ID A0A0D9QZ69_CHLSB Unreviewed; 1871 AA.
AC A0A0D9QZ69;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=Programmed cell death 11 {ECO:0000313|Ensembl:ENSCSAP00000001658.1};
GN Name=PDCD11 {ECO:0000313|Ensembl:ENSCSAP00000001658.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000001658.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000001658.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000001658.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AQIB01042521; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01042522; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_007962203.1; XM_007964012.1.
DR STRING; 60711.ENSCSAP00000001658; -.
DR Ensembl; ENSCSAT00000003378.1; ENSCSAP00000001658.1; ENSCSAG00000005346.1.
DR GeneID; 103216456; -.
DR CTD; 22984; -.
DR eggNOG; KOG1070; Eukaryota.
DR GeneTree; ENSGT00390000012228; -.
DR OMA; GQYLRAY; -.
DR OrthoDB; 167902at2759; -.
DR BioGRID-ORCS; 103216456; 0 hits in 9 CRISPR screens.
DR Proteomes; UP000029965; Chromosome 9.
DR Bgee; ENSCSAG00000005346; Expressed in fibroblast and 7 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0051059; F:NF-kappaB binding; IEA:Ensembl.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
DR CDD; cd05701; S1_Rrp5_repeat_hs10; 1.
DR CDD; cd05702; S1_Rrp5_repeat_hs11_sc8; 1.
DR CDD; cd05703; S1_Rrp5_repeat_hs12_sc9; 1.
DR CDD; cd05704; S1_Rrp5_repeat_hs13; 1.
DR CDD; cd05705; S1_Rrp5_repeat_hs14; 1.
DR CDD; cd05693; S1_Rrp5_repeat_hs1_sc1; 1.
DR CDD; cd05694; S1_Rrp5_repeat_hs2_sc2; 1.
DR CDD; cd05695; S1_Rrp5_repeat_hs3; 1.
DR CDD; cd05696; S1_Rrp5_repeat_hs4; 1.
DR CDD; cd05697; S1_Rrp5_repeat_hs5; 1.
DR CDD; cd05698; S1_Rrp5_repeat_hs6_sc5; 1.
DR CDD; cd05699; S1_Rrp5_repeat_hs7; 1.
DR CDD; cd04461; S1_Rrp5_repeat_hs8_sc7; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 8.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR003107; HAT.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR045209; Rrp5.
DR InterPro; IPR048058; Rrp5_S1_rpt_hs11_sc8.
DR InterPro; IPR048059; Rrp5_S1_rpt_hs1_sc1.
DR InterPro; IPR003029; S1_domain.
DR InterPro; IPR008847; Suf.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR PANTHER; PTHR23270; PROGRAMMED CELL DEATH PROTEIN 11 PRE-RRNA PROCESSING PROTEIN RRP5; 1.
DR PANTHER; PTHR23270:SF10; PROTEIN RRP5 HOMOLOG; 1.
DR Pfam; PF00575; S1; 4.
DR Pfam; PF05843; Suf; 1.
DR SMART; SM00386; HAT; 7.
DR SMART; SM00316; S1; 12.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 12.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50126; S1; 12.
PE 4: Predicted;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW rRNA processing {ECO:0000256|ARBA:ARBA00022552}.
FT DOMAIN 83..171
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 187..258
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 281..346
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 365..436
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 453..522
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 542..611
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 636..707
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 729..798
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1036..1109
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1149..1222
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1230..1298
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT DOMAIN 1324..1396
FT /note="S1 motif"
FT /evidence="ECO:0000259|PROSITE:PS50126"
FT REGION 1..62
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1394..1530
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1549..1586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 10..24
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1414..1456
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1466..1526
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1557..1586
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1871 AA; 208752 MW; 2936982395BC866C CRC64;
MAALEESFPR GGTRKIHKPE KAFQQSVEQD NLFDISTEEG STKRKKSQKG PANTKKLKIE
KRESSKSARE KFEILSVESL CEGMRILGCV KEVNELELVI SLPNGLQGFV QVTEICDAYT
KKLNEQVTQE QPLKDLLHLP ELFSPGMLVR CVVSSLGITD RGKKSVKLSL NPKNVNRVLS
AEALKPGMLL TGTVSSLEDH GYLVDIGVDG TRAFLPLLKA QEYIRQKNKG AKLKVGQYLN
CIVEKVKGNG GVVSLSVGHS EVSTAIATEE QSWTLNNLLP GLVVKAQVQK VTPFGLTLNF
LTFFTGVVDF MHLDPKKAGT YFSNQAVRAC ILCVHPRTRV VRLSLRPIFL QPGRPLTRLS
CQNLGAVLDD VPVQGFFKKA GATFRLKDGV LAYARLSHLS DSKNVFNPET FKPGNTHKCR
IIDYSQMDEL ALLSLRTSII EAQYLRYHDI EPGAVVKGVV LTIKSYGMLV KVGEQMRGLV
PPMHLADILM KNPEKKYHIG DEVKCRVLLC DPEAKKLMMT LKKTLVESKL PVITCYADAK
PGLQTHGFII RVKDYGCIVK FYNNVQGLVP KHELSTEYIP DPERVFYTGQ VVKVAVLNCE
PSKERMLLSF KLSSDPEPKK EPAGHNQKKG KAINIGQLVD VKVLEKTKDG LEVAVLPHNI
RAFLPTSHLS DHVANGPLLH HWLQAGDILH RVLCLSQSEG HVLLCRKPAL VSTVEGGQDP
KNFSEIHPGM LLIGFVKSIK DYGVFIQFPS GLSGLAPKAI MSDKFVTSTS DHFVEGQTVA
AKVTNVDEEK QRMLLSLRLS DCALGDLATT SLLLLSQCLE ELQGVRSLMS NRDSVLIQTL
AEMTPGMFLD LVVQEVLEDG SVVFSGGPVP DLVLRASRYH RAGQEVESGQ KKKVVILNVD
LLKLEVHVSL HQDLVNRKAK KLRKGSEHQA IVQHLEKSFA IASLVETGHL AAFSLTSHLN
DTFRFDSEKL QVGQGVSLTL KTTEPGVTGL LLAVEGPAAK RTMRPTRKDS ETIDEDEEVD
PALTVGTIKK HTLSIGDMVT GTVKSIKPTH VVVTLEDGII GCIHASHILD DVPEGISPTT
KLKVGKTVTA RVIGGRDMKT FKFLPISHPR FVRTIPELSV RPSELEDGHT ALNTHSVSPV
EKIKQYQAGQ TVTCFLKKYN VVKKWLEVEI APDIRGRIPL LLTSLSFKVL KHPDKKFRVG
QALRATVVGP DSSKAFLCLS LIGPHKLEEG EVAMGRVVKV TPNEGLTVSF PFGKIGTVSI
FHVSDSYSEM PLEDFVPQKV VRCYILSTAD SVLTLSLRSS RTNPETKSKV EDPEINSIQD
IKEGQLLRGY VGSIQPHGVF FRLGPSVVGL ARYSHVSQHS LSKKALYNKH LPEGKLLTAR
VLRLNHQKNL VELSFLPGDT GKPDLLSASL EGPLPKQEER KTEAEERYQK GEKKNQKRNE
KKNQKGQEEV ELPSKEKQQP QKPQAQKRGG RERRESGSEQ ERVSKKPKKA GPSEEDDSLM
DVYYREGKEE AEETNVLPKE KQTKPAEVPR LQLSSGFAWN VGLDSLTPAL PPLAESSDSE
EDEKPHQTTK KKSKKERELE KQKAEKELSR IEEALMDPGR QPESADDFDR LVLSSPNSSI
LWLQYMAFHL QATEIEKARA VAERALKTIS FREEQEKLNV WVALLNLENM YGSQESLTKV
FERAVQYNEP LKVFLHLADI YAKSEKFQEA GELYNRMLKR FRQEKAVWIK YGAFLLRRSQ
AGASHRVLQR ALECLPSKEH VDVIAKFAQL EFQLGDAERA KAIFENMLST YPKRTDVWSV
YIDMTIKHGS QKAVRDIFER VIHLSLAPKR MKFFFKRYLD YEKQHGTEKD VQAVKAKALE
YVEAKSSVLE D
//
