ID A0A0D9QZ43_CHLSB Unreviewed; 1321 AA.
AC A0A0D9QZ43;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE SubName: Full=Spalt like transcription factor 1 {ECO:0000313|Ensembl:ENSCSAP00000001632.1};
GN Name=SALL1 {ECO:0000313|Ensembl:ENSCSAP00000001632.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000001632.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000001632.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000001632.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the sal C2H2-type zinc-finger protein family.
CC {ECO:0000256|ARBA:ARBA00038474}.
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DR EMBL; AQIB01142978; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007991206.1; XM_007993015.1.
DR RefSeq; XP_007991215.1; XM_007993024.1.
DR STRING; 60711.ENSCSAP00000001632; -.
DR Ensembl; ENSCSAT00000003350.1; ENSCSAP00000001632.1; ENSCSAG00000005319.1.
DR GeneID; 103232763; -.
DR KEGG; csab:103232763; -.
DR CTD; 6299; -.
DR eggNOG; KOG1074; Eukaryota.
DR GeneTree; ENSGT00940000155938; -.
DR OMA; QELHKSP; -.
DR OrthoDB; 2880677at2759; -.
DR BioGRID-ORCS; 103232763; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 5.
DR Bgee; ENSCSAG00000005319; Expressed in liver and 4 other cell types or tissues.
DR GO; GO:0010369; C:chromocenter; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0000792; C:heterochromatin; IEA:Ensembl.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008013; F:beta-catenin binding; IEA:Ensembl.
DR GO; GO:0001227; F:DNA-binding transcription repressor activity, RNA polymerase II-specific; IEA:Ensembl.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:Ensembl.
DR GO; GO:0030325; P:adrenal gland development; IEA:Ensembl.
DR GO; GO:0048566; P:embryonic digestive tract development; IEA:Ensembl.
DR GO; GO:0042733; P:embryonic digit morphogenesis; IEA:Ensembl.
DR GO; GO:0008406; P:gonad development; IEA:Ensembl.
DR GO; GO:0007507; P:heart development; IEA:Ensembl.
DR GO; GO:0003337; P:mesenchymal to epithelial transition involved in metanephros morphogenesis; IEA:Ensembl.
DR GO; GO:0061034; P:olfactory bulb mitral cell layer development; IEA:Ensembl.
DR GO; GO:0021983; P:pituitary gland development; IEA:Ensembl.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0030177; P:positive regulation of Wnt signaling pathway; IEA:Ensembl.
DR CDD; cd20908; SUF4-like; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 8.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23233; SAL-LIKE PROTEIN; 1.
DR PANTHER; PTHR23233:SF51; SAL-LIKE PROTEIN 1; 1.
DR Pfam; PF00096; zf-C2H2; 6.
DR Pfam; PF13912; zf-C2H2_6; 1.
DR Pfam; PF12874; zf-met; 1.
DR SMART; SM00355; ZnF_C2H2; 9.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 5.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 9.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 9.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 446..473
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 474..501
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 703..730
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 731..758
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 763..790
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 998..1025
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1026..1053
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1131..1158
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1159..1186
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 1..43
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 77..167
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 314..333
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 576..643
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 787..853
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 889..966
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1092..1117
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 18..43
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 109..128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..167
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 617..642
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..820
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 838..853
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 889..936
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1321 AA; 140010 MW; 778DE02A9E5ADCCC CRC64;
MSRRKQAKPQ HFQSDPEVAS LPRRDGDTEK GQPSRPTKSK DAHVCGRCCA EFFELSDLLL
HKKNCTKNQL VLIVNENPAS PPETFSPSPP PDNPDEQMSD TVNKTDQADC SDLSEHNGLD
REESMEVEAP VANKSGSGPS SGSHSSTAPS SSSSSSSSSS GSSTGTSAIT TSLPQLGDLT
TLGNFSVINS NVIIENLQST KVAVAQFSQE ARCGGASGGK LAVPALMEQL LALQQQQIHQ
LQLIEQIRHQ ILLLASQNAD LPTSSSPSQG TLRTSANPLS TLSSHLSQQL AAAAGLAQSL
ASQSASISGV KQLPPIQLPQ SSSGNTIIPS NSGSSPSMNI LAAAVTTPSS EKVASSAGAS
HVSNPAVSSS SSPAFAISSL LSPASNPLLH QLVPANSVFP SPLPDIGTTA EDLDSLSALA
QQRKSKPPNV TAFEAKSTSD EAFFKHKCRF CAKVFGSGSV LQIHLRSHTG ERPFKCNICG
NGFSTKGNLK VHFQRHKEKY PHIQMNPYPV PEHLDNIPTS TGIPYGMSIP PEKPVTSQLD
TKAVLATLTT SVGLPLPPTL PSLILFIKTE EPAPIPISHS ATSPPGSVKS DSGGPEPATR
NLGGLPEEAE GSTLPPSGGK SEESGMVTNS VPTASSSALS SPAADCGPVG SATTFTNPLL
PLMSEQFKAR FPFGGLLDSA QASETSKLQQ LVENIDKKAT DPNECIICHR VLSCQSALKM
HYRTHTGERP FKCKICGRAF TTKGNLKTHY SVHRAMPPLR VQHSCPICQK KFTNAVVLQQ
HIRMHMGGQI PNTPVPDSYP ESMESDTGSF DEKNFDDLDN FSDDNMEDCP EGSIPDTPKS
ADASQDSLSS SPLPLEMSSI AALENQMKMI NAGLAEQLQA SLKSVENGSV EGDVLTNDSS
SVGGDMESQS AGSPAISEST SSMQALSPSN STQEFHKSPS VEEKPQRGVP SEFANGLSPT
PVNGGALDLT SSHAEKIIKE DSLGILFPFR DRGKFKNTAC DICGKTFACQ SALDIHYRSH
TKERPFICTV CNRGFSTKGN LKQHMLTHQM RDLPSQLFEP SSNLGPNQNS AVIPANSLSS
LIKTEVNGFV HISPQDSKDT PTSHVPSGPL SSSATSPVLL PALPRRTPKQ HYCNTCGKTF
SSSSALQIHE RTHTGEKPFA CTICGRAFTT KGNLKVHMGT HMWNSTPARR GRRLSVDGPM
TFLGGNPVKF PEMFQKDLAA RSGSGDPSSF WNQYAAALSN GLAMKANEIS VIQNGGIPPI
PGSLGSGNSS PISGLTGNLE RLQNSEPNAP LAGLEKMASS ENGTNFRFTR FVEDSKEIVT
S
//
