ID A0A0D9QWF1_CHLSB Unreviewed; 657 AA.
AC A0A0D9QWF1;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Rho GTPase activating protein 24 {ECO:0000313|Ensembl:ENSCSAP00000000690.1};
GN Name=ARHGAP24 {ECO:0000313|Ensembl:ENSCSAP00000000690.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000000690.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000000690.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000000690.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AQIB01016609; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007997326.1; XM_007999135.1.
DR AlphaFoldDB; A0A0D9QWF1; -.
DR STRING; 60711.ENSCSAP00000000690; -.
DR Ensembl; ENSCSAT00000002375.1; ENSCSAP00000000690.1; ENSCSAG00000004344.1.
DR GeneID; 103235914; -.
DR CTD; 83478; -.
DR eggNOG; KOG4270; Eukaryota.
DR GeneTree; ENSGT00950000183015; -.
DR OMA; ELLYYYK; -.
DR OrthoDB; 48967at2759; -.
DR BioGRID-ORCS; 103235914; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 7.
DR Bgee; ENSCSAG00000004344; Expressed in fibroblast and 5 other cell types or tissues.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR CDD; cd04390; RhoGAP_ARHGAP22_24_25; 1.
DR Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR InterPro; IPR000198; RhoGAP_dom.
DR PANTHER; PTHR15228:SF19; RHO GTPASE-ACTIVATING PROTEIN 24; 1.
DR PANTHER; PTHR15228; SPERMATHECAL PHYSIOLOGY VARIANT; 1.
DR Pfam; PF00620; RhoGAP; 1.
DR SMART; SM00324; RhoGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR PROSITE; PS50238; RHOGAP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965}.
FT DOMAIN 43..237
FT /note="Rho-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50238"
FT REGION 262..385
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 491..550
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 561..637
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 262..318
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 337..385
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..550
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 657 AA; 73617 MW; ACAD8763090234FD CRC64;
MMPEDRNSGG RPAGALASTP FIPKTTYRRI KRCFSFRKGI FGQKLEDTVR YEKRYGNRLA
PMLVEQCVDF IRQRGLKEEG LFRLPGQANL VKELQDAFDC GEKPSFDSNT DVHTVASLLK
LYLRELPEPV IPYAKYEDFL SCAKLLSKEE EAGVKELAKQ VKSLPVVNYN LLKYICRFLD
EVQSYSGVNK MSVQNLATVF GPNILRPKVE DPLTIMEGTV VVQQLMSMMI SKHDSLFPKD
AELQSKPQDG VSNNNNEIQK KATTGQLQNK ENNNTKNSPG RQCSWDKSES PQRSSMDNGS
PIALSGSKTN SPRNSVHKLD VSRSPPLMVK KNPAFNKGSG IVTNGSFSSS NAEGLEKAQT
TPNGSLQSRR TSSLKGSGTK MGTHSVQNGT VRMGILNSDT HGNPANGRNM SWLPNGYVTL
RDNKQKEQAG ESGQHNRLST YDNVHQQFSM MNLDDKQSID SATWSTSSCE ISLPENSNSC
RSSTTTCPEQ DFYGGNFEDP VLDGPPQEDL SHPRDYESKS DHRSVGGRSS RATSSSDNSE
TFVGNSSSNH SALHSLVSSL KQEMTKQKIE YESRIKSLEQ RNLTLETEMM SLHDELDQER
KKFTMIEIKM RNAERAKEDA EKRNDMLQKE MEQFFSTFGE LTVEPRRTER GNTIWIQ
//
