA; VNCILCS; -.
DR OrthoDB; 248869at2759; -.
DR Proteomes; UP000054561; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR001965; Znf_PHD.
DR PANTHER; PTHR13793:SF132; PHD FINGER PROTEIN RHINOCEROS; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF13771; zf-HC5HC2H; 1.
DR SMART; SM00249; PHD; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT TRANSMEM 456..479
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 3638..3704
FT /note="Zinc finger PHD-type"
FT /evidence="ECO:0000259|SMART:SM00249"
FT DOMAIN 4116..4184
FT /note="Zinc finger PHD-type"
FT /evidence="ECO:0000259|SMART:SM00249"
FT DOMAIN 5002..5074
FT /note="Zinc finger PHD-type"
FT /evidence="ECO:0000259|SMART:SM00249"
FT REGION 932..1063
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1195..1214
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1330..1455
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1782..1817
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1854..1877
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2013..2034
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2135..2156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2325..2378
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2636..2658
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2684..2734
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2953..3000
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3152..3192
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3219..3250
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3471..3499
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3560..3631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3804..3883
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3901..4027
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 4471..4504
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 5122..5361
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 4359..4386
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 955..979
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1330..1355
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1362..1378
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1395..1455
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1782..1802
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1854..1873
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2017..2034
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2343..2373
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2720..2734
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2953..2968
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3153..3192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3232..3247
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3560..3580
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3581..3603
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3605..3631
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3808..3840
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3845..3865
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3924..3956
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3993..4027
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5131..5151
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5159..5182
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5241..5269
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 5282..5305
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 5361 AA; 592878 MW; 8DDF9E90DC9EAD88 CRC64;
MSSVQGSSVH TVLCRNKMKV VFDHGVTCGG VIKGTTQMDK TQNAEWDVQN YACHVPVKNG
PCFGHNAKVF LLVMRHLYKT HDHQDAIHGA MKKTNFFSNM KCAVLLLLVL YKNRKKASLV
AHLAVNSGSP RGVLSHGEHT YNTGAACGHD GAEQAAERGS DGDDETGIYL DVHSTGRTAS
PPTPKKNILF LKRSGHSAMF PFCKNVNCVK VKKKKGYHNR FKRKGNVHAN FHRTSSFKWS
CRSPNASDLT ESEQLLHSAH LHPLAETKNC SMRRITIVKT SLANVHLPTR RSIPSTSVNH
KKTSNKCKVS SLWRSRDLRC ARHACQGNKG IIRSCTPINV LNDCKDNETK VLCPHMNSNN
ISEAAYNTND GVILSRYSLF HVNGYDPQIT PKCEALIFKA KECRNVVGNK KIFVTVGKGH
MINSCGKANW CRGESRLEKT PLLYLHMINW VAANRVAIMG LIAEGIFCDV ITLLFQVTII
TVARMAAVMG VIVFSVAIAL SEILIYTQLC AHMMASLLEK RPPLIIRQSK CSEATTPSQR
CMSTHKCNIY NLSLKHCTTG PVTSSHSTRA LISFSSSTLS KKECDIWKVG CPSVESSPSC
NLQAAENKSL LAVHVGGEHH GGLNITAVDI PRDRIKQPAC IFCPPCNATN EFWKRHQCLM
FAACLPIVHV CDRSENRKSR HRPSGHAALP FFPLMTSSSD YFCPYSNEAI NATRTCFTYR
LCFVCIPLRE FSSCYEFHHV LIFHNAQLFK GVCLMLAELI IALFFVIHVM SVRLCTSMIA
ILNEEGDARL SMFFLNKKAS TRVLTCVVSS RFIHLLDKYF KAHLRASLIF YLNGAGTFGR
KNDTKNCSNK DCDYATTELF RCLYYYAPMM IARFLFNSGM SNTFCVSSDE DEISENTDTP
TLLSIVGKPR TGHNHLWKYN LGRGDPHVCS NPVGDSEWGG NNNDGADGGD CPTAGNSNEG
GNHPQEVNNN LNGNGNQGGD TGDKDDRDGN DNNEDQGGGF PEGEEQDENV LMDAQNGKTK
KKRKKTLNDK SRNINKATTG RKSRTKTDTP NDKQDENNMA AGNYGSVHNM KQLHKFGGMN
SVAGVNNMGS MHNGSFLYNN QVSDKIMHDG MGKMTMKSGG GYPSRMGGDA NFQMGGHVGG
HVGAHSGGHA VGQMHNGNMN MYLNNTGSMQ YMPPYANSNN PVGMSLSSGV AGSANGSLGN
HANSSGQGSS SMHGQMKHLN SGFRNSVMKN NSSQMSRMMI SPLSPQLAHS GVNSGVHSAV
NSGAGNNMGN YGMHFNQQQG SIANGHVGNK VSYHMNGQTG VGCAVQSGMS NAGSNSFVHH
PNNHIGSVPN SLSSSVSSSA NMHMEDSNAS GSNHKGHMNV HPRGNTRSTC SMSSQLGGLQ
GGKPGAHING PMHSAGSGHM SNQMGAHAMS QTSGPLMSQT SGPLMSQTSG PLMSQTSGPL
MSQTSGPLMS QTSGSLMSQT SAHSNKVLTN AISMNKLNNS KNTKSGNASL SMNSHMMNPM
ASYMGPNMGS NMGRNSVTKN ITGNTQDGMN NGKMQDTVMN SSVYRSNSLL RDTLMGSNKA
GPGGAMQNQM MKNAMMKNEM RNNSTYMVGM VNDNLVHTNM GMGVRGSFRP MNSLPVYNNG
TAMKFAGQRY SMSTMVPNST GPTAAAAAAA GGMMMMNREM NEMGSTPGMM NYISGNNFIN
KNMKGVKMEH TYPFEQMNMR NDQLHHVEVH QTNMGHMSVN NSKMYLSNVQ VGNDKISGGN
FLQGESNQFY SYGSGPNDTC GGTVHKSDMN GVANANVCGT TKDVGSVSSN KQNTVLNSKK
KSKNNLKNGR EHEMNNSQNL RTVKINWSKY DSIFKKIKLE KDYEKFINTD KEDAEKKRKN
NMSDADTDDK SDWEQNPAPG FNDLLNINFR SFIHDYNEIL NKLNSIRVND KSEFKKNAYT
QLYEEIFLNI ERFFDISQLR HENNFTHSNF YKNTLDRVSE GDMLLANGSG SDGYEGAGVT
STEVAVVNQN AASASVGNLA HKTGKAKVNR GVKSQCTDPE KGTHTHDGED DIMNKGKTNF
FQSVSRSAGN NSLFEMLLKK KKEFDEICML HNFDSAMANG EVAFPNDTSG RNVTPMDRSL
ASVEKKFTSS SFQGSPAKNK MGTSVPDYKT GVTHVGSGNV RYPHENNPGT NKKGGSEIKN
AAYQNHFIEK ILSKRYRTYS INEFVNVQLN DNLLELIDMY KQNLCFNIRK MLKKKISHER
KGRFDWHYGV KRVSRIGRKT RTGKRRELLT GRGKKKKKKI MGKGKEFPST TLKMMGMINS
SDELACAEAA RSTHLGDHHP VTEGKNASGE NLEKPLFFFS SGNFRKRKKN DQDGSANVGD
GIGTEEGERR NVEELSPGRK CEEEQRKDGG GGDANDNVDA GINKFVNKLS FGLFQTKLKS
PQKNEGEMKN RSDSTVDHCT MENHGDISLY IEKNVTQKKS PRTSAAFMLA SKMECTNLSI
SRMQKRLFDE RRKIKLNKQR KMRNLKYKTN AIIDFGDKIV WVSFEFNHLD TLRKIKNNFF
NLYNLSQLEK TKDSDINLEK CITNEMKKYK NVKIRFYKFL SYYDFVFLKN RLNFIKIKYK
NGVARTARGM TFPGTSLAKL ADMQRDHPAE ITSVKMPAGG AIVSDPTVGN VKCEAVQNRD
KDDSSPQDGP SVEQAKSGAV LSDVHPGAEL VKKDHPQTGA LFSEKGIIKG GEVNSGNNNP
VLKSEGGEEA QHHDQQEPLT KEQLPTPLHN SPSIIVKSEH PKSEVIYPYL PFAKTRGDDI
NQILNDVKNL YIEPNDHMIK KNKLRKDITL FPLIDKKRLN TYISLDLNAA AKEELVKNEH
TNNHSVDKEI HILNKFLSTN LKLEKMEFGK VGSGINTSGG GAATTGAATG GGAVGPGIII
ENYDHARNNH MHCEKYNTAN SVLIDNYVWS NNPSLFSIFE KYYLLLKMQK YILQYKHFSK
NSLKRKLSSE SNCDVYSSSN SLKGSSSGNV KGRRRYGKGG KGTKKGGGGR RLSSSKGGRR
GVAAMMASAN DGMAVDTVGV KRRRKAAVVT TSQPCKDVSD QVGFAKNDMN EHGLVSGETN
EHLAATPFVK VEPEGASTCV DSIQNEGGGE VQGMSAQRYN TPIGGTGTNG SVEVPPEQID
ALYPAMKNKV EEEANAMGRS GVSDEVQVAN GEAVPQDANT INEQSVRRTC KSESNSSGSV
KSAKRNKSSL QTNVAKGEMN FIGVVKDGDA VGDSDAEAEF DTELEDGSGK KRRGRKKGKK
RGRKKGGRNK YKLEEDNMTV AESNRTMWKK QNGEYEKYQL KDSKKFTDLI NNEDMLDEMD
KEILANEVIP IDKDIIIDLL CEEEKLIESY IKNSKFVDKN LICFLIYLNT VQKRLSCISN
KLLKKVIREN KMPARISENV SRSDEITYRY LMFERWNQLR YSVFYNMNYV RSGGSRVMLH
DSAQSDGYKN VNIQTIFDLH KFSGKYKKQK LPPFEYSMFL KYKIHKQSKT CASGQEGGER
GGECSPGGEH TEGVEEMEDE ETVFMNNEDN FCGFSNNTDL NITPVLSYCC VCFNDDYNTT
QISEQGDPVQ NVSRNNSISN SAVDVKSESM DKTQQGQGRS RSNSKRDEVG ASGELKKDGD
QKGAQEATQP PQEGTLRSMG GSQINNPSGE CEKKINSTCS GTDTAIIEKN IKSNRNLMMR
CGRCYMHVHK FCYISTKRTE ESSSTYAQAT TSISSNEWLC QRCEFEKKTL GNNYLYLFDN
HVKCYICIER GGAFIQLRSD IFVHTFCAMF CVPDLLVNAN VNLENVEEFL KLNNVSLTQE
ILSSLERKRR KLLLSGDRAK KGLAQDGLPS VTGNSNLMDP CTESSPHPSA VNSPVSNNPA
HVAKGSDEKT ADCVNLEKNE EAKGNTASGE ADGGGDPNPE ADTEYGFRIK SIRSIFSKSY
FSSPKHSDKK NAHATSGNDK VGDFPPSEQK EDKKKRGSEN VSQVENLKKK KKTAGSVNDE
VNTLHSDKGG TNDTLETDGD VAKGSAAPGE DKGKGNNRAH RVEQGDDGMR SGFDHSKDTD
LAHGKQDGVR IQCGERYLHD GYSSSESSSS ILTASSIRSD STLLPQHDAK KAEEGDHDGE
ATLHRAGTTQ KEKNIPTKQL SCIRYLLNGY GQDTVRCDVC LKSKGIFIKC ENIKCDKYVH
PLCAYMCGLY IRCKNSNKKF LKFQNKIDYC FPRIFFFIKC ISHSIKKCGV IRIYEEIIKR
RTKYLNRDLY PSIYESNKKE RKQKNSVKYK IKNNCSNIKK GGSMAGGVGN GPAAIAAIAA
VAAGGPGGGT GDIYEVLAFN FNYLDSYQYN FFLLPSIDYI KNDICLVCFT SYKKKELLYC
KYCNMCVHKS CYLVDSTYLE YHFYRKNKRA HTFLMHTKQQ KLKNLLSRVK ERKEALLNAL
LQENNQHAYD DVSQGGVTGI VKEDGTTCGE IIPRHGMIDL PPQEGTSSGD PCGVKGVHVE
EQLLEMHNHP SVEKSHVDIP PVSNHIIAPE GGEPNCAEQS GVAPPGEGSA GHWQQHPHNG
KGMNREKEME KSKLFKELMQ NEVITCLYTP EYLQSTDFIN KLKEFKKKQN VMQLSENVKY
KCEEEKCLTD LDDVEERKLF VCDLCANNYN HENVNCILCS RRGGAIKLIK VNDHNKVDKN
KNKKNAFLKS EKDFVFVHMQ CALYAPQIII QDIGEEYYQM FNYDNYSMQE CDEVSQMKDK
GFKSDTEVCV LNKECDYDEK QNLLGEFLYR HAAAPTVNNN KGKNARRVLD RKNSATSACV
AANVVVGGAV AVASTIHATP AQHTLAQQGV AVEVVAAAGG SIQIKEETNA AGGLVGKVVP
PVSCNVRQPN EIGKLAEGEG DAKVKKSLSF DIEKGGADGA MALTENGLQN TALNAEQCGE
RLVKEEGAHP TEANNLMSIA QQCPNGTTNN NAILNETSNT AAIPNTILNV TDNSAASNNA
ILNVRDKYGR RLKKGKEILS YNKSNSMMGG DPKKRQIVPS STHVPFSNKK TSNLYYYNFN
RKKNNYKIII KDKLKKHLNK NVCYICNLTY GYTQKCVENN CNNYFHISCA KIHKHFFEFD
YTFLKIFPNV MSMQQMSKLS SCSVGTIIFC EAHSRIRRKV NPSIKLFSKL RSFLELARII
VGQMKKREDI KNAWIKEKHQ RDITSFEHTE EDVDNPDEGQ DPEEVDDVDS SISMSDSDGA
EDGGDDDSDE EDDDDFSEEE EEGSMMSGSA RGVSRNVLYA PQTDGEANMI FPRTHTNQFD
EGGAGGDRGR RLPSDALAMM QDSAPGSSDN IGRHSSSRGS SSRSGLSHRS NNTKRGHAKT
LTKHQHVEDQ LQMKGLHDHH KLSMQSEYTE VANGERGKET GSAQSNEPME EEMEDLQEDV
VDKVGSDKDE DYVPEDEAED S
//
