ID A0A0D9R0D1_CHLSB Unreviewed; 400 AA.
AC A0A0D9R0D1;
DT 27-MAY-2015, integrated into UniProtKB/TrEMBL.
DT 27-MAY-2015, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Zinc transporter ZIP13 {ECO:0000256|ARBA:ARBA00040592};
DE AltName: Full=Solute carrier family 39 member 13 {ECO:0000256|ARBA:ARBA00042542};
DE AltName: Full=Zrt- and Irt-like protein 13 {ECO:0000256|ARBA:ARBA00042972};
GN Name=SLC39A13 {ECO:0000313|Ensembl:ENSCSAP00000002070.1};
OS Chlorocebus sabaeus (Green monkey) (Cercopithecus sabaeus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Chlorocebus.
OX NCBI_TaxID=60711 {ECO:0000313|Ensembl:ENSCSAP00000002070.1, ECO:0000313|Proteomes:UP000029965};
RN [1] {ECO:0000313|Ensembl:ENSCSAP00000002070.1, ECO:0000313|Proteomes:UP000029965}
RP NUCLEOTIDE SEQUENCE.
RA Warren W., Wilson R.K.;
RL Submitted (MAR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSCSAP00000002070.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Zn(2+)(in) = Zn(2+)(out); Xref=Rhea:RHEA:29351,
CC ChEBI:CHEBI:29105; Evidence={ECO:0000256|ARBA:ARBA00034634};
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004156}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ZIP transporter (TC 2.A.5) family.
CC {ECO:0000256|ARBA:ARBA00006939}.
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DR EMBL; AQIB01081052; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AQIB01081053; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A0D9R0D1; -.
DR STRING; 60711.ENSCSAP00000002070; -.
DR Ensembl; ENSCSAT00000003794.1; ENSCSAP00000002070.1; ENSCSAG00000005760.1.
DR eggNOG; KOG2694; Eukaryota.
DR GeneTree; ENSGT00940000157349; -.
DR OMA; TGDSVHC; -.
DR Proteomes; UP000029965; Chromosome 1.
DR Bgee; ENSCSAG00000005760; Expressed in fibroblast and 7 other cell types or tissues.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:Ensembl.
DR GO; GO:0000139; C:Golgi membrane; IEA:Ensembl.
DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:Ensembl.
DR GO; GO:0042803; F:protein homodimerization activity; IEA:Ensembl.
DR GO; GO:0005385; F:zinc ion transmembrane transporter activity; IEA:Ensembl.
DR GO; GO:0050873; P:brown fat cell differentiation; IEA:Ensembl.
DR GO; GO:0061448; P:connective tissue development; IEA:Ensembl.
DR GO; GO:0006882; P:intracellular zinc ion homeostasis; IEA:Ensembl.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR16950; ZINC TRANSPORTER SLC39A7 HISTIDINE-RICH MEMBRANE PROTEIN KE4; 1.
DR PANTHER; PTHR16950:SF16; ZINC TRANSPORTER ZIP13; 1.
DR Pfam; PF02535; Zip; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000029965};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 101..124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..167
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 187..206
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 346..370
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 400 AA; 42089 MW; FF702844141B891D CRC64;
MPGSLGGRRE APRFLSRCAA KAGSSCRWPS CFSVRGMPGC PCPGCGMAGP RLLFLTALAL
ELLGRAGGSQ PALRSRGTAT ACRLDNKESE SWGALLSGER LDTWICSLLG SLMVGLSGVF
PLLVIPLEMG TMLRSEAGAW RLKQLLSFAL GGLLGNVFLH LLPEAWAYTC SAGPGGEGQS
LQQQQQLGLW VIAGILTFLA LEKMFLDSKA EGTSQAPNKD PTAAAAALNG GHCLAQPAAE
PGLGAVVRSI KVSGYLNLLA NTIDNFTHGL AVAASFLVSK KIGLLTTMAI LLHEIPHEVG
DFAILLRAGF DRWSAAKLQL STALGGLLGA GFAICTQSPK GVEETAAWVL PFTSGGFLYI
ALVNVLPDLL EEEDPWRSLQ QLLLLCAGIV VMVLFSIFVD
//
