ID A0A0D9QZQ3_CHLSB Unreviewed; 440 AA.
AC A0A0D9QZQ3;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE SubName: Full=Target of myb1 like 1 membrane trafficking protein {ECO:0000313|Ensembl:ENSCSAP00000001842.1};
GN Name=TOM1L1 {ECO:0000313|Ensembl:ENSCSAP00000001842.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000001842.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000001842.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000001842.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TOM1 family. {ECO:0000256|ARBA:ARBA00007708,
CC ECO:0000256|PIRNR:PIRNR036948}.
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DR EMBL; AQIB01117374; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01117375; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9QZQ3; -.
DR STRING; 60711.ENSCSAP00000001842; -.
DR Ensembl; ENSCSAT00000003561.1; ENSCSAP00000001842.1; ENSCSAG00000005531.1.
DR eggNOG; KOG1087; Eukaryota.
DR GeneTree; ENSGT00940000160240; -.
DR OMA; HHHKGAQ; -.
DR Proteomes; UP000029965; Chromosome 16.
DR Bgee; ENSCSAG00000005531; Expressed in liver and 6 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005768; C:endosome; IEA:Ensembl.
DR GO; GO:0030276; F:clathrin binding; IEA:Ensembl.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0030295; F:protein kinase activator activity; IEA:Ensembl.
DR GO; GO:0019901; F:protein kinase binding; IEA:Ensembl.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0045839; P:negative regulation of mitotic nuclear division; IEA:Ensembl.
DR GO; GO:0031954; P:positive regulation of protein autophosphorylation; IEA:Ensembl.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0007165; P:signal transduction; IEA:Ensembl.
DR CDD; cd14237; GAT_TM1L1; 1.
DR CDD; cd16997; VHS_Tom1L1; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR014645; TOM1.
DR InterPro; IPR027428; TOM1L1_GAT_dom.
DR InterPro; IPR047013; TOM1L1_VHS_dom.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR13856:SF28; TOM1-LIKE PROTEIN 1; 1.
DR PANTHER; PTHR13856; VHS DOMAIN CONTAINING PROTEIN FAMILY; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR PIRSF; PIRSF036948; TOM1; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927,
KW ECO:0000256|PIRNR:PIRNR036948};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|PIRNR:PIRNR036948}.
FT DOMAIN 22..154
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 200..288
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 155..179
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 297..330
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 412..440
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 162..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..317
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 440 AA; 49096 MW; 55A8FDFFBDDC0A54 CRC64;
MAFGKSHRDP YATSVGHLIE KATFAAVQTE DWGQFMHICD IINTTQDGPK DAVKALKKRI
SKNYNHKEIQ LTLSLIDMCV QNCGPSFQSL IVKKEFVKEN LVKLLNPRYN LPLDIQNRIL
NFIKAWSQGF PGGVDVSEVK EVYLDLLKKG VQFPPSEAEA ETARQETAQI SSNPPTSVPT
APALSSVIAP KNSTITLVPE QIGKLHSELD MVKMNVRVMS AILMENTPGS ENQEDIELLQ
KLYKTGREMQ ERIMDLLVVV ENEDVTVELI QVNEDLNNAI LGYERFTRNQ QRILEQNNQK
EATSTTSEPS APSQDLLDLS PSPRMPRDTL GELKTMNNQL SDLNFSSPSS DVTNNLKPSL
HPQMDLLALE NTEIPLFSQR ISQNLTSSHA YDNFLEHSHS VFLQPVSLQT TAAAPSNQSL
PPLPSNHPAM TKSDLQPPNY
//
